Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           21     229
NP_000240                                                              21     229
NP_001161089                                                           21     229
XP_005265218                                                           18    1482
NP_899200                                                              17    4312
NP_001186571                                                           17    4312
NP_919424                                                              17    4312
NP_002287                                                              17    4312
XP_006713547                                                           17    4312
XP_006713546                                                           17    4312
XP_005247135                                                           17    4312
XP_005247134                                                           17    4312
XP_005273182                                                           17    4312
XP_006716126                                                           16    5631
XP_005250566                                                           16    5631
XP_005250565                                                           16    5631
NP_001120829                                                           16    5631
NP_001120830                                                           16    5631
NP_065165                                                              16    5631
NP_079236                                                              16    7355
NP_705902                                                              16    7355
NP_705904                                                              16    7355
NP_149122                                                              16    7355
NP_683878                                                              16    7355
NP_783200                                                              16    7355
NP_683879                                                              16    7355
NP_001193884                                                           16    7355
NP_612189                                                              16    7355
NP_006769                                                              16    7355
NP_001269212                                                           16    7355
NP_542179                                                              16    7355
NP_001075042                                                           16    7355
XP_006724868                                                           16    7355
XP_005274706                                                           16    7355
XP_005274705                                                           16    7355
XP_006724867                                                           16    7355
XP_006723694                                                           16    7355
XP_005260892                                                           16    7355
XP_005260893                                                           16    7355
XP_005269959                                                           16    7355
XP_006713068                                                           16    7355
XP_006713067                                                           16    7355
XP_006713066                                                           16    7355
NP_004179                                                              15    9605
NP_001120688                                                           15    9605
NP_005254                                                              15    9605
NP_001120687                                                           15    9605
NP_002664                                                              15    9605
NP_001123554                                                           15    9605
NP_005989                                                              15    9605
NP_065753                                                              15    9605
NP_001364                                                              15    9605
XP_006717361                                                           15    9605
XP_006717360                                                           15    9605
XP_006716871                                                           15    9605
XP_006713269                                                           15    9605
XP_006711798                                                           15    9605
XP_005270806                                                           15    9605
>NP_001245200
          Length = 687

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FGNAVSREM 9
           FGNAVSRE+
Sbjct: 220 FGNAVSREL 228
>NP_000240
          Length = 756

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FGNAVSREM 9
           FGNAVSRE+
Sbjct: 220 FGNAVSREL 228
>NP_001161089
          Length = 658

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FGNAVSREM 9
           FGNAVSRE+
Sbjct: 122 FGNAVSREL 130
>XP_005265218
          Length = 687

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   FGNAVSR 7
           FGNAVSR
Sbjct: 220 FGNAVSR 226
>NP_899200
          Length = 1261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GNAVSREM 9
           GN VS+EM
Sbjct: 686 GNQVSKEM 693
>NP_001186571
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GNAVSREM 9
           GN VS+EM
Sbjct: 336 GNQVSKEM 343
>NP_919424
          Length = 615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FGNAVSR 7
           FGN++SR
Sbjct: 125 FGNSISR 131
>NP_002287
          Length = 615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FGNAVSR 7
           FGN++SR
Sbjct: 125 FGNSISR 131
>XP_006713547
          Length = 845

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GNAVSREM 9
           GN VS+EM
Sbjct: 245 GNQVSKEM 252
>XP_006713546
          Length = 919

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GNAVSREM 9
           GN VS+EM
Sbjct: 319 GNQVSKEM 326
>XP_005247135
          Length = 936

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GNAVSREM 9
           GN VS+EM
Sbjct: 336 GNQVSKEM 343
>XP_005247134
          Length = 1286

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GNAVSREM 9
           GN VS+EM
Sbjct: 686 GNQVSKEM 693
>XP_005273182
          Length = 573

