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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              18    1935
XP_006714104                                                           18    1935
XP_005265800                                                           18    1935
XP_006714103                                                           18    1935
XP_006714102                                                           18    1935
NP_001276049                                                           17    4312
NP_001276048                                                           17    4312
NP_001276050                                                           17    4312
NP_115602                                                              17    4312
XP_005251669                                                           17    4312
XP_005251668                                                           17    4312
XP_005251666                                                           17    4312
XP_005251665                                                           17    4312
NP_004663                                                              16    5631
XP_005246086                                                           16    5631
NP_071379                                                              15    9605
XP_005260849                                                           15    9605
NP_942093                                                              15    9605

>NP_006197
          Length = 1089

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FVMVLEVSS 9
          FV VLEVSS
Sbjct: 81 FVTVLEVSS 89



>XP_006714104
          Length = 832

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FVMVLEVSS 9
           FV VLEVSS
Sbjct: 106 FVTVLEVSS 114



>XP_005265800
          Length = 1089

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FVMVLEVSS 9
          FV VLEVSS
Sbjct: 81 FVTVLEVSS 89



>XP_006714103
          Length = 1111

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FVMVLEVSS 9
           FV VLEVSS
Sbjct: 103 FVTVLEVSS 111



>XP_006714102
          Length = 1114

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FVMVLEVSS 9
           FV VLEVSS
Sbjct: 106 FVTVLEVSS 114



>NP_001276049
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>NP_001276048
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>NP_001276050
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>NP_115602
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>XP_005251669
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>XP_005251668
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>XP_005251666
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>XP_005251665
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           VM++EVSS
Sbjct: 152 VMIIEVSS 159



>NP_004663
          Length = 1288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           V+VLEVSS
Sbjct: 115 VVVLEVSS 122



>XP_005246086
          Length = 1280

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VMVLEVSS 9
           V+VLEVSS
Sbjct: 115 VVVLEVSS 122



>NP_071379
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FVMVLE 6
           FVMVLE
Sbjct: 359 FVMVLE 364



>XP_005260849
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FVMVLE 6
           FVMVLE
Sbjct: 170 FVMVLE 175



>NP_942093
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FVMVLE 6
           FVMVLE
Sbjct: 359 FVMVLE 364



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.136    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 220,237
Number of extensions: 112
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)