Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001274103                                                           16    5631
NP_000343                                                              16    5631
NP_689618                                                              16    5631
NP_036213                                                              16    5631
NP_150229                                                              16    5631
NP_005679                                                              16    5631
XP_006718349                                                           16    5631
XP_006714638                                                           16    5631
XP_006714637                                                           16    5631
XP_005248487                                                           16    5631
XP_005247116                                                           16    5631
XP_005247115                                                           16    5631
XP_005276063                                                           16    5631
NP_005912                                                              16    7355
NP_569079                                                              16    7355
NP_064520                                                              16    7355
NP_004906                                                              16    7355
NP_997511                                                              16    7355
NP_058198                                                              16    7355
NP_997512                                                              16    7355
NP_997510                                                              16    7355
NP_997057                                                              16    7355
NP_003777                                                              16    7355
NP_065166                                                              16    7355
XP_006723895                                                           16    7355
XP_005257820                                                           16    7355
XP_005249289                                                           16    7355
XP_005248577                                                           16    7355
XP_005248576                                                           16    7355
NP_001135977                                                           16    7355
NP_071452                                                              16    7355
NP_000855                                                              16    7355
NP_000483                                                              15    9605
NP_060720                                                              15    9605
NP_443148                                                              15    9605
NP_001166033                                                           15    9605
NP_001012661                                                           15    9605
XP_005258122                                                           15    9605
XP_006722225                                                           15    9605
XP_005258120                                                           15    9605
XP_005258121                                                           15    9605
XP_005258119                                                           15    9605
XP_006721725                                                           15    9605
XP_006721723                                                           15    9605
XP_006716420                                                           15    9605
XP_006716419                                                           15    9605
XP_006715905                                                           15    9605
NP_001138631                                                           15    9605
NP_612358                                                              15    9605
NP_997234                                                              15    9605
>NP_001274103
          Length = 1582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+RIS
Sbjct: 832 GGQRQRIS 839
>NP_000343
          Length = 1581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+RIS
Sbjct: 831 GGQRQRIS 838
>NP_689618
          Length = 988

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           G QR+R+S+
Sbjct: 881 GLQRRRVSS 889
>NP_036213
          Length = 640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AQRKRIS 8
           AQRKR+S
Sbjct: 574 AQRKRLS 580
>NP_150229
          Length = 1359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+RIS
Sbjct: 605 GGQRQRIS 612
>NP_005679
          Length = 1437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+RIS
Sbjct: 687 GGQRQRIS 694
>XP_006718349
          Length = 1646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+RIS
Sbjct: 831 GGQRQRIS 838
>XP_006714638
          Length = 585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AQRKRIS 8
           AQRKR+S
Sbjct: 519 AQRKRLS 525
>XP_006714637
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AQRKRIS 8
           AQRKR+S
Sbjct: 574 AQRKRLS 580
>XP_005248487
          Length = 947

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           G QR+R+S+
Sbjct: 840 GLQRRRVSS 848
>XP_005247116
          Length = 1437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+RIS
Sbjct: 687 GGQRQRIS 694
>XP_005247115
          Length = 1437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+RIS
Sbjct: 687 GGQRQRIS 694
>XP_005276063
          Length = 225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           GA+RKR +A
Sbjct: 115 GARRKRAAA 123
>NP_005912
          Length = 1512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 268 GVRRKRVS 275
>NP_569079
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GAQRKRIS 8
          GA+R+R+S
Sbjct: 68 GAKRRRLS 75
>NP_064520
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GAQRKRIS 8
          GA+R+R+S
Sbjct: 68 GAKRRRLS 75
>NP_004906
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 219 GGQRKRLA 226
>NP_997511
          Length = 644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 197 GGQRKRLA 204
>NP_058198
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 219 GGQRKRLA 226
>NP_997512
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 216 GGQRKRLA 223
>NP_997510
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 221 GGQRKRLA 228
>NP_997057
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 230 GGQRKRLA 237
>NP_003777
          Length = 1527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+R+S
Sbjct: 753 GGQRQRVS 760
>NP_065166
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G+QR R+S
Sbjct: 240 GSQRSRVS 247
>XP_006723895
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G+QR R+S
Sbjct: 240 GSQRSRVS 247
>XP_005257820
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QR+R+S
Sbjct: 689 GGQRQRVS 696
>XP_005249289
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GAQRKRIS 8
          GA+R+R+S
Sbjct: 68 GAKRRRLS 75
>XP_005248577
          Length = 1349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 105 GVRRKRVS 112
>XP_005248576
          Length = 1375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 131 GVRRKRVS 138
>NP_001135977
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 203 GGQRKRLA 210
>NP_071452
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G QRKR++
Sbjct: 203 GGQRKRLA 210
>NP_000855
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QRKRISA 9
           +RKRISA
Sbjct: 287 ERKRISA 293
>NP_000483
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GAQRKRIS 8
           G QR RIS
Sbjct: 550 GGQRARIS 557
>NP_060720
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 565 GKKRKRVS 572
>NP_443148
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AQRKRISA 9
           AQR+R+S+
Sbjct: 654 AQRRRLSS 661
>NP_001166033
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 541 GKKRKRVS 548
>NP_001012661
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GAQRKRIS 8
          GAQ +R+S
Sbjct: 41 GAQSRRVS 48
>XP_005258122
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GAQRKRISA 9
          GA+R+R+ A
Sbjct: 85 GAKRRRLRA 93
>XP_006722225
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           GA+R+R+ A
Sbjct: 176 GAKRRRLRA 184
>XP_005258120
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           GA+R+R+ A
Sbjct: 176 GAKRRRLRA 184
>XP_005258121
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           GA+R+R+ A
Sbjct: 176 GAKRRRLRA 184
>XP_005258119
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           GA+R+R+ A
Sbjct: 176 GAKRRRLRA 184
>XP_006721725
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AQRKRISA 9
           AQR+R+S+
Sbjct: 588 AQRRRLSS 595
>XP_006721723
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AQRKRISA 9
           AQR+R+S+
Sbjct: 655 AQRRRLSS 662
>XP_006716420
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 565 GKKRKRVS 572
>XP_006716419
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 565 GKKRKRVS 572
>XP_006715905
          Length = 1588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GAQRKRIS 8
           G QR RIS
Sbjct: 658 GGQRARIS 665
>NP_001138631
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAQRKRIS 8
           G +RKR+S
Sbjct: 544 GKKRKRVS 551
>NP_612358
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GAQRKRISA 9
           GA+R+R+ A
Sbjct: 201 GAKRRRLRA 209
>NP_997234
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GAQRKRI 7
           GAQR+R+
Sbjct: 104 GAQRERL 110
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.124    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 448,540
Number of extensions: 886
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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