Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              20     390
NP_653267                                                              17    4312
NP_005492                                                              16    5631
NP_079350                                                              16    5631
NP_002195                                                              16    5631
XP_005257365                                                           16    5631
XP_006714380                                                           16    5631
XP_006714379                                                           16    5631
XP_006714378                                                           16    5631
XP_006714377                                                           16    5631
NP_872384                                                              16    7355
NP_001265473                                                           16    7355
NP_000057                                                              16    7355
NP_001265472                                                           16    7355
XP_005248250                                                           16    7355
XP_005245152                                                           16    7355
XP_005271223                                                           16    7355
XP_006710936                                                           16    7355
NP_444270                                                              16    7355
NP_001175                                                              15    9605
NP_996895                                                              15    9605
NP_036227                                                              15    9605
NP_056127                                                              15    9605
NP_002421                                                              15    9605
NP_115270                                                              15    9605
XP_006717827                                                           15    9605
XP_006717826                                                           15    9605
XP_006714407                                                           15    9605
XP_006714406                                                           15    9605
XP_006714405                                                           15    9605
XP_005263349                                                           15    9605
XP_005263348                                                           15    9605
XP_005263347                                                           15    9605
XP_005263346                                                           15    9605
XP_005263345                                                           15    9605
XP_005263344                                                           15    9605
XP_005263343                                                           15    9605
XP_005263342                                                           15    9605
XP_005263341                                                           15    9605
XP_005263340                                                           15    9605
XP_005263339                                                           15    9605
>NP_004351
          Length = 882

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  FSLNTRFKV 9
          FSL+TRFKV
Sbjct: 69 FSLDTRFKV 77
>NP_653267
          Length = 4753

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LNTRFKV 9
            LN+RFKV
Sbjct: 1284 LNSRFKV 1290
>NP_005492
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FSLNTRFKV 9
          F+L+TRF V
Sbjct: 33 FNLDTRFLV 41
>NP_079350
          Length = 4012

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FSLNTRFKV 9
            +SLNT F++
Sbjct: 3660 YSLNTEFQL 3668
>NP_002195
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FSLNTRFKV 9
          F+L+TRF V
Sbjct: 33 FNLDTRFLV 41
>XP_005257365
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FSLNTRFKV 9
          F+L+TRF V
Sbjct: 33 FNLDTRFLV 41
>XP_006714380
          Length = 3897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FSLNTRFKV 9
            +SLNT F++
Sbjct: 3545 YSLNTEFQL 3553
>XP_006714379
          Length = 3936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FSLNTRFKV 9
            +SLNT F++
Sbjct: 3584 YSLNTEFQL 3592
>XP_006714378
          Length = 3965

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FSLNTRFKV 9
            +SLNT F++
Sbjct: 3613 YSLNTEFQL 3621
>XP_006714377
          Length = 4010

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FSLNTRFKV 9
            +SLNT F++
Sbjct: 3658 YSLNTEFQL 3666
>NP_872384
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLNTRFK 8
           SLN RFK
Sbjct: 185 SLNIRFK 191
>NP_001265473
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSLNTRFK 8
           + LNTRF+
Sbjct: 142 YILNTRFR 149
>NP_000057
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSLNTRFK 8
           + LNTRF+
Sbjct: 204 YILNTRFR 211
>NP_001265472
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSLNTRFK 8
           + LNTRF+
Sbjct: 152 YILNTRFR 159
>XP_005248250
          Length = 1074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLNTRFKV 9
           S+N++FKV
Sbjct: 120 SVNSKFKV 127
>XP_005245152
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLNTRFK 8
           SLN RFK
Sbjct: 185 SLNIRFK 191
>XP_005271223
          Length = 628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSLNTRFK 8
           + LNTRF+
Sbjct: 241 YILNTRFR 248
>XP_006710936
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FSLNTRFK 8
           + LNTRF+
Sbjct: 243 YILNTRFR 250
>NP_444270
          Length = 1074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLNTRFKV 9
           S+N++FKV
Sbjct: 120 SVNSKFKV 127
>NP_001175
          Length = 2644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    LNTRFK 8
            LNTR+K
Sbjct: 1458 LNTRYK 1463
>NP_996895
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLNTRFKV 9
           SLN +FK+
Sbjct: 372 SLNIQFKI 379
>NP_036227
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLNTRFKV 9
           SLN +FK+
Sbjct: 372 SLNIQFKI 379
>NP_056127
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
>NP_002421
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  SLNTRFK 8
          S+NT FK
Sbjct: 29 SMNTHFK 35
>NP_115270
          Length = 818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FSLNTRFKV 9
           FSL T+F V
Sbjct: 808 FSLPTQFSV 816
>XP_006717827
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLNTRFKV 9
           SLN +FK+
Sbjct: 372 SLNIQFKI 379
>XP_006717826
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLNTRFKV 9
           SLN +FK+
Sbjct: 372 SLNIQFKI 379
>XP_006714407
          Length = 5004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3154 YSLNLQFK 3161
>XP_006714406
          Length = 3680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
>XP_006714405
          Length = 4103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 2232 YSLNLQFK 2239
>XP_005263349
          Length = 4410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 2539 YSLNLQFK 2546
>XP_005263348
          Length = 4443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 2572 YSLNLQFK 2579
>XP_005263347
          Length = 4640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
>XP_005263346
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3112 YSLNLQFK 3119
>XP_005263345
          Length = 4991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
>XP_005263344
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
>XP_005263343
          Length = 5009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3138 YSLNLQFK 3145
>XP_005263342
          Length = 5025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3154 YSLNLQFK 3161
>XP_005263341
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
>XP_005263340
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
>XP_005263339
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FSLNTRFK 8
            +SLN +FK
Sbjct: 3155 YSLNLQFK 3162
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.142    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,103
Number of extensions: 552
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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