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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004000                                                              18    1935
NP_004001                                                              18    1935
NP_003997                                                              18    1935
NP_000100                                                              18    1935
XP_006724538                                                           18    1935
XP_006724537                                                           18    1935
XP_006724536                                                           18    1935
XP_006724535                                                           18    1935
XP_006724534                                                           18    1935
XP_006724533                                                           18    1935
XP_006724532                                                           18    1935
XP_006724531                                                           18    1935
NP_064627                                                              16    5631
XP_006713328                                                           16    5631
XP_006713327                                                           16    5631
XP_006713326                                                           16    5631
XP_006713325                                                           16    5631
XP_006713324                                                           16    5631
XP_005265385                                                           16    5631
NP_997191                                                              16    7355
NP_001152956                                                           16    7355
XP_006711682                                                           16    7355
XP_006711061                                                           16    7355
XP_006711060                                                           16    7355
XP_005244868                                                           16    7355
XP_003119848                                                           16    7355
NP_954657                                                              15    9605
NP_000215                                                              15    9605
NP_001170991                                                           15    9605
NP_001120973                                                           15    9605
NP_000469                                                              15    9605
XP_005245875                                                           15    9605
XP_006710609                                                           15    9605

>NP_004000
          Length = 3681

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 679 ETVTTVTTR 687



>NP_004001
          Length = 3562

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 560 ETVTTVTTR 568



>NP_003997
          Length = 3685

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 683 ETVTTVTTR 691



>NP_000100
          Length = 3677

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 675 ETVTTVTTR 683



>XP_006724538
          Length = 3575

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 683 ETVTTVTTR 691



>XP_006724537
          Length = 3593

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 683 ETVTTVTTR 691



>XP_006724536
          Length = 3657

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 683 ETVTTVTTR 691



>XP_006724535
          Length = 3660

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 640 ETVTTVTTR 648



>XP_006724534
          Length = 3668

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 683 ETVTTVTTR 691



>XP_006724533
          Length = 3690

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 683 ETVTTVTTR 691



>XP_006724532
          Length = 3695

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 675 ETVTTVTTR 683



>XP_006724531
          Length = 3703

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+T +TTR
Sbjct: 683 ETVTTVTTR 691



>NP_064627
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETLTVITT 8
           ETL +ITT
Sbjct: 654 ETLKIITT 661



>XP_006713328
          Length = 992

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETLTVITT 8
           ETL +ITT
Sbjct: 654 ETLKIITT 661



>XP_006713327
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETLTVITT 8
           ETL +ITT
Sbjct: 289 ETLKIITT 296



>XP_006713326
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETLTVITT 8
           ETL +ITT
Sbjct: 654 ETLKIITT 661



>XP_006713325
          Length = 1195

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETLTVITT 8
           ETL +ITT
Sbjct: 654 ETLKIITT 661



>XP_006713324
          Length = 1285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETLTVITT 8
           ETL +ITT
Sbjct: 654 ETLKIITT 661



>XP_005265385
          Length = 1291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETLTVITT 8
           ETL +ITT
Sbjct: 557 ETLKIITT 564



>NP_997191
          Length = 1888

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+ ++TT+
Sbjct: 503 ETVVIVTTK 511



>NP_001152956
          Length = 1736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+ ++TT+
Sbjct: 503 ETVVIVTTK 511



>XP_006711682
          Length = 1739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           ET+ ++TT+
Sbjct: 354 ETVVIVTTK 362



>XP_006711061
          Length = 1553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ETLTVITTR 9
            ETL +IT R
Sbjct: 1233 ETLDIITKR 1241



>XP_006711060
          Length = 1595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ETLTVITTR 9
            ETL +IT R
Sbjct: 1275 ETLDIITKR 1283



>XP_005244868
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ETLTVITTR 9
            ETL +IT R
Sbjct: 1319 ETLDIITKR 1327



>XP_003119848
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETLTVITTR 9
           ETL +IT R
Sbjct: 195 ETLDIITKR 203



>NP_954657
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           E+ TV+TT+
Sbjct: 277 ESTTVVTTQ 285



>NP_000215
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETLTVITTR 9
           E+ TV+TT+
Sbjct: 277 ESTTVVTTQ 285



>NP_001170991
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETLTVIT 7
           +TLTV+T
Sbjct: 293 DTLTVVT 299



>NP_001120973
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETLTVIT 7
           +TLTV+T
Sbjct: 315 DTLTVVT 321



>NP_000469
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETLTVIT 7
           +TLTV+T
Sbjct: 370 DTLTVVT 376



>XP_005245875
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETLTVIT 7
           +TLTV+T
Sbjct: 370 DTLTVVT 376



>XP_006710609
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETLTVIT 7
           +TLTV+T
Sbjct: 370 DTLTVVT 376



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.124    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 305,327
Number of extensions: 365
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)