Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_871626                                                              17    4312
NP_002709                                                              17    4312
NP_001177376                                                           17    4312
XP_005274106                                                           17    4312
XP_005274105                                                           17    4312
XP_006713749                                                           17    4312
NP_056969                                                              17    4312
NP_689854                                                              16    7355
XP_006719336                                                           16    7355
XP_006719335                                                           16    7355
NP_001029031                                                           15    9605
NP_001257377                                                           15    9605
NP_000009                                                              15    9605
NP_001238892                                                           15    9605
NP_003172                                                              15    9605
NP_001257413                                                           15    9605
NP_001165375                                                           15    9605
NP_055518                                                              15    9605
NP_056093                                                              15    9605
NP_037371                                                              15    9605
NP_001238891                                                           15    9605
NP_001257376                                                           15    9605
NP_056410                                                              15    9605
NP_004904                                                              15    9605
XP_006725715                                                           15    9605
XP_006725714                                                           15    9605
XP_006725713                                                           15    9605
XP_006725712                                                           15    9605
XP_006725479                                                           15    9605
XP_006725478                                                           15    9605
XP_006725477                                                           15    9605
XP_006725476                                                           15    9605
XP_006725061                                                           15    9605
XP_005274834                                                           15    9605
XP_006724926                                                           15    9605
XP_005274833                                                           15    9605
XP_005274485                                                           15    9605
XP_006724505                                                           15    9605
XP_005274484                                                           15    9605
XP_006721413                                                           15    9605
XP_005256386                                                           15    9605
XP_005266932                                                           15    9605
XP_006715469                                                           15    9605
XP_005266931                                                           15    9605
XP_005276812                                                           15    9605
XP_006713491                                                           15    9605
XP_005276811                                                           15    9605
XP_006713490                                                           15    9605
XP_005276810                                                           15    9605
XP_005276809                                                           15    9605
XP_006713489                                                           15    9605
XP_005276808                                                           15    9605
>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ERIANGAIT 9
            ERIA+GAIT
Sbjct: 1020 ERIASGAIT 1028
>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ERIANGAIT 9
            ERIA+GAIT
Sbjct: 1039 ERIASGAIT 1047
>NP_871626
          Length = 529

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           ERI +GA+T
Sbjct: 316 ERIFSGAVT 324
>NP_002709
          Length = 1150

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           ERI +GA+T
Sbjct: 937 ERIFSGAVT 945
>NP_001177376
          Length = 414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           ERI +GA+T
Sbjct: 201 ERIFSGAVT 209
>XP_005274106
          Length = 1685

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           ER+A+G IT
Sbjct: 670 ERLASGEIT 678
>XP_005274105
          Length = 1686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           ER+A+G IT
Sbjct: 670 ERLASGEIT 678
>XP_006713749
          Length = 1150

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           ERI +GA+T
Sbjct: 937 ERIFSGAVT 945
>NP_056969
          Length = 1555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           ER+A+G IT
Sbjct: 670 ERLASGEIT 678
>NP_689854
          Length = 1835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ERIANGAI 8
            ERI+NG +
Sbjct: 1413 ERISNGPV 1420
>XP_006719336
          Length = 1779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ERIANGAI 8
            ERI+NG +
Sbjct: 1357 ERISNGPV 1364
>XP_006719335
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ERIANGAI 8
            ERI+NG +
Sbjct: 1413 ERISNGPV 1420
>NP_001029031
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERIANGAI 8
           +R+A+GAI
Sbjct: 544 QRLADGAI 551
>NP_001257377
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERIANGAI 8
           +R+A+GAI
Sbjct: 490 QRLADGAI 497
>NP_000009
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERIANGAI 8
           +R+A+GAI
Sbjct: 566 QRLADGAI 573
>NP_001238892
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ANGAIT 9
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_003172
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IANGAIT 9
           ++NGA+T
Sbjct: 353 VSNGAVT 359
>NP_001257413
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IANGAIT 9
           ++NGA+T
Sbjct: 295 VSNGAVT 301
>NP_001165375
          Length = 1506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 903 RIANGIAT 910
>NP_055518
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
>NP_056093
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ERIANG 6
           ER+ANG
Sbjct: 994 ERLANG 999
>NP_037371
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 353 DRIFSGAVT 361
>NP_001238891
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ANGAIT 9
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_001257376
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERIANGAI 8
           +R+A+GAI
Sbjct: 589 QRLADGAI 596
>NP_056410
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ANGAIT 9
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_004904
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  RIANGAI 8
          ++ANGAI
Sbjct: 18 KLANGAI 24
>XP_006725715
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_006725714
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_006725713
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 287 DRIFSGAVT 295
>XP_006725712
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 353 DRIFSGAVT 361
>XP_006725479
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_006725478
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_006725477
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 287 DRIFSGAVT 295
>XP_006725476
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 353 DRIFSGAVT 361
>XP_006725061
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ANGAIT 9
           ANGA+T
Sbjct: 129 ANGAVT 134
>XP_005274834
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_006724926
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_005274833
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 287 DRIFSGAVT 295
>XP_005274485
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_006724505
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 192 DRIFSGAVT 200
>XP_005274484
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ERIANGAIT 9
           +RI +GA+T
Sbjct: 287 DRIFSGAVT 295
>XP_006721413
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  RIANGAI 8
          ++ANGAI
Sbjct: 18 KLANGAI 24
>XP_005256386
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  RIANGAI 8
          ++ANGAI
Sbjct: 18 KLANGAI 24
>XP_005266932
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ERIANG 6
           ER+ANG
Sbjct: 755 ERLANG 760
>XP_006715469
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ERIANG 6
           ER+ANG
Sbjct: 982 ERLANG 987
>XP_005266931
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    ERIANG 6
            ER+ANG
Sbjct: 1030 ERLANG 1035
>XP_005276812
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
>XP_006713491
          Length = 1425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 822 RIANGIAT 829
>XP_005276811
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
>XP_006713490
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
>XP_005276810
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
>XP_005276809
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
>XP_006713489
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
>XP_005276808
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIANGAIT 9
           RIANG  T
Sbjct: 904 RIANGIAT 911
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.130    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 469,546
Number of extensions: 527
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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