Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
XP_006718908                                                           19     869
XP_005271621                                                           19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
NP_149100                                                              18    1935
XP_005264686                                                           18    1935
NP_073754                                                              17    3301
NP_001264994                                                           16    7355
NP_001264995                                                           16    7355
NP_001264996                                                           16    7355
NP_001264993                                                           16    7355
NP_055144                                                              16    7355
XP_006715531                                                           16    7355
XP_006715530                                                           16    7355
NP_056529                                                              15    9605
NP_002705                                                              15    9605
XP_006726166                                                           15    9605
XP_006726165                                                           15    9605
XP_006726164                                                           15    9605
XP_006726163                                                           15    9605
XP_006726071                                                           15    9605
XP_006726070                                                           15    9605
XP_006726069                                                           15    9605
XP_006726068                                                           15    9605
XP_006725978                                                           15    9605
XP_006725977                                                           15    9605
XP_006725976                                                           15    9605
XP_006725975                                                           15    9605
XP_006725886                                                           15    9605
XP_006725885                                                           15    9605
XP_006725884                                                           15    9605
XP_006725883                                                           15    9605
XP_006725769                                                           15    9605
XP_006725768                                                           15    9605
XP_006725767                                                           15    9605
XP_006725766                                                           15    9605
XP_006725555                                                           15    9605
XP_006725554                                                           15    9605
XP_006725553                                                           15    9605
XP_006725552                                                           15    9605
XP_006715196                                                           15    9605
XP_006715195                                                           15    9605
XP_006715194                                                           15    9605
XP_006715193                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIMVKLFVN 9
            GIMVKL VN
Sbjct: 1642 GIMVKLVVN 1650
>XP_006718908
          Length = 1708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GIMVKL VN
Sbjct: 294 GIMVKLVVN 302
>XP_005271621
          Length = 2708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIMVKLFVN 9
            GIMVKL VN
Sbjct: 1294 GIMVKLVVN 1302
>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIMVKLFVN 9
            GIMVKL VN
Sbjct: 1636 GIMVKLVVN 1644
>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIMVKLFVN 9
            GIMVKL VN
Sbjct: 1642 GIMVKLVVN 1650
>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIMVKLFVN 9
            GIMVKL VN
Sbjct: 1642 GIMVKLVVN 1650
>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIMVKLFVN 9
            GIMVKL VN
Sbjct: 1642 GIMVKLVVN 1650
>NP_149100
          Length = 783

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           G+MVKL+ N
Sbjct: 693 GVMVKLYPN 701
>XP_005264686
          Length = 703

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           G+MVKL+ N
Sbjct: 613 GVMVKLYPN 621
>NP_073754
          Length = 951

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IMVKLFVN 9
           +MV LFVN
Sbjct: 837 VMVNLFVN 844
>NP_001264994
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIMVKLFV 8
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_001264995
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIMVKLFV 8
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_001264996
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIMVKLFV 8
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_001264993
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIMVKLFV 8
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_055144
          Length = 1401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   GIMVKLF 7
           G+++KLF
Sbjct: 503 GVLIKLF 509
>XP_006715531
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIMVKLFV 8
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>XP_006715530
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIMVKLFV 8
           GI+V LFV
Sbjct: 603 GILVTLFV 610
>NP_056529
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GIMVKLFV 8
          G MVKL+V
Sbjct: 21 GKMVKLYV 28
>NP_002705
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726166
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726165
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726164
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726163
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726071
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726070
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726069
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006726068
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725978
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725977
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725976
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725975
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725886
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725885
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725884
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725883
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725769
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725768
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725767
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725766
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725555
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725554
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725553
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006725552
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006715196
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006715195
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006715194
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
>XP_006715193
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIMVKLFVN 9
           GI+ +LF+N
Sbjct: 492 GILQELFLN 500
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.156    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 294,027
Number of extensions: 424
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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