Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              20     390
XP_005269721                                                           20     390
NP_060009                                                              18    1935
XP_006721125                                                           18    1935
NP_008952                                                              17    3301
NP_001269645                                                           16    5631
NP_036579                                                              16    5631
NP_001269646                                                           16    5631
NP_001269647                                                           16    5631
NP_001034463                                                           16    5631
NP_001274268                                                           16    5631
NP_001073138                                                           16    5631
NP_112187                                                              16    5631
NP_001274266                                                           16    5631
NP_001274267                                                           16    5631
NP_443198                                                              16    5631
XP_005250173                                                           16    5631
NP_001275668                                                           16    7355
NP_004399                                                              16    7355
NP_001275667                                                           16    7355
NP_001005336                                                           16    7355
NP_001275666                                                           16    7355
NP_001275938                                                           16    7355
NP_001275990                                                           16    7355
NP_001275987                                                           16    7355
NP_203754                                                              16    7355
NP_112168                                                              16    7355
NP_060512                                                              16    7355
XP_006722030                                                           16    7355
XP_005258052                                                           16    7355
XP_006718789                                                           16    7355
XP_006718788                                                           16    7355
XP_005274419                                                           16    7355
XP_006718343                                                           16    7355
XP_006718342                                                           16    7355
XP_006718341                                                           16    7355
XP_006717057                                                           16    7355
XP_006717056                                                           16    7355
XP_005251826                                                           16    7355
XP_005251825                                                           16    7355
XP_005251821                                                           16    7355
XP_005251820                                                           16    7355
XP_006717055                                                           16    7355
XP_006713324                                                           16    7355
NP_733793                                                              15    9605
NP_004832                                                              15    9605
NP_005610                                                              15    9605
NP_001273424                                                           15    9605
NP_006181                                                              15    9605
NP_062546                                                              15    9605
NP_996783                                                              15    9605
NP_919269                                                              15    9605
NP_659206                                                              15    9605
NP_001182719                                                           15    9605
NP_659205                                                              15    9605
NP_001257381                                                           15    9605
NP_006790                                                              15    9605
XP_006726617                                                           15    9605
XP_005255108                                                           15    9605
XP_006720675                                                           15    9605
XP_006720674                                                           15    9605
XP_006720673                                                           15    9605
XP_006720672                                                           15    9605
XP_005254605                                                           15    9605
XP_005254604                                                           15    9605
XP_006720409                                                           15    9605
XP_005264966                                                           15    9605
XP_006712618                                                           15    9605
XP_005245679                                                           15    9605
XP_005245678                                                           15    9605
XP_005245677                                                           15    9605
XP_006711697                                                           15    9605
XP_006710039                                                           15    9605
NP_001265438                                                           15    9605
NP_001265437                                                           15    9605
NP_037388                                                              15    9605
NP_001275688                                                           15    9605
>NP_036462
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GKRDITSRF 9
           GKRDI SRF
Sbjct: 589 GKRDIRSRF 597
>XP_005269721
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GKRDITSRF 9
           GKRDI SRF
Sbjct: 589 GKRDIRSRF 597
>NP_060009
          Length = 4116

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GKRDITSRF 9
            G+ DIT RF
Sbjct: 2195 GRNDITGRF 2203
>XP_006721125
          Length = 4070

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GKRDITSRF 9
            G+ DIT RF
Sbjct: 2149 GRNDITGRF 2157
>NP_008952
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  RDITSRF 9
          RDIT+RF
Sbjct: 83 RDITARF 89
>NP_001269645
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           G RD+T+R
Sbjct: 372 GNRDLTTR 379
>NP_036579
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           G RD+T+R
Sbjct: 372 GNRDLTTR 379
>NP_001269646
          Length = 1226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           G RD+T+R
Sbjct: 372 GNRDLTTR 379
>NP_001269647
          Length = 1167

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           G RD+T+R
Sbjct: 314 GNRDLTTR 321
>NP_001034463
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           DITSRF
Sbjct: 317 DITSRF 322
>NP_001274268
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKRDITSRF 9
           GK+D+T  F
Sbjct: 93  GKKDVTQIF 101
>NP_001073138
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKRDITSRF 9
           GK+D+T  F
Sbjct: 93  GKKDVTQIF 101
>NP_112187
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKRDITSRF 9
           GK+D+T  F
Sbjct: 93  GKKDVTQIF 101
>NP_001274266
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKRDITSRF 9
           GK+D+T  F
Sbjct: 93  GKKDVTQIF 101
>NP_001274267
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKRDITSRF 9
           GK+D+T  F
Sbjct: 93  GKKDVTQIF 101
>NP_443198
          Length = 928

