Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121619                                                           18    1482
NP_000258                                                              18    1482
NP_001035957                                                           18    1482
XP_006721991                                                           18    1482
XP_006721990                                                           18    1482
XP_006721989                                                           18    1482
XP_005258041                                                           18    1482
XP_006721988                                                           18    1482
XP_006721987                                                           18    1482
XP_006721986                                                           18    1482
XP_005258040                                                           18    1482
XP_006721985                                                           18    1482
NP_872577                                                              17    4312
NP_000186                                                              17    4312
NP_001135817                                                           17    4312
NP_001135815                                                           17    4312
NP_001135816                                                           17    4312
XP_005269816                                                           17    4312
XP_005269815                                                           17    4312
XP_005269813                                                           17    4312
XP_005269814                                                           17    4312
XP_005269812                                                           17    4312
NP_004063                                                              17    4312
NP_001073922                                                           16    5631
NP_065996                                                              16    7355
XP_005270064                                                           16    7355
XP_005270062                                                           16    7355
XP_005270061                                                           16    7355
NP_001234928                                                           15    9605
NP_690590                                                              15    9605
NP_690591                                                              15    9605
NP_071744                                                              15    9605
NP_000161                                                              15    9605
NP_000126                                                              15    9605
NP_001243514                                                           15    9605
NP_001003794                                                           15    9605
NP_009214                                                              15    9605
NP_997247                                                              15    9605
NP_001018122                                                           15    9605
NP_001273096                                                           15    9605
NP_852466                                                              15    9605
NP_006181                                                              15    9605
NP_066919                                                              15    9605
NP_001003406                                                           15    9605
NP_003153                                                              15    9605
XP_006724411                                                           15    9605
XP_005256351                                                           15    9605
XP_006721230                                                           15    9605
XP_006718726                                                           15    9605
XP_006718725                                                           15    9605
XP_006718724                                                           15    9605
XP_006718723                                                           15    9605
XP_006718722                                                           15    9605
XP_005274235                                                           15    9605
XP_005274234                                                           15    9605
XP_006718721                                                           15    9605
XP_005270063                                                           15    9605
XP_005247151                                                           15    9605
XP_005247150                                                           15    9605
XP_005265160                                                           15    9605
XP_006713189                                                           15    9605
XP_005265159                                                           15    9605
XP_006712618                                                           15    9605
XP_005264576                                                           15    9605
NP_004203                                                              15    9605
NP_006840                                                              15    9605
>NP_001121619
          Length = 593

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>NP_000258
          Length = 2818

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>NP_001035957
          Length = 2839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_006721991
          Length = 1632

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_006721990
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_006721989
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_005258041
          Length = 2836

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_006721988
          Length = 2846

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_006721987
          Length = 2849

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_006721986
          Length = 2854

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 330 FLLVQSMVV 338
>XP_005258040
          Length = 2857

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>XP_006721985
          Length = 2867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLV SMVV
Sbjct: 343 FLLVQSMVV 351
>NP_872577
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLVHS ++
Sbjct: 210 FLLVHSKLL 218
>NP_000186
          Length = 700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLVHS ++
Sbjct: 210 FLLVHSKLL 218
>NP_001135817
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FLLVHSM 7
           FLL+H+M
Sbjct: 117 FLLIHNM 123
>NP_001135815
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FLLVHSM 7
           FLL+H+M
Sbjct: 117 FLLIHNM 123
>NP_001135816
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FLLVHSM 7
           FLL+H+M
Sbjct: 117 FLLIHNM 123
>XP_005269816
          Length = 577

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FLLVHSMVV 9
          FLLVHS ++
Sbjct: 87 FLLVHSKLL 95
>XP_005269815
          Length = 667

