Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001191397                                                           16    7355
NP_001139281                                                           16    7355
NP_001091872                                                           16    7355
NP_001070654                                                           16    7355
NP_005867                                                              16    7355
NP_079005                                                              16    7355
NP_065778                                                              16    7355
XP_005272736                                                           16    7355
XP_005272735                                                           16    7355
XP_005272734                                                           16    7355
XP_005261178                                                           16    7355
XP_006723449                                                           16    7355
XP_006712257                                                           16    7355
XP_006712255                                                           16    7355
XP_005246295                                                           16    7355
XP_006712253                                                           16    7355
XP_006712252                                                           16    7355
XP_005246294                                                           16    7355
XP_006712251                                                           16    7355
XP_005246293                                                           16    7355
XP_005246292                                                           16    7355
XP_006712250                                                           16    7355
NP_001248357                                                           15    9605
NP_663731                                                              15    9605
NP_001248356                                                           15    9605
NP_001074419                                                           15    9605
NP_001074248                                                           15    9605
NP_203693                                                              15    9605
NP_065696                                                              15    9605
NP_004681                                                              15    9605
XP_006723286                                                           15    9605
XP_006723285                                                           15    9605
XP_005259006                                                           15    9605
XP_005259005                                                           15    9605
XP_005256712                                                           15    9605
XP_006712256                                                           15    9605
XP_005246298                                                           15    9605
XP_005246297                                                           15    9605
XP_005246299                                                           15    9605
XP_005246296                                                           15    9605
XP_006712254                                                           15    9605
XP_006711938                                                           15    9605
XP_006711937                                                           15    9605
XP_006711936                                                           15    9605
XP_006711935                                                           15    9605
XP_006711934                                                           15    9605
XP_006711933                                                           15    9605
XP_006711932                                                           15    9605
NP_002437                                                              15    9605
>NP_001191397
          Length = 995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  KLRRGP 9
          +LRRGP
Sbjct: 51 RLRRGP 56
>NP_001139281
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KLRRGP 9
            +LRRGP
Sbjct: 1985 RLRRGP 1990
>NP_001091872
          Length = 1066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LLKLRRG 8
           ++KLRRG
Sbjct: 636 IIKLRRG 642
>NP_001070654
          Length = 2003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KLRRGP 9
            +LRRGP
Sbjct: 1952 RLRRGP 1957
>NP_005867
          Length = 3267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 669 RLRRGP 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3222 YLMKLRR 3228
>NP_079005
          Length = 1995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KLRRGP 9
            +LRRGP
Sbjct: 1944 RLRRGP 1949
>NP_065778
          Length = 1066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LLKLRRG 8
           ++KLRRG
Sbjct: 636 IIKLRRG 642
>XP_005272736
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  KLRRGP 9
          +LRRGP
Sbjct: 51 RLRRGP 56
>XP_005272735
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  KLRRGP 9
          +LRRGP
Sbjct: 51 RLRRGP 56
>XP_005272734
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  KLRRGP 9
          +LRRGP
Sbjct: 51 RLRRGP 56
>XP_005261178
          Length = 1066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LLKLRRG 8
           ++KLRRG
Sbjct: 636 IIKLRRG 642
>XP_006723449
          Length = 2003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KLRRGP 9
            +LRRGP
Sbjct: 1952 RLRRGP 1957
>XP_006712257
          Length = 1718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 669 RLRRGP 674
>XP_006712255
          Length = 2622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 669 RLRRGP 674
>XP_005246295
          Length = 3114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 516 RLRRGP 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3069 YLMKLRR 3075
>XP_006712253
          Length = 3117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 519 RLRRGP 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3072 YLMKLRR 3078
>XP_006712252
          Length = 3163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 565 RLRRGP 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3118 YLMKLRR 3124
>XP_005246294
          Length = 3173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 575 RLRRGP 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3128 YLMKLRR 3134
>XP_006712251
          Length = 3176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 578 RLRRGP 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3131 YLMKLRR 3137
>XP_005246293
          Length = 3206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 669 RLRRGP 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3161 YLMKLRR 3167
>XP_005246292
          Length = 3208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 610 RLRRGP 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3163 YLMKLRR 3169
>XP_006712250
          Length = 3248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLRRGP 9
           +LRRGP
Sbjct: 650 RLRRGP 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 3203 YLMKLRR 3209
>NP_001248357
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 723 LKLKNGP 729
>NP_663731
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 638 LKLKNGP 644
>NP_001248356
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 644 LKLKNGP 650
>NP_001074419
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FLLKLRR 7
           FLL LRR
Sbjct: 797 FLLNLRR 803
>NP_001074248
          Length = 1063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FLLKLRR 7
           FLL LRR
Sbjct: 816 FLLNLRR 822
>NP_203693
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FLLKLRR 7
           FLL LRR
Sbjct: 781 FLLNLRR 787
>NP_065696
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  LLKLRRGP 9
          L KLR GP
Sbjct: 73 LSKLRSGP 80
>NP_004681
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLKLRRGP 9
           ++KL RGP
Sbjct: 985 IIKLCRGP 992
>XP_006723286
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  LLKLRRG 8
          LLKLR G
Sbjct: 34 LLKLREG 40
>XP_006723285
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LLKLRRG 8
           LLKLR G
Sbjct: 130 LLKLREG 136
>XP_005259006
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LLKLRRG 8
           LLKLR G
Sbjct: 464 LLKLREG 470
>XP_005259005
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LLKLRRG 8
           LLKLR G
Sbjct: 464 LLKLREG 470
>XP_005256712
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FLLKLRR 7
           FLL LRR
Sbjct: 792 FLLNLRR 798
>XP_006712256
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 2373 YLMKLRR 2379
>XP_005246298
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 2373 YLMKLRR 2379
>XP_005246297
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 2373 YLMKLRR 2379
>XP_005246299
          Length = 2480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 2435 YLMKLRR 2441
>XP_005246296
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 2430 YLMKLRR 2436
>XP_006712254
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FLLKLRR 7
            +L+KLRR
Sbjct: 2430 YLMKLRR 2436
>XP_006711938
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 644 LKLKNGP 650
>XP_006711937
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 674 LKLKNGP 680
>XP_006711936
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 674 LKLKNGP 680
>XP_006711935
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 674 LKLKNGP 680
>XP_006711934
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 674 LKLKNGP 680
>XP_006711933
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 680 LKLKNGP 686
>XP_006711932
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKLRRGP 9
           LKL+ GP
Sbjct: 687 LKLKNGP 693
>NP_002437
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LLKLRRG 8
           LLKLR G
Sbjct: 464 LLKLREG 470
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.165    0.518 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 628,560
Number of extensions: 971
Number of successful extensions: 58
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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