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KRDITSRF 9
          +RD+TS+F
Sbjct: 51 QRDLTSQF 58
>XP_005250173
          Length = 1222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           G RD+T+R
Sbjct: 372 GNRDLTTR 379
>NP_001275668
          Length = 864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>NP_004399
          Length = 864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>NP_001275667
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>NP_001005336
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>NP_001275666
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>NP_001275938
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KRDITS 7
           KRDITS
Sbjct: 128 KRDITS 133
>NP_001275990
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RDITSR 8
          RDITSR
Sbjct: 67 RDITSR 72
>NP_001275987
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RDITSR 8
          RDITSR
Sbjct: 26 RDITSR 31
>NP_203754
          Length = 1729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GKRDITSRF 9
           G+RD TS++
Sbjct: 770 GERDWTSKY 778
>NP_112168
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RDITSR 8
          RDITSR
Sbjct: 67 RDITSR 72
>NP_060512
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KRDITS 7
           KRDITS
Sbjct: 128 KRDITS 133
>XP_006722030
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KRDITS 7
           KRDITS
Sbjct: 128 KRDITS 133
>XP_005258052
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KRDITS 7
           KRDITS
Sbjct: 128 KRDITS 133
>XP_006718789
          Length = 1053

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GKRDITSRF 9
           G+RD TS++
Sbjct: 94  GERDWTSKY 102
>XP_006718788
          Length = 1729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GKRDITSRF 9
           G+RD TS++
Sbjct: 770 GERDWTSKY 778
>XP_005274419
          Length = 1808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GKRDITSRF 9
           G+RD TS++
Sbjct: 849 GERDWTSKY 857
>XP_006718343
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RDITSR 8
          RDITSR
Sbjct: 26 RDITSR 31
>XP_006718342
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RDITSR 8
          RDITSR
Sbjct: 67 RDITSR 72
>XP_006718341
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RDITSR 8
          RDITSR
Sbjct: 26 RDITSR 31
>XP_006717057
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>XP_006717056
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>XP_005251826
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>XP_005251825
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>XP_005251821
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>XP_005251820
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>XP_006717055
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GKRDITS 7
           GK+DIT+
Sbjct: 244 GKKDITA 250
>XP_006713324
          Length = 1285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    KRDITSRF 9
            KRD+  RF
Sbjct: 1257 KRDVKKRF 1264
>NP_733793
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+DI+ R
Sbjct: 612 GKQDISER 619
>NP_004832
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+DI+ R
Sbjct: 464 GKQDISER 471
>NP_005610
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          G+RD T+R
Sbjct: 77 GRRDSTAR 84
>NP_001273424
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 630 DLTSRF 635
>NP_006181
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KRDITSRF 9
           KRD+  RF
Sbjct: 319 KRDLLERF 326
>NP_062546
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 623 DLTSRF 628
>NP_996783
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          G+RD T+R
Sbjct: 77 GRRDSTAR 84
>NP_919269
          Length = 1843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    GKRDIT 6
            GK+DIT
Sbjct: 1720 GKKDIT 1725
>NP_659206
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          G+R ITSR
Sbjct: 34 GRRVITSR 41
>NP_001182719
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KRDITS 7
           KRD+TS
Sbjct: 146 KRDVTS 151
>NP_659205
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          G+R ITSR
Sbjct: 34 GRRVITSR 41
>NP_001257381
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          G+R ITSR
Sbjct: 34 GRRVITSR 41
>NP_006790
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          G+R ITSR
Sbjct: 34 GRRVITSR 41
>XP_006726617
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GKRDIT 6
           GK+DIT
Sbjct: 799 GKKDIT 804
>XP_005255108
          Length = 227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          G+R ITSR
Sbjct: 34 GRRVITSR 41
>XP_006720675
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 535 DLTSRF 540
>XP_006720674
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 535 DLTSRF 540
>XP_006720673
          Length = 1013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 623 DLTSRF 628
>XP_006720672
          Length = 1053

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 623 DLTSRF 628
>XP_005254605
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 623 DLTSRF 628
>XP_005254604
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DITSRF 9
           D+TSRF
Sbjct: 623 DLTSRF 628
>XP_006720409
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GKRDIT 6
           GK+DIT
Sbjct: 799 GKKDIT 804
>XP_005264966
          Length = 1843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    GKRDIT 6
            GK+DIT
Sbjct: 1720 GKKDIT 1725
>XP_006712618
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KRDITSRF 9
           KRD+  RF
Sbjct: 319 KRDLLERF 326
>XP_005245679
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+DI+ R
Sbjct: 464 GKQDISER 471
>XP_005245678
          Length = 1145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+DI+ R
Sbjct: 467 GKQDISER 474
>XP_005245677
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+DI+ R
Sbjct: 495 GKQDISER 502
>XP_006711697
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+DI+ R
Sbjct: 504 GKQDISER 511
>XP_006710039
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GKRDIT 6
           GK+DIT
Sbjct: 695 GKKDIT 700
>NP_001265438
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GKRDITSR 8
          GK+D TS+
Sbjct: 91 GKKDSTSK 98
>NP_001265437
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+D TS+
Sbjct: 93  GKKDSTSK 100
>NP_037388
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+D TS+
Sbjct: 118 GKKDSTSK 125
>NP_001275688
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GKRDITSR 8
           GK+D TS+
Sbjct: 117 GKKDSTSK 124
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.143    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 460,955
Number of extensions: 988
Number of successful extensions: 77
Number of sequences better than 10000.0: 77
Number of HSP's gapped: 77
Number of HSP's successfully gapped: 77
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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