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLVHS ++
Sbjct: 210 FLLVHSKLL 218
>XP_005269813
          Length = 700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLVHS ++
Sbjct: 210 FLLVHSKLL 218
>XP_005269814
          Length = 700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLVHS ++
Sbjct: 210 FLLVHSKLL 218
>XP_005269812
          Length = 700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FLLVHSMVV 9
           FLLVHS ++
Sbjct: 210 FLLVHSKLL 218
>NP_004063
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FLLVHSM 7
           FLL+H+M
Sbjct: 115 FLLIHNM 121
>NP_001073922
          Length = 2190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLVHSMVV 9
            L+VH+MV+
Sbjct: 1165 LVVHAMVI 1172
>NP_065996
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FLLVHSMVV 9
            F+L H MVV
Sbjct: 1987 FILEHIMVV 1995
>XP_005270064
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLLVHSMVV 9
           F+L H MVV
Sbjct: 418 FILEHIMVV 426
>XP_005270062
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FLLVHSMVV 9
            F+L H MVV
Sbjct: 1987 FILEHIMVV 1995
>XP_005270061
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FLLVHSMVV 9
            F+L H MVV
Sbjct: 1987 FILEHIMVV 1995
>NP_001234928
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 140 LLVHSSLV 147
>NP_690590
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 112 LLVHSSLV 119
>NP_690591
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 112 LLVHSSLV 119
>NP_071744
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 112 LLVHSSLV 119
>NP_000161
          Length = 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LVHSMV 8
           LVHSM+
Sbjct: 548 LVHSMI 553
>NP_000126
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           +LL HSM
Sbjct: 154 YLLAHSM 160
>NP_001243514
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           FLL HSM
Sbjct: 127 FLLGHSM 133
>NP_001003794
          Length = 303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           FLL HSM
Sbjct: 117 FLLGHSM 123
>NP_009214
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           FLL HSM
Sbjct: 127 FLLGHSM 133
>NP_997247
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LLVHSMVV 9
           LL+HS+++
Sbjct: 263 LLIHSVLI 270
>NP_001018122
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           +LL HSM
Sbjct: 154 YLLAHSM 160
>NP_001273096
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           +LL HSM
Sbjct: 154 YLLAHSM 160
>NP_852466
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FLLVHSMV 8
           FLL+H  V
Sbjct: 776 FLLIHQRV 783
>NP_006181
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   FLLVHSM 7
           FLL+H++
Sbjct: 389 FLLIHNL 395
>NP_066919
          Length = 2223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    LLVHSM 7
            LL+HSM
Sbjct: 1478 LLIHSM 1483
>NP_001003406
          Length = 2188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    LLVHSM 7
            LL+HSM
Sbjct: 1443 LLIHSM 1448
>NP_003153
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LVHSMV 8
           L+HSMV
Sbjct: 698 LIHSMV 703
>XP_006724411
          Length = 1528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LLVHSM 7
           LL+HSM
Sbjct: 783 LLIHSM 788
>XP_005256351
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           +LL HSM
Sbjct: 154 YLLAHSM 160
>XP_006721230
          Length = 1412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           +LL HSM
Sbjct: 154 YLLAHSM 160
>XP_006718726
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LLVHSMVV 9
          LLVHS +V
Sbjct: 67 LLVHSSLV 74
>XP_006718725
          Length = 203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LLVHSMVV 9
          LLVHS +V
Sbjct: 67 LLVHSSLV 74
>XP_006718724
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 95  LLVHSSLV 102
>XP_006718723
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 95  LLVHSSLV 102
>XP_006718722
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 140 LLVHSSLV 147
>XP_005274235
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 140 LLVHSSLV 147
>XP_005274234
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 140 LLVHSSLV 147
>XP_006718721
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLVHSMVV 9
           LLVHS +V
Sbjct: 140 LLVHSSLV 147
>XP_005270063
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FLLVHSMVV 9
            F+L H MV+
Sbjct: 1987 FILEHIMVI 1995
>XP_005247151
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  FLLVHSM 7
          FLL HSM
Sbjct: 91 FLLGHSM 97
>XP_005247150
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  FLLVHSM 7
          FLL HSM
Sbjct: 91 FLLGHSM 97
>XP_005265160
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FLLVHSMV 8
           FLL+H  V
Sbjct: 571 FLLIHQRV 578
>XP_006713189
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FLLVHSMV 8
           FLL+H  V
Sbjct: 764 FLLIHQRV 771
>XP_005265159
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FLLVHSMV 8
           FLL+H  V
Sbjct: 776 FLLIHQRV 783
>XP_006712618
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   FLLVHSM 7
           FLL+H++
Sbjct: 389 FLLIHNL 395
>XP_005264576
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LVHSMV 8
           L+HSMV
Sbjct: 661 LIHSMV 666
>NP_004203
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLLVHSMV 8
           F+LVHS +
Sbjct: 116 FVLVHSFL 123
>NP_006840
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FLLVHSM 7
           FL+ HSM
Sbjct: 250 FLVTHSM 256
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.352    0.152    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 464,474
Number of extensions: 586
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

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