Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_055259                                                              17    2528
NP_001273343                                                           17    2528
NP_001180401                                                           17    4312
NP_001180400                                                           17    4312
NP_001180402                                                           17    4312
NP_001014986                                                           17    4312
NP_004467                                                              17    4312
NP_001171536                                                           17    4312
NP_000379                                                              17    4312
NP_710163                                                              17    4312
XP_006718839                                                           17    4312
XP_005252896                                                           17    4312
XP_005247894                                                           17    4312
XP_006713853                                                           17    4312
XP_005247893                                                           17    4312
XP_006713852                                                           17    4312
NP_055211                                                              16    5631
NP_005868                                                              16    5631
NP_001005409                                                           16    5631
NP_542198                                                              16    5631
NP_003213                                                              16    7355
NP_001091846                                                           16    7355
NP_001010890                                                           16    7355
NP_001009611                                                           16    7355
NP_001139816                                                           16    7355
NP_001013425                                                           16    7355
NP_077816                                                              16    7355
NP_695001                                                              16    7355
NP_542138                                                              16    7355
XP_006726395                                                           16    7355
XP_005276181                                                           16    7355
XP_005276180                                                           16    7355
XP_005276179                                                           16    7355
XP_006725019                                                           16    7355
XP_006725018                                                           16    7355
XP_006723606                                                           16    7355
XP_006720682                                                           16    7355
XP_005268318                                                           16    7355
XP_006711146                                                           16    7355
XP_006711145                                                           16    7355
XP_006711143                                                           16    7355
XP_006710315                                                           16    7355
NP_001010889                                                           16    7355
NP_001034612                                                           15    9605
NP_000070                                                              15    9605
NP_001243034                                                           15    9605
NP_003383                                                              15    9605
NP_002717                                                              15    9605
NP_787036                                                              15    9605
NP_787034                                                              15    9605
NP_787033                                                              15    9605
NP_001257620                                                           15    9605
NP_066363                                                              15    9605
XP_006723899                                                           15    9605
XP_006723641                                                           15    9605
XP_005267101                                                           15    9605
XP_006713387                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    TEIISQFT 9
            TEIISQFT
Sbjct: 2818 TEIISQFT 2825
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    TEIISQFT 9
            TEIISQFT
Sbjct: 2810 TEIISQFT 2817
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    TEIISQFT 9
            TEIISQFT
Sbjct: 2771 TEIISQFT 2778
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    TEIISQFT 9
            TEIISQFT
Sbjct: 2850 TEIISQFT 2857
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    TEIISQFT 9
            TEIISQFT
Sbjct: 2863 TEIISQFT 2870
>NP_055259
          Length = 666

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTEIISQFT 9
          FTE I Q+T
Sbjct: 55 FTEFIEQYT 63
>NP_001273343
          Length = 667

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTEIISQFT 9
          FTE I Q+T
Sbjct: 55 FTEFIEQYT 63
>NP_001180401
          Length = 704

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 624 FTEIASKFS 632
>NP_001180400
          Length = 735

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 624 FTEIASKFS 632
>NP_001180402
          Length = 442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 331 FTEIASKFS 339
>NP_001014986
          Length = 719

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 639 FTEIASKFS 647
>NP_004467
          Length = 750

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 639 FTEIASKFS 647
>NP_001171536
          Length = 1088

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FTEIISQFT 9
           F+E+ISQ++
Sbjct: 239 FSELISQYS 247
>NP_000379
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FTEIISQFT 9
           F+E+ISQ++
Sbjct: 239 FSELISQYS 247
>NP_710163
          Length = 442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 331 FTEIASKFS 339
>XP_006718839
          Length = 733

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 622 FTEIASKFS 630
>XP_005252896
          Length = 582

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FTEI S+F+
Sbjct: 471 FTEIASKFS 479
>XP_005247894
          Length = 917

