Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_060130                                                              17    3301
NP_001269789                                                           17    3301
NP_001269787                                                           17    3301
NP_001269790                                                           17    3301
NP_115668                                                              17    3301
NP_001269785                                                           17    3301
XP_005260019                                                           17    3301
XP_005260018                                                           17    3301
XP_005260017                                                           17    3301
XP_005260016                                                           17    3301
XP_005260015                                                           17    3301
XP_006722844                                                           17    3301
XP_005260014                                                           17    3301
XP_006722843                                                           17    3301
XP_005260013                                                           17    3301
XP_005260011                                                           17    3301
XP_005245341                                                           17    3301
XP_006711459                                                           17    3301
XP_005245340                                                           17    3301
XP_006711458                                                           17    3301
XP_006711457                                                           17    3301
XP_006711456                                                           17    3301
NP_003827                                                              17    4312
NP_055517                                                              16    5631
NP_006039                                                              15    9605
NP_001099032                                                           15    9605
NP_001257881                                                           15    9605
NP_001036167                                                           15    9605
NP_065914                                                              15    9605
NP_001167628                                                           15    9605
NP_001276323                                                           15    9605
NP_001025110                                                           15    9605
NP_001161055                                                           15    9605
NP_001003811                                                           15    9605
NP_005993                                                              15    9605
XP_005246686                                                           15    9605
XP_006712617                                                           15    9605
XP_005246684                                                           15    9605
XP_005246683                                                           15    9605
XP_005263479                                                           15    9605
NP_071745                                                              15    9605
NP_112566                                                              15    9605
NP_001123612                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2182 ETVTEALLE 2190
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2203 ETVTEALLE 2211
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2213 ETVTEALLE 2221
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2213 ETVTEALLE 2221
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2182 ETVTEALLE 2190
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2192 ETVTEALLE 2200
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2213 ETVTEALLE 2221
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2200 ETVTEALLE 2208
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2203 ETVTEALLE 2211
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            ET TEALLE
Sbjct: 2213 ETVTEALLE 2221
>NP_060130
          Length = 633

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 127 ETSTEALMK 135
>NP_001269789
          Length = 2241

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>NP_001269787
          Length = 2240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>NP_001269790
          Length = 1529

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>NP_115668
          Length = 1529

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>NP_001269785
          Length = 2241

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>XP_005260019
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  ETATEALLE 9
          ET+TEAL++
Sbjct: 36 ETSTEALMK 44
>XP_005260018
          Length = 634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 127 ETSTEALMK 135
>XP_005260017
          Length = 634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 127 ETSTEALMK 135
>XP_005260016
          Length = 634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 127 ETSTEALMK 135
>XP_005260015
          Length = 634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 127 ETSTEALMK 135
>XP_006722844
          Length = 640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 158 ETSTEALMK 166
>XP_005260014
          Length = 653

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 146 ETSTEALMK 154
>XP_006722843
          Length = 653

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 146 ETSTEALMK 154
>XP_005260013
          Length = 653

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 146 ETSTEALMK 154
>XP_005260011
          Length = 665

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ETATEALLE 9
           ET+TEAL++
Sbjct: 158 ETSTEALMK 166
>XP_005245341
          Length = 2068

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 211 ETAEESLLE 219
>XP_006711459
          Length = 2240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>XP_005245340
          Length = 2211

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>XP_006711458
          Length = 2240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>XP_006711457
          Length = 2240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>XP_006711456
          Length = 2240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETA E+LLE
Sbjct: 383 ETAEESLLE 391
>NP_003827
          Length = 383

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2 TATEALL 8
         TATEALL
Sbjct: 2 TATEALL 8
>NP_055517
          Length = 694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ETATE+ L+
Sbjct: 571 ETATESALQ 579
>NP_006039
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            +T TE++LE
Sbjct: 1144 QTLTESMLE 1152
>NP_001099032
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            +T TE++LE
Sbjct: 1273 QTLTESMLE 1281
>NP_001257881
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETATEALLE 9
           ET+ E LLE
Sbjct: 159 ETSDETLLE 167
>NP_001036167
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETATEALL 8
           ETAT ALL
Sbjct: 238 ETATFALL 245
>NP_065914
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ETATEA 6
            ETATEA
Sbjct: 1078 ETATEA 1083
>NP_001167628
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ETATEA 6
            ETATEA
Sbjct: 1016 ETATEA 1021
>NP_001276323
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ETATEA 6
            ETATEA
Sbjct: 1066 ETATEA 1071
>NP_001025110
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ETATEA 6
            ETATEA
Sbjct: 1066 ETATEA 1071
>NP_001161055
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ETATEA 6
            ETATEA
Sbjct: 1066 ETATEA 1071
>NP_001003811
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETATEALLE 9
           ET+ E LLE
Sbjct: 315 ETSNEELLE 323
>NP_005993
          Length = 230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETATEALLE 9
           ET+ E LLE
Sbjct: 195 ETSDETLLE 203
>XP_005246686
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETATEALL 8
           ETAT ALL
Sbjct: 235 ETATFALL 242
>XP_006712617
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETATEALL 8
           ETAT ALL
Sbjct: 238 ETATFALL 245
>XP_005246684
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETATEALL 8
           ETAT ALL
Sbjct: 241 ETATFALL 248
>XP_005246683
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETATEALL 8
           ETAT ALL
Sbjct: 273 ETATFALL 280
>XP_005263479
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ETATEALLE 9
            +T TE++LE
Sbjct: 1324 QTLTESMLE 1332
>NP_071745
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ET++ ALLE
Sbjct: 690 ETSSPALLE 698
>NP_112566
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETATEALLE 9
           ET+ E LLE
Sbjct: 300 ETSNEELLE 308
>NP_001123612
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETATEALLE 9
           ET++ ALLE
Sbjct: 690 ETSSPALLE 698
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290    0.108    0.239 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 303,191
Number of extensions: 466
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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