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FGNAVSR 7
           FGN++SR
Sbjct: 125 FGNSISR 131
>XP_006716126
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGNAVS 6
           FGNAVS
Sbjct: 425 FGNAVS 430
>XP_005250566
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGNAVS 6
           FGNAVS
Sbjct: 468 FGNAVS 473
>XP_005250565
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGNAVS 6
           FGNAVS
Sbjct: 468 FGNAVS 473
>NP_001120829
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGNAVS 6
           FGNAVS
Sbjct: 468 FGNAVS 473
>NP_001120830
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGNAVS 6
           FGNAVS
Sbjct: 464 FGNAVS 469
>NP_065165
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGNAVS 6
           FGNAVS
Sbjct: 464 FGNAVS 469
>NP_079236
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 181 FGNMMSKE 188
>NP_705902
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 472 FGNMMSKE 479
>NP_705904
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 181 FGNMMSKE 188
>NP_149122
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           FG  VSRE
Sbjct: 161 FGGMVSRE 168
>NP_683878
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 497 FGNMMSKE 504
>NP_783200
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           FG  VSRE
Sbjct: 106 FGTIVSRE 113
>NP_683879
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 272 FGNMMSKE 279
>NP_001193884
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           FG  VSRE
Sbjct: 106 FGTIVSRE 113
>NP_612189
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 213 FGNMMSKE 220
>NP_006769
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           F NAV+RE
Sbjct: 444 FTNAVTRE 451
>NP_001269212
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           F N VSRE
Sbjct: 495 FANPVSRE 502
>NP_542179
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           F N VSRE
Sbjct: 494 FANPVSRE 501
>NP_001075042
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           F N VSRE
Sbjct: 495 FANPVSRE 502
>XP_006724868
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           F N VSRE
Sbjct: 472 FANPVSRE 479
>XP_005274706
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           F N VSRE
Sbjct: 473 FANPVSRE 480
>XP_005274705
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           F N VSRE
Sbjct: 495 FANPVSRE 502
>XP_006724867
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           F N VSRE
Sbjct: 495 FANPVSRE 502
>XP_006723694
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 181 FGNMMSKE 188
>XP_005260892
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 267 FGNMMSKE 274
>XP_005260893
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 322 FGNMMSKE 329
>XP_005269959
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FGN +S+E
Sbjct: 438 FGNMMSKE 445
>XP_006713068
          Length = 699

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           FG  VSRE
Sbjct: 106 FGTIVSRE 113
>XP_006713067
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           FG  VSRE
Sbjct: 106 FGTIVSRE 113
>XP_006713066
          Length = 1032

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FGNAVSRE 8
           FG  VSRE
Sbjct: 106 FGTIVSRE 113
>NP_004179
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FG+AVS E
Sbjct: 201 FGHAVSLE 208
>NP_001120688
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FG+AVS E
Sbjct: 293 FGHAVSLE 300
>NP_005254
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FG+AVS E
Sbjct: 293 FGHAVSLE 300
>NP_001120687
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FG+AVS E
Sbjct: 293 FGHAVSLE 300
>NP_002664
          Length = 2135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GNAVSREM 9
           G+AVSR++
Sbjct: 450 GSAVSRDL 457
>NP_001123554
          Length = 2135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GNAVSREM 9
           G+AVSR++
Sbjct: 450 GSAVSRDL 457
>NP_005989
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GNAVSREM 9
          GNA+ RE+
Sbjct: 63 GNAILREI 70
>NP_065753
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   FGNAVSREM 9
           FG  V RE+
Sbjct: 402 FGEGVEREL 410
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FGNAVSRE 8
            FG A++RE
Sbjct: 2181 FGGALNRE 2188
>XP_006717361
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FG+AVS E
Sbjct: 201 FGHAVSLE 208
>XP_006717360
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FG+AVS E
Sbjct: 201 FGHAVSLE 208
>XP_006716871
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   FGNAVSREM 9
           FG  V RE+
Sbjct: 402 FGEGVEREL 410
>XP_006713269
          Length = 2052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GNAVSREM 9
           G+AVSR++
Sbjct: 367 GSAVSRDL 374
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FGNAVSRE 8
            FG A++RE
Sbjct: 2203 FGGALNRE 2210
>XP_005270806
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGNAVSRE 8
           FG+AVS E
Sbjct: 293 FGHAVSLE 300
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.130    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 435,870
Number of extensions: 680
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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