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  FTEIISQFT 9
          F+E+ISQ++
Sbjct: 78 FSELISQYS 86
>XP_006713853
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FTEIISQFT 9
           F+E+ISQ++
Sbjct: 239 FSELISQYS 247
>XP_005247893
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FTEIISQFT 9
           F+E+ISQ++
Sbjct: 239 FSELISQYS 247
>XP_006713852
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FTEIISQFT 9
           F+E+ISQ++
Sbjct: 239 FSELISQYS 247
>NP_055211
          Length = 854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FTEIISQF 8
           + EI+SQF
Sbjct: 258 YVEIVSQF 265
>NP_005868
          Length = 793

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FT+++ Q+T
Sbjct: 208 FTKLVEQYT 216
>NP_001005409
          Length = 728

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FT+++ Q+T
Sbjct: 143 FTKLVEQYT 151
>NP_542198
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FTEIISQF 8
           + EI+SQF
Sbjct: 233 YVEIVSQF 240
>NP_003213
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FTEIISQ 7
           FTE++SQ
Sbjct: 362 FTELLSQ 368
>NP_001091846
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>NP_001010890
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>NP_001009611
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>NP_001139816
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>NP_001013425
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 255 EIVTQFT 261
>NP_077816
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FTEIISQF 8
           F+E++S+F
Sbjct: 215 FSELVSEF 222
>NP_695001
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FTEIISQF 8
           F EII QF
Sbjct: 302 FREIIDQF 309
>NP_542138
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FTEIISQF 8
           F EII QF
Sbjct: 301 FREIIDQF 308
>XP_006726395
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 256 EIVTQFT 262
>XP_005276181
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_005276180
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_005276179
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_006725019
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_006725018
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_006723606
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FTEIISQF 8
           F EII QF
Sbjct: 249 FREIIDQF 256
>XP_006720682
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FTEIISQF 8
           F+E++S+F
Sbjct: 215 FSELVSEF 222
>XP_005268318
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FTEIISQF 8
           F+E++S+F
Sbjct: 215 FSELVSEF 222
>XP_006711146
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_006711145
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_006711143
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>XP_006710315
          Length = 287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 257 EIVTQFT 263
>NP_001010889
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISQFT 9
           EI++QFT
Sbjct: 255 EIVTQFT 261
>NP_001034612
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FT+++ Q+T
Sbjct: 150 FTKVLLQYT 158
>NP_000070
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FTEIISQFT 9
           FT+++ Q+T
Sbjct: 125 FTKVLLQYT 133
>NP_001243034
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TEIISQF 8
           TEI+ QF
Sbjct: 356 TEIVDQF 362
>NP_003383
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TEIISQF 8
           TEI+ QF
Sbjct: 371 TEIVDQF 377
>NP_002717
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TEIISQFT 9
           TEI  QFT
Sbjct: 392 TEIFYQFT 399
>NP_787036
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEIISQFT 9
           TE++ QFT
Sbjct: 396 TEMLRQFT 403
>NP_787034
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEIISQFT 9
           TE++ QFT
Sbjct: 396 TEMLRQFT 403
>NP_787033
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEIISQFT 9
           TE++ QFT
Sbjct: 449 TEMLRQFT 456
>NP_001257620
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEIISQFT 9
           TE++ QFT
Sbjct: 449 TEMLRQFT 456
>NP_066363
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEIISQFT 9
           +EI+ QFT
Sbjct: 686 SEILKQFT 693
>XP_006723899
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEIISQFT 9
           +EI+ QFT
Sbjct: 686 SEILKQFT 693
>XP_006723641
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TEIISQFT 9
           TE++ QFT
Sbjct: 449 TEMLRQFT 456
>XP_005267101
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TEIISQFT 9
           TEI  QFT
Sbjct: 392 TEIFYQFT 399
>XP_006713387
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TEIISQF 8
           TEI+ QF
Sbjct: 356 TEIVDQF 362
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.140    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 359,975
Number of extensions: 658
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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