Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005270847                                                           17    4312
NP_001516                                                              17    4312
NP_001120727                                                           16    7355
NP_631915                                                              16    7355
NP_055640                                                              16    7355
XP_006726254                                                           16    7355
XP_006726253                                                           16    7355
XP_006726252                                                           16    7355
XP_006726214                                                           16    7355
XP_006726213                                                           16    7355
XP_006726212                                                           16    7355
XP_006726371                                                           16    7355
XP_006726370                                                           16    7355
XP_006726116                                                           16    7355
XP_006726115                                                           16    7355
XP_006726114                                                           16    7355
XP_006726017                                                           16    7355
XP_006726016                                                           16    7355
XP_006726015                                                           16    7355
XP_006725929                                                           16    7355
XP_006725928                                                           16    7355
XP_006725927                                                           16    7355
XP_006725828                                                           16    7355
XP_006725827                                                           16    7355
XP_006725826                                                           16    7355
XP_006725701                                                           16    7355
XP_006725700                                                           16    7355
XP_006725699                                                           16    7355
XP_006726334                                                           16    7355
XP_006726333                                                           16    7355
XP_006726332                                                           16    7355
XP_006723139                                                           16    7355
XP_006723138                                                           16    7355
XP_006723137                                                           16    7355
NP_059110                                                              15    9605
NP_002411                                                              15    9605
NP_001238953                                                           15    9605
NP_001238949                                                           15    9605
NP_079247                                                              15    9605
NP_001007472                                                           15    9605
NP_066003                                                              15    9605
NP_996830                                                              15    9605
NP_996829                                                              15    9605
NP_996828                                                              15    9605
NP_996827                                                              15    9605
XP_005252275                                                           15    9605
XP_006711533                                                           15    9605
XP_005245422                                                           15    9605
NP_065821                                                              15    9605
>XP_005270847
          Length = 283

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGILRQAS 8
           FG+ RQAS
Sbjct: 238 FGMFRQAS 245
>NP_001516
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FGILRQAS 8
           FG+ RQAS
Sbjct: 324 FGMFRQAS 331
>NP_001120727
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>NP_631915
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 952 FGVLRQ 957
>NP_055640
          Length = 2271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1789 FGVLRQ 1794
>XP_006726254
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726253
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726252
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006726214
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726213
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726212
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006726371
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726370
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726116
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726115
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726114
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006726017
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726016
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726015
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006725929
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006725928
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006725927
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006725828
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006725827
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006725826
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006725701
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006725700
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006725699
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006726334
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726333
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006726332
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>XP_006723139
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006723138
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FGILRQ 6
           FG+LRQ
Sbjct: 980 FGVLRQ 985
>XP_006723137
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FGILRQ 6
            FG+LRQ
Sbjct: 1007 FGVLRQ 1012
>NP_059110
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  FGILRQ 6
          FG+LRQ
Sbjct: 5  FGLLRQ 10
>NP_002411
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FGILRQA 7
           FG+ RQA
Sbjct: 980 FGVARQA 986
>NP_001238953
          Length = 1625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FGILRQA 7
            FG+ RQA
Sbjct: 1002 FGVARQA 1008
>NP_001238949
          Length = 1642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FGILRQA 7
            FG+ RQA
Sbjct: 1019 FGVARQA 1025
>NP_079247
          Length = 1566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FGILRQA 7
           FG+ RQA
Sbjct: 881 FGVARQA 887
>NP_001007472
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FGILRQA 7
            FG+ RQA
Sbjct: 1022 FGVARQA 1028
>NP_066003
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FGILRQA 7
           FG+ RQA
Sbjct: 869 FGVARQA 875
>NP_996830
          Length = 1569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FGILRQA 7
           FG+ RQA
Sbjct: 884 FGVARQA 890
>NP_996829
          Length = 1579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FGILRQA 7
           FG+ RQA
Sbjct: 894 FGVARQA 900
>NP_996828
          Length = 1556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FGILRQA 7
           FG+ RQA
Sbjct: 871 FGVARQA 877
>NP_996827
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FGILRQA 7
           FG+ RQA
Sbjct: 859 FGVARQA 865
>XP_005252275
          Length = 1734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FGILRQA 7
            FG+ RQA
Sbjct: 1049 FGVARQA 1055
>XP_006711533
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGILRQAS 8
           +GILR+ S
Sbjct: 319 YGILREGS 326
>XP_005245422
          Length = 1203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGILRQAS 8
           +GILR+ S
Sbjct: 319 YGILREGS 326
>NP_065821
          Length = 1203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FGILRQAS 8
           +GILR+ S
Sbjct: 319 YGILREGS 326
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.147    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 348,853
Number of extensions: 326
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package