Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           20     390
NP_055903                                                              20     390
NP_060555                                                              17    3301
NP_001273188                                                           17    3301
NP_001035502                                                           17    3301
NP_001035501                                                           17    3301
NP_068746                                                              17    3301
NP_872309                                                              17    3301
NP_976044                                                              17    3301
NP_001274320                                                           17    3301
NP_001035500                                                           17    3301
XP_006711503                                                           17    3301
NP_060899                                                              17    4312
XP_006725524                                                           17    4312
XP_006725523                                                           17    4312
XP_005276828                                                           17    4312
XP_006726279                                                           17    4312
XP_006714722                                                           17    4312
XP_006714721                                                           17    4312
NP_001153682                                                           16    5631
NP_055066                                                              16    5631
NP_690597                                                              16    5631
NP_004897                                                              16    5631
NP_690596                                                              16    5631
NP_001257461                                                           16    5631
NP_001257460                                                           16    5631
NP_001257462                                                           16    5631
XP_006715896                                                           16    5631
XP_006715894                                                           16    5631
XP_006715893                                                           16    5631
NP_997465                                                              16    7355
NP_003622                                                              15    9605
NP_071899                                                              15    9605
NP_001177779                                                           15    9605
NP_001177776                                                           15    9605
NP_037448                                                              15    9605
NP_001008226                                                           15    9605
NP_001177778                                                           15    9605
NP_001177777                                                           15    9605
NP_036440                                                              15    9605
NP_001093639                                                           15    9605
NP_006830                                                              15    9605
NP_001093640                                                           15    9605
NP_001243334                                                           15    9605
NP_065880                                                              15    9605
NP_037375                                                              15    9605
NP_001129392                                                           15    9605
NP_001193486                                                           15    9605
XP_006718544                                                           15    9605
XP_006718543                                                           15    9605
XP_006718542                                                           15    9605
XP_005251580                                                           15    9605
XP_005264171                                                           15    9605
XP_005264170                                                           15    9605
XP_005264167                                                           15    9605
XP_005275822                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   EVDQTKNS 9
           EVDQTKNS
Sbjct: 752 EVDQTKNS 759
>NP_055903
          Length = 1723

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   EVDQTKNS 9
           EVDQTKNS
Sbjct: 752 EVDQTKNS 759
>NP_060555
          Length = 1041

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVDQTKNS 9
           E +QTKNS
Sbjct: 431 EAEQTKNS 438
>NP_001273188
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EVDQTKNS 9
          EV+QTKN+
Sbjct: 14 EVNQTKNA 21
>NP_001035502
          Length = 1031

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GEVDQTKNS 9
           G++ +TKNS
Sbjct: 541 GDIQKTKNS 549
>NP_001035501
          Length = 1006

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GEVDQTKNS 9
           G++ +TKNS
Sbjct: 516 GDIQKTKNS 524
>NP_068746
          Length = 669

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GEVDQTKNS 9
           G +D+TKN+
Sbjct: 93  GTIDKTKNN 101
>NP_872309
          Length = 191

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EVDQTKNS 9
          EV+QTKN+
Sbjct: 61 EVNQTKNA 68
>NP_976044
          Length = 1079

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GEVDQTKNS 9
           G++ +TKNS
Sbjct: 589 GDIQKTKNS 597
>NP_001274320
          Length = 1006

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GEVDQTKNS 9
           G++ +TKNS
Sbjct: 516 GDIQKTKNS 524
>NP_001035500
          Length = 1044

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GEVDQTKNS 9
           G++ +TKNS
Sbjct: 554 GDIQKTKNS 562
>XP_006711503
          Length = 860

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVDQTKNS 9
           E +QTKNS
Sbjct: 250 EAEQTKNS 257
>NP_060899
          Length = 2624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EVDQTKN 8
           E+DQT+N
Sbjct: 601 EIDQTEN 607
>XP_006725524
          Length = 2584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EVDQTKN 8
           E+DQT+N
Sbjct: 601 EIDQTEN 607
>XP_006725523
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EVDQTKN 8
           E+DQT+N
Sbjct: 601 EIDQTEN 607
>XP_005276828
          Length = 2584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EVDQTKN 8
           E+DQT+N
Sbjct: 601 EIDQTEN 607
>XP_006726279
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EVDQTKN 8
           E+DQT+N
Sbjct: 601 EIDQTEN 607
>XP_006714722
          Length = 2584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EVDQTKN 8
           E+DQT+N
Sbjct: 601 EIDQTEN 607
>XP_006714721
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EVDQTKN 8
           E+DQT+N
Sbjct: 601 EIDQTEN 607
>NP_001153682
          Length = 676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEVDQTKN 8
          G VDQTK+
Sbjct: 63 GVVDQTKD 70
>NP_055066
          Length = 675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEVDQTKN 8
          G VDQTK+
Sbjct: 63 GVVDQTKD 70
>NP_690597
          Length = 151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GEVDQTKN 8
           GE++QTK+
Sbjct: 126 GELEQTKD 133
>NP_004897
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GEVDQTKN 8
           GE++QTK+
Sbjct: 126 GELEQTKD 133
>NP_690596
          Length = 151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GEVDQTKN 8
           GE++QTK+
Sbjct: 126 GELEQTKD 133
>NP_001257461
          Length = 170

