Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              20     390
NP_001091680                                                           20     390
NP_001091679                                                           20     390
XP_006713048                                                           20     390
XP_006713047                                                           20     390
XP_006713046                                                           20     390
XP_005264943                                                           20     390
NP_004303                                                              16    7355
XP_006724714                                                           16    7355
NP_001018125                                                           15    9605
NP_149075                                                              15    9605
NP_075384                                                              15    9605
XP_005276286                                                           15    9605
XP_005277590                                                           15    9605
XP_005265698                                                           15    9605
XP_005265004                                                           15    9605
XP_006713088                                                           15    9605
XP_006713087                                                           15    9605
XP_005265003                                                           15    9605
XP_006713086                                                           15    9605
XP_006713085                                                           15    9605
XP_006713084                                                           15    9605
XP_005276004                                                           15    9605
NP_037377                                                              15    9605
>NP_001895
          Length = 781

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FSQSFAQEQ 9
          FSQSF QEQ
Sbjct: 70 FSQSFTQEQ 78
>NP_001091680
          Length = 781

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FSQSFAQEQ 9
          FSQSF QEQ
Sbjct: 70 FSQSFTQEQ 78
>NP_001091679
          Length = 781

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FSQSFAQEQ 9
          FSQSF QEQ
Sbjct: 70 FSQSFTQEQ 78
>XP_006713048
          Length = 720

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FSQSFAQEQ 9
          FSQSF QEQ
Sbjct: 70 FSQSFTQEQ 78
>XP_006713047
          Length = 774

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FSQSFAQEQ 9
          FSQSF QEQ
Sbjct: 63 FSQSFTQEQ 71
>XP_006713046
          Length = 774

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FSQSFAQEQ 9
          FSQSF QEQ
Sbjct: 63 FSQSFTQEQ 71
>XP_005264943
          Length = 781

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FSQSFAQEQ 9
          FSQSF QEQ
Sbjct: 70 FSQSFTQEQ 78
>NP_004303
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSQSFA 6
           FSQSFA
Sbjct: 265 FSQSFA 270
>XP_006724714
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSQSFA 6
           FSQSFA
Sbjct: 220 FSQSFA 225
>NP_001018125
          Length = 1451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 704 FSQDFAKD 711
>NP_149075
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 704 FSQDFAKD 711
>NP_075384
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SQSFAQEQ 9
           SQS+ +EQ
Sbjct: 156 SQSYVEEQ 163
>XP_005276286
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 251 FSQDFAKD 258
>XP_005277590
          Length = 900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 451 FSQDFAKD 458
>XP_005265698
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 235 FSQDFAKD 242
>XP_005265004
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FSQSFAQE 8
          FSQ FA++
Sbjct: 39 FSQDFAKD 46
>XP_006713088
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 615 FSQDFAKD 622
>XP_006713087
          Length = 1432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 704 FSQDFAKD 711
>XP_005265003
          Length = 1451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 704 FSQDFAKD 711
>XP_006713086
          Length = 1458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 704 FSQDFAKD 711
>XP_006713085
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 704 FSQDFAKD 711
>XP_006713084
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 704 FSQDFAKD 711
>XP_005276004
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSQSFAQE 8
           FSQ FA++
Sbjct: 242 FSQDFAKD 249
>NP_037377
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FSQSFAQE 8
           FS+ F QE
Sbjct: 429 FSEDFGQE 436
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.115    0.285 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 444,821
Number of extensions: 785
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package