Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              19     665
NP_002871                                                              19     665
XP_005250103                                                           19     665
XP_005250102                                                           19     665
XP_005265416                                                           19     665
XP_005265415                                                           19     665
XP_005265414                                                           19     665
XP_005265412                                                           19     665
NP_001243125                                                           18    1482
NP_001645                                                              18    1482
XP_006724592                                                           18    1482
NP_001252541                                                           16    5631
NP_057368                                                              16    5631
NP_996882                                                              16    5631
NP_705833                                                              16    5631
XP_006726572                                                           16    5631
XP_006726571                                                           16    5631
XP_006726570                                                           16    5631
XP_003960511                                                           16    5631
XP_006717414                                                           16    5631
XP_006710283                                                           16    5631
XP_006710282                                                           16    5631
NP_001265                                                              16    7355
NP_001231775                                                           16    7355
NP_001107593                                                           16    7355
NP_001107594                                                           16    7355
NP_001035351                                                           16    7355
NP_001035350                                                           16    7355
NP_212133                                                              16    7355
NP_940938                                                              16    7355
NP_001138888                                                           16    7355
XP_005259958                                                           16    7355
XP_005259957                                                           16    7355
XP_005259959                                                           16    7355
XP_005259956                                                           16    7355
XP_005259955                                                           16    7355
XP_006718822                                                           16    7355
XP_005262843                                                           16    7355
XP_005262842                                                           16    7355
NP_203519                                                              15    9605
NP_001219                                                              15    9605
NP_001073593                                                           15    9605
NP_203520                                                              15    9605
NP_001073594                                                           15    9605
NP_001810                                                              15    9605
NP_001182345                                                           15    9605
NP_004725                                                              15    9605
NP_001182344                                                           15    9605
NP_079489                                                              15    9605
NP_066022                                                              15    9605
XP_006723369                                                           15    9605
XP_006719956                                                           15    9605
XP_005266649                                                           15    9605
XP_005246951                                                           15    9605
XP_006712854                                                           15    9605
XP_005246949                                                           15    9605
XP_006712853                                                           15    9605
XP_005246948                                                           15    9605
XP_005246947                                                           15    9605
XP_005246945                                                           15    9605
XP_006712852                                                           15    9605
XP_005246946                                                           15    9605
XP_005246944                                                           15    9605
XP_005246943                                                           15    9605
XP_005246942                                                           15    9605
>NP_004324
          Length = 766

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 595 FGLATVKSR 603
>NP_002871
          Length = 648

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 487 FGLATVKSR 495
>XP_005250103
          Length = 758

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 595 FGLATVKSR 603
>XP_005250102
          Length = 767

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 595 FGLATVKSR 603
>XP_005265416
          Length = 534

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 373 FGLATVKSR 381
>XP_005265415
          Length = 567

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 406 FGLATVKSR 414
>XP_005265414
          Length = 615

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 454 FGLATVKSR 462
>XP_005265412
          Length = 648

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV SR
Sbjct: 487 FGLATVKSR 495
>NP_001243125
          Length = 609

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV +R
Sbjct: 451 FGLATVKTR 459
>NP_001645
          Length = 606

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV +R
Sbjct: 448 FGLATVKTR 456
>XP_006724592
          Length = 611

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   FGLATVNSR 9
           FGLATV +R
Sbjct: 453 FGLATVKTR 461
>NP_001252541
          Length = 2371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGLATVNS 8
           FGLA +NS
Sbjct: 129 FGLALLNS 136
>NP_057368
          Length = 2376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGLATVNS 8
           FGLA +NS
Sbjct: 129 FGLALLNS 136
>NP_996882
          Length = 1551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGLATVNS 8
           FGLA +NS
Sbjct: 129 FGLALLNS 136
>NP_705833
          Length = 2970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           GLATVN+
Sbjct: 247 GLATVNT 253
>XP_006726572
          Length = 2066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    FGLATVNS 8
            FG+AT+N+
Sbjct: 1416 FGVATLNT 1423
>XP_006726571
          Length = 3681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    FGLATVNS 8
            FG+AT+N+
Sbjct: 3072 FGVATLNT 3079
>XP_006726570
          Length = 3722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    FGLATVNS 8
            FG+AT+N+
Sbjct: 3072 FGVATLNT 3079
>XP_003960511
          Length = 3722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    FGLATVNS 8
            FG+AT+N+
Sbjct: 3072 FGVATLNT 3079
>XP_006717414
          Length = 5100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    FGLATVNS 8
            FG+AT+N+
Sbjct: 4450 FGVATLNT 4457
>XP_006710283
          Length = 2066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    FGLATVNS 8
            FG+AT+N+
Sbjct: 1416 FGVATLNT 1423
>XP_006710282
          Length = 2621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    FGLATVNS 8
            FG+AT+N+
Sbjct: 1971 FGVATLNT 1978
>NP_001265
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 149 FGLATV 154
>NP_001231775
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 149 FGLATV 154
>NP_001107593
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 149 FGLATV 154
>NP_001107594
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 149 FGLATV 154
>NP_001035351
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 555 FGLATV 560
>NP_001035350
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 538 FGLATV 543
>NP_212133
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>NP_940938
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>NP_001138888
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>XP_005259958
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>XP_005259957
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>XP_005259959
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>XP_005259956
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>XP_005259955
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVN+R
Sbjct: 98  LATVNAR 104
>XP_006718822
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 149 FGLATV 154
>XP_005262843
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 537 FGLATV 542
>XP_005262842
          Length = 782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLATV
Sbjct: 554 FGLATV 559
>NP_203519
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>NP_001219
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 419 GMATVNN 425
>NP_001073593
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 387 GMATVNN 393
>NP_203520
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 387 GMATVNN 393
>NP_001073594
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 461 GMATVNN 467
>NP_001810
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  GLATVNS 8
          GLA VNS
Sbjct: 14 GLAAVNS 20
>NP_001182345
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLAT+
Sbjct: 227 FGLATI 232
>NP_004725
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLAT+
Sbjct: 534 FGLATI 539
>NP_001182344
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLAT+
Sbjct: 227 FGLATI 232
>NP_079489
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVNSR 9
           LATVNS+
Sbjct: 118 LATVNSQ 124
>NP_066022
          Length = 2564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LATVNSR 9
            LATVNS+
Sbjct: 1442 LATVNSQ 1448
>XP_006723369
          Length = 2394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LATVNSR 9
            LATVNS+
Sbjct: 1442 LATVNSQ 1448
>XP_006719956
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLAT+
Sbjct: 534 FGLATI 539
>XP_005266649
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGLATV 6
           FGLAT+
Sbjct: 534 FGLATI 539
>XP_005246951
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 203 GMATVNN 209
>XP_006712854
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 377 GMATVNN 383
>XP_005246949
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 387 GMATVNN 393
>XP_006712853
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_005246948
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_005246947
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_005246945
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_006712852
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_005246946
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_005246944
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_005246943
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 402 GMATVNN 408
>XP_005246942
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLATVNS 8
           G+ATVN+
Sbjct: 446 GMATVNN 452
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.134    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 308,386
Number of extensions: 369
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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