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GEVDQTKN 8
           GE++QTK+
Sbjct: 126 GELEQTKD 133
>NP_001257460
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GEVDQTKN 8
           GE++QTK+
Sbjct: 126 GELEQTKD 133
>NP_001257462
          Length = 170

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GEVDQTKN 8
           GE++QTK+
Sbjct: 126 GELEQTKD 133
>XP_006715896
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEVDQTKN 8
          G VDQTK+
Sbjct: 74 GVVDQTKD 81
>XP_006715894
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEVDQTKN 8
          G VDQTK+
Sbjct: 74 GVVDQTKD 81
>XP_006715893
          Length = 687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEVDQTKN 8
          G VDQTK+
Sbjct: 74 GVVDQTKD 81
>NP_997465
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VDQTKNS 9
           +DQT+NS
Sbjct: 230 LDQTRNS 236
>NP_003622
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVDQTKNS 9
           +VD +KNS
Sbjct: 305 DVDNSKNS 312
>NP_071899
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GEVDQTK 7
           GEVD+T+
Sbjct: 356 GEVDRTE 362
>NP_001177779
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           G VD+ KN
Sbjct: 257 GSVDKNKN 264
>NP_001177776
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           G VD+ KN
Sbjct: 257 GSVDKNKN 264
>NP_037448
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           G VD+ KN
Sbjct: 257 GSVDKNKN 264
>NP_001008226
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           G VD+ KN
Sbjct: 257 GSVDKNKN 264
>NP_001177778
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           G VD+ KN
Sbjct: 257 GSVDKNKN 264
>NP_001177777
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           G VD+ KN
Sbjct: 257 GSVDKNKN 264
>NP_036440
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GEVDQTKNS 9
           GEVDQ + +
Sbjct: 624 GEVDQNEET 632
>NP_001093639
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VDQTKNS 9
           +D+T+NS
Sbjct: 647 IDETRNS 653
>NP_006830
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VDQTKNS 9
           +D+T+NS
Sbjct: 648 IDETRNS 654
>NP_001093640
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VDQTKNS 9
           +D+T+NS
Sbjct: 637 IDETRNS 643
>NP_001243334
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GEVDQTKNS 9
           GEVDQ + +
Sbjct: 185 GEVDQNEET 193
>NP_065880
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           GE  QT+N
Sbjct: 435 GEASQTQN 442
>NP_037375
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EVDQTKN 8
           +VD TKN
Sbjct: 107 DVDSTKN 113
>NP_001129392
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           GE  QT+N
Sbjct: 435 GEASQTQN 442
>NP_001193486
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           GE  QT+N
Sbjct: 435 GEASQTQN 442
>XP_006718544
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GEVDQTKNS 9
           GEVDQ + +
Sbjct: 518 GEVDQNEET 526
>XP_006718543
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GEVDQTKNS 9
           GEVDQ + +
Sbjct: 529 GEVDQNEET 537
>XP_006718542
          Length = 1145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GEVDQTKNS 9
           GEVDQ + +
Sbjct: 607 GEVDQNEET 615
>XP_005251580
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GEVDQTKN 8
           GE  QT+N
Sbjct: 434 GEASQTQN 441
>XP_005264171
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VDQTKNS 9
           +D+T+NS
Sbjct: 605 IDETRNS 611
>XP_005264170
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VDQTKNS 9
           +D+T+NS
Sbjct: 616 IDETRNS 622
>XP_005264167
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VDQTKNS 9
           +D+T+NS
Sbjct: 636 IDETRNS 642
>XP_005275822
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  GEVDQT 6
          G+VDQT
Sbjct: 34 GDVDQT 39
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286    0.111    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 568,097
Number of extensions: 1434
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package