Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245202                                                           18    1935
NP_001245200                                                           18    1935
NP_001161091                                                           18    1935
NP_000240                                                              18    1935
NP_001161090                                                           18    1935
NP_001161089                                                           18    1935
NP_001245203                                                           18    1935
XP_005265221                                                           18    1935
XP_005265220                                                           18    1935
NP_001013649                                                           17    4312
XP_006724707                                                           17    4312
NP_065753                                                              16    7355
XP_006716871                                                           16    7355
XP_006710602                                                           16    7355
XP_006710601                                                           16    7355
XP_006710598                                                           16    7355
XP_006710597                                                           16    7355
XP_006710596                                                           16    7355
XP_006710595                                                           16    7355
XP_006710594                                                           16    7355
XP_006710593                                                           16    7355
XP_006710592                                                           16    7355
XP_006710591                                                           16    7355
XP_006710590                                                           16    7355
XP_006710589                                                           16    7355
XP_006710588                                                           16    7355
XP_006710587                                                           16    7355
XP_006710586                                                           16    7355
XP_006710585                                                           16    7355
XP_005270755                                                           16    7355
XP_006710584                                                           16    7355
XP_005270754                                                           16    7355
XP_005270753                                                           16    7355
XP_006710583                                                           16    7355
XP_005270752                                                           16    7355
XP_006710582                                                           16    7355
XP_005270751                                                           16    7355
NP_003740                                                              15    9605
NP_001243888                                                           15    9605
NP_001277                                                              15    9605
>NP_001245202
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESISLRKAI 9
          ES SLRKAI
Sbjct: 27 ESTSLRKAI 35
>NP_001245200
          Length = 687

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESISLRKAI 9
           ES SLRKAI
Sbjct: 268 ESTSLRKAI 276
>NP_001161091
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESISLRKAI 9
          ES SLRKAI
Sbjct: 27 ESTSLRKAI 35
>NP_000240
          Length = 756

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESISLRKAI 9
           ES SLRKAI
Sbjct: 268 ESTSLRKAI 276
>NP_001161090
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESISLRKAI 9
          ES SLRKAI
Sbjct: 27 ESTSLRKAI 35
>NP_001161089
          Length = 658

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESISLRKAI 9
           ES SLRKAI
Sbjct: 170 ESTSLRKAI 178
>NP_001245203
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESISLRKAI 9
          ES SLRKAI
Sbjct: 27 ESTSLRKAI 35
>XP_005265221
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESISLRKAI 9
          ES SLRKAI
Sbjct: 27 ESTSLRKAI 35
>XP_005265220
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESISLRKAI 9
          ES SLRKAI
Sbjct: 27 ESTSLRKAI 35
>NP_001013649
          Length = 1225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   ESISLRKA 8
           +SISLRKA
Sbjct: 557 KSISLRKA 564
>XP_006724707
          Length = 1337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   ESISLRKA 8
           +SISLRKA
Sbjct: 669 KSISLRKA 676
>NP_065753
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SISLRKA 8
          S+SLRKA
Sbjct: 79 SVSLRKA 85
>XP_006716871
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SISLRKA 8
          S+SLRKA
Sbjct: 79 SVSLRKA 85
>XP_006710602
          Length = 7391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2558 ENISLPKAI 2566
>XP_006710601
          Length = 4720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_006710598
          Length = 7553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2548 ENISLPKAI 2556
>XP_006710597
          Length = 7451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2558 ENISLPKAI 2566
>XP_006710596
          Length = 7512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2507 ENISLPKAI 2515
>XP_006710595
          Length = 7526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2521 ENISLPKAI 2529
>XP_006710594
          Length = 7528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2523 ENISLPKAI 2531
>XP_006710593
          Length = 7539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2534 ENISLPKAI 2542
>XP_006710592
          Length = 7544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2539 ENISLPKAI 2547
>XP_006710591
          Length = 7558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2553 ENISLPKAI 2561
>XP_006710590
          Length = 7563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2558 ENISLPKAI 2566
>XP_006710589
          Length = 7595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2590 ENISLPKAI 2598
>XP_006710588
          Length = 7614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_006710587
          Length = 7645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_006710586
          Length = 7645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_006710585
          Length = 7657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_005270755
          Length = 7663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_006710584
          Length = 7686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_005270754
          Length = 7694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_005270753
          Length = 7700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_006710583
          Length = 7702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_005270752
          Length = 7717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_006710582
          Length = 7720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>XP_005270751
          Length = 7723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESISLRKAI 9
            E+ISL KAI
Sbjct: 2718 ENISLPKAI 2726
>NP_003740
          Length = 1338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ESISLRKA 8
            E++SLRK+
Sbjct: 1178 ENVSLRKS 1185
>NP_001243888
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ESISLRK 7
           +SISLRK
Sbjct: 196 QSISLRK 202
>NP_001277
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ESISLRK 7
           +SISLRK
Sbjct: 218 QSISLRK 224
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.127    0.279 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 321,178
Number of extensions: 341
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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