Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              21     229
XP_006718908                                                           21     229
XP_005271621                                                           21     229
XP_006718907                                                           21     229
XP_006718906                                                           21     229
XP_005271619                                                           21     229
XP_005271618                                                           21     229
NP_005925                                                              17    2528
XP_005259618                                                           17    2528
NP_002553                                                              17    3301
XP_006726484                                                           17    4312
XP_006715006                                                           17    4312
XP_006710234                                                           17    4312
NP_003176                                                              16    5631
NP_001175                                                              16    7355
NP_002464                                                              16    7355
NP_849172                                                              16    7355
NP_705618                                                              16    7355
NP_004289                                                              16    7355
NP_940928                                                              16    7355
NP_001265241                                                           16    7355
XP_005254964                                                           16    7355
XP_005254963                                                           16    7355
XP_005254962                                                           16    7355
XP_006720562                                                           16    7355
XP_006720561                                                           16    7355
NP_001185617                                                           15    9605
NP_001003680                                                           15    9605
NP_001185616                                                           15    9605
NP_002294                                                              15    9605
NP_001003679                                                           15    9605
NP_001185618                                                           15    9605
NP_078899                                                              15    9605
NP_775767                                                              15    9605
NP_056083                                                              15    9605
XP_005252426                                                           15    9605
XP_005252425                                                           15    9605
XP_005252424                                                           15    9605
XP_005247302                                                           15    9605
NP_839943                                                              15    9605
>NP_000042
          Length = 3056

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    FQEPMMALR 9
            FQEP+MALR
Sbjct: 2219 FQEPIMALR 2227
>XP_006718908
          Length = 1708

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FQEPMMALR 9
           FQEP+MALR
Sbjct: 871 FQEPIMALR 879
>XP_005271621
          Length = 2708

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    FQEPMMALR 9
            FQEP+MALR
Sbjct: 1871 FQEPIMALR 1879
>XP_006718907
          Length = 3050

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    FQEPMMALR 9
            FQEP+MALR
Sbjct: 2213 FQEPIMALR 2221
>XP_006718906
          Length = 3056

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    FQEPMMALR 9
            FQEP+MALR
Sbjct: 2219 FQEPIMALR 2227
>XP_005271619
          Length = 3056

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    FQEPMMALR 9
            FQEP+MALR
Sbjct: 2219 FQEPIMALR 2227
>XP_005271618
          Length = 3056

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    FQEPMMALR 9
            FQEP+MALR
Sbjct: 2219 FQEPIMALR 2227
>NP_005925
          Length = 559

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           F+EP MAL+
Sbjct: 251 FKEPKMALK 259
>XP_005259618
          Length = 517

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           F+EP MAL+
Sbjct: 209 FKEPKMALK 217
>NP_002553
          Length = 595

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FQEPMMAL 8
           +QEP++AL
Sbjct: 529 YQEPLLAL 536
>XP_006726484
          Length = 213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FQEPMMA 7
           FQEPM A
Sbjct: 160 FQEPMWA 166
>XP_006715006
          Length = 213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FQEPMMA 7
           FQEPM A
Sbjct: 160 FQEPMWA 166
>XP_006710234
          Length = 213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FQEPMMA 7
           FQEPM A
Sbjct: 160 FQEPMWA 166
>NP_003176
          Length = 1085

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QEPMMALR 9
           Q PM+ALR
Sbjct: 762 QTPMVALR 769
>NP_001175
          Length = 2644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QEPMMALR 9
            +EP++ALR
Sbjct: 1897 KEPILALR 1904
>NP_002464
          Length = 1960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FQEPMMALR 9
           FQE M A+R
Sbjct: 319 FQETMEAMR 327
>NP_849172
          Length = 1065

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FQEPMMAL 8
           FQ+P+M L
Sbjct: 649 FQDPVMEL 656
>NP_705618
          Length = 1391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FQEPMM 6
           FQ+PMM
Sbjct: 441 FQKPMM 446
>NP_004289
          Length = 1332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FQEPMM 6
           FQ+PMM
Sbjct: 382 FQKPMM 387
>NP_940928
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           F EP MAL
Sbjct: 199 FPEPSMAL 206
>NP_001265241
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FQEPMM 6
           FQ+PMM
Sbjct: 441 FQKPMM 446
>XP_005254964
          Length = 679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           F EP MAL
Sbjct: 199 FPEPSMAL 206
>XP_005254963
          Length = 679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           F EP MAL
Sbjct: 199 FPEPSMAL 206
>XP_005254962
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           F EP MAL
Sbjct: 211 FPEPSMAL 218
>XP_006720562
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           F EP MAL
Sbjct: 294 FPEPSMAL 301
>XP_006720561
          Length = 774

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           F EP MAL
Sbjct: 294 FPEPSMAL 301
>NP_001185617
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           FQ P+M+++
Sbjct: 222 FQSPLMSVQ 230
>NP_001003680
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           FQ P+M+++
Sbjct: 222 FQSPLMSVQ 230
>NP_001185616
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           FQ P+M+++
Sbjct: 222 FQSPLMSVQ 230
>NP_002294
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           FQ P+M+++
Sbjct: 222 FQSPLMSVQ 230
>NP_001003679
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           FQ P+M+++
Sbjct: 222 FQSPLMSVQ 230
>NP_001185618
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FQEPMMALR 9
           FQ P+M+++
Sbjct: 222 FQSPLMSVQ 230
>NP_078899
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FQEPMMAL 8
           F +P+MAL
Sbjct: 137 FLQPLMAL 144
>NP_775767
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FQEPMMALR 9
           FQE  +ALR
Sbjct: 293 FQERRLALR 301
>NP_056083
          Length = 2243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           FQ P MA+
Sbjct: 570 FQHPSMAI 577
>XP_005252426
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FQEPMMALR 9
           FQE  +ALR
Sbjct: 293 FQERRLALR 301
>XP_005252425
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FQEPMMALR 9
           FQE  +ALR
Sbjct: 293 FQERRLALR 301
>XP_005252424
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FQEPMMALR 9
           FQE  +ALR
Sbjct: 293 FQERRLALR 301
>XP_005247302
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FQEPMMAL 8
           FQ P MA+
Sbjct: 570 FQHPSMAI 577
>NP_839943
          Length = 1631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QEPMMALR 9
           Q+P +ALR
Sbjct: 317 QDPALALR 324
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.139    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 602,107
Number of extensions: 461
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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