Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              19     665
NP_079410                                                              17    3301
NP_000683                                                              17    3301
XP_005256233                                                           17    3301
XP_005256232                                                           17    3301
XP_005256231                                                           17    3301
XP_005256229                                                           17    3301
XP_005256228                                                           17    3301
XP_005256227                                                           17    3301
XP_006721346                                                           17    3301
XP_005256226                                                           17    3301
XP_006721345                                                           17    3301
XP_006721344                                                           17    3301
XP_006721343                                                           17    3301
XP_005256225                                                           17    3301
XP_006710237                                                           17    3301
NP_003602                                                              17    4312
XP_005274666                                                           17    4312
XP_005274664                                                           17    4312
XP_005274663                                                           17    4312
XP_005274662                                                           17    4312
XP_005274661                                                           17    4312
XP_005274660                                                           17    4312
XP_005274659                                                           17    4312
XP_005274658                                                           17    4312
XP_005274657                                                           17    4312
XP_005274656                                                           17    4312
NP_060050                                                              16    5631
NP_079464                                                              16    5631
NP_001139107                                                           16    5631
XP_005269983                                                           16    5631
XP_005269982                                                           16    5631
XP_006717970                                                           16    5631
NP_115936                                                              16    7355
NP_001263309                                                           16    7355
NP_057733                                                              16    7355
NP_065928                                                              16    7355
NP_001147135                                                           16    7355
NP_001147107                                                           16    7355
XP_005256527                                                           16    7355
XP_005263227                                                           16    7355
NP_001147057                                                           16    7355
NP_001146918                                                           16    7355
NP_001146956                                                           16    7355
NP_006735                                                              15    9605
NP_079452                                                              15    9605
XP_005261469                                                           15    9605
XP_006723617                                                           15    9605
XP_005260737                                                           15    9605
XP_005260736                                                           15    9605
XP_006723616                                                           15    9605
XP_006723615                                                           15    9605
XP_005260735                                                           15    9605
XP_005270080                                                           15    9605
NP_055107                                                              15    9605
>NP_115927
          Length = 1321

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           ER RLLNRV
Sbjct: 697 ERARLLNRV 705
>NP_079410
          Length = 2881

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2543 ERVQLINR 2550
>NP_000683
          Length = 517

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           ER RLLNR+
Sbjct: 100 ERGRLLNRL 108
>XP_005256233
          Length = 2391

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2053 ERVQLINR 2060
>XP_005256232
          Length = 2424

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2086 ERVQLINR 2093
>XP_005256231
          Length = 2573

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_005256229
          Length = 2881

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2543 ERVQLINR 2550
>XP_005256228
          Length = 2882

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2544 ERVQLINR 2551
>XP_005256227
          Length = 2897

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2559 ERVQLINR 2566
>XP_006721346
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_005256226
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006721345
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006721344
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006721343
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_005256225
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ERVRLLNR 8
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006710237
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ERVRLLNR 8
          ERVRLL R
Sbjct: 51 ERVRLLER 58
>NP_003602
          Length = 1012

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 464 ENLRLLNRL 472
>XP_005274666
          Length = 550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ERVRLLNRV 9
          E +RLLNR+
Sbjct: 39 ENLRLLNRL 47
>XP_005274664
          Length = 872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 324 ENLRLLNRL 332
>XP_005274663
          Length = 964

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 416 ENLRLLNRL 424
>XP_005274662
          Length = 971

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 424 ENLRLLNRL 432
>XP_005274661
          Length = 972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 424 ENLRLLNRL 432
>XP_005274660
          Length = 979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 431 ENLRLLNRL 439
>XP_005274659
          Length = 982

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 471 ENLRLLNRL 479
>XP_005274658
          Length = 1011

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 464 ENLRLLNRL 472
>XP_005274657
          Length = 1018

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 471 ENLRLLNRL 479
>XP_005274656
          Length = 1019

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E +RLLNR+
Sbjct: 471 ENLRLLNRL 479
>NP_060050
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           + VRLLNR
Sbjct: 298 DEVRLLNR 305
>NP_079464
          Length = 580

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           ER+R LN+V
Sbjct: 352 ERLRKLNKV 360
>NP_001139107
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           ER+R LN+V
Sbjct: 352 ERLRKLNKV 360
>XP_005269983
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           + VRLLNR
Sbjct: 298 DEVRLLNR 305
>XP_005269982
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           + VRLLNR
Sbjct: 324 DEVRLLNR 331
>XP_006717970
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           + VRLLNR
Sbjct: 324 DEVRLLNR 331
>NP_115936
          Length = 122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ERVRLLNRV 9
          E+ RL+N+V
Sbjct: 59 EKTRLINQV 67
>NP_001263309
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           ER+ +LNR
Sbjct: 517 ERITMLNR 524
>NP_057733
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           ER+ +LNR
Sbjct: 517 ERITMLNR 524
>NP_065928
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERVRLLNR 8
           ER+RLL++
Sbjct: 699 ERIRLLDK 706
>NP_001147135
          Length = 158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E+ RL+N+V
Sbjct: 95  EKTRLINQV 103
>NP_001147107
          Length = 121

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ERVRLLNRV 9
          E+ RL+N+V
Sbjct: 58 EKTRLINQV 66
>XP_005256527
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERVRLLNR 8
           ER+RLL++
Sbjct: 699 ERIRLLDK 706
>XP_005263227
          Length = 181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E+ RL+N+V
Sbjct: 118 EKTRLINQV 126
>NP_001147057
          Length = 122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ERVRLLNRV 9
          E+ RL+N+V
Sbjct: 59 EKTRLINQV 67
>NP_001146918
          Length = 122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ERVRLLNRV 9
          E+ RL+N+V
Sbjct: 59 EKTRLINQV 67
>NP_001146956
          Length = 159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E+ RL+N+V
Sbjct: 96  EKTRLINQV 104
>NP_006735
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RVRLLN 7
          RVRLLN
Sbjct: 78 RVRLLN 83
>NP_079452
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ERVRLLNRV 9
            E+VR LN++
Sbjct: 1363 EKVRALNKL 1371
>XP_005261469
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           E VR++NR
Sbjct: 137 ETVRIINR 144
>XP_006723617
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERVRLLNRV 9
           E+VR LN++
Sbjct: 743 EKVRALNKL 751
>XP_005260737
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ERVRLLNRV 9
            E+VR LN++
Sbjct: 996  EKVRALNKL 1004
>XP_005260736
          Length = 1033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ERVRLLNRV 9
            E+VR LN++
Sbjct: 1014 EKVRALNKL 1022
>XP_006723616
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ERVRLLNRV 9
            E+VR LN++
Sbjct: 1204 EKVRALNKL 1212
>XP_006723615
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ERVRLLNRV 9
            E+VR LN++
Sbjct: 1363 EKVRALNKL 1371
>XP_005260735
          Length = 1398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ERVRLLNRV 9
            E+VR LN++
Sbjct: 1379 EKVRALNKL 1387
>XP_005270080
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RVRLLN 7
           RVRLLN
Sbjct: 142 RVRLLN 147
>NP_055107
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERVRLLNR 8
           E VR++NR
Sbjct: 155 ETVRIINR 162
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.149    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 363,537
Number of extensions: 631
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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