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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1135
NP_001093320                                                           17    4312
NP_001093260                                                           17    4312
NP_001094101                                                           17    4312
NP_001161337                                                           17    4312
NP_060085                                                              17    4312
NP_001003845                                                           17    4312
NP_001008395                                                           17    4312
XP_005269987                                                           17    4312
XP_005269986                                                           17    4312
XP_005269985                                                           17    4312
XP_005246599                                                           17    4312
NP_689704                                                              16    5631
NP_002262                                                              16    5631
XP_005254110                                                           16    5631
XP_005254109                                                           16    5631
XP_005254106                                                           16    5631
XP_006711241                                                           16    5631
NP_001138820                                                           16    7355
NP_079049                                                              16    7355
NP_000377                                                              16    7355
XP_006721155                                                           16    7355
NP_001019832                                                           15    9605
NP_001278309                                                           15    9605
NP_056161                                                              15    9605
NP_075390                                                              15    9605
NP_079335                                                              15    9605
XP_006726395                                                           15    9605
XP_006725017                                                           15    9605
XP_006720156                                                           15    9605
XP_006715631                                                           15    9605
XP_006711144                                                           15    9605

>NP_004251
          Length = 1208

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ERIAALLQT 9
           ERIAALL+T
Sbjct: 714 ERIAALLRT 722



>NP_001093320
          Length = 479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E++AA LQT
Sbjct: 345 EKVAATLQT 353



>NP_001093260
          Length = 479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E++AA LQT
Sbjct: 345 EKVAATLQT 353



>NP_001094101
          Length = 481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E++AA LQT
Sbjct: 347 EKVAATLQT 355



>NP_001161337
          Length = 384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ERIAALLQT 9
           ERI  LLQT
Sbjct: 268 ERILGLLQT 276



>NP_060085
          Length = 385

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ERIAALLQT 9
           ERI  LLQT
Sbjct: 268 ERILGLLQT 276



>NP_001003845
          Length = 398

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   RIAALLQT 9
           +IAALLQT
Sbjct: 253 QIAALLQT 260



>NP_001008395
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ERIAALLQT 9
           ERI  LLQT
Sbjct: 222 ERILGLLQT 230



>XP_005269987
          Length = 226

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ERIAALLQT 9
           ERI  LLQT
Sbjct: 109 ERILGLLQT 117



>XP_005269986
          Length = 226

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ERIAALLQT 9
           ERI  LLQT
Sbjct: 109 ERILGLLQT 117



>XP_005269985
          Length = 316

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ERIAALLQT 9
           ERI  LLQT
Sbjct: 268 ERILGLLQT 276



>XP_005246599
          Length = 442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   RIAALLQT 9
           +IAALLQT
Sbjct: 297 QIAALLQT 304



>NP_689704
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ERIAALLQT 9
           +RI+ALLQ+
Sbjct: 199 QRISALLQS 207



>NP_002262
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IAALLQT 9
           IAALLQT
Sbjct: 461 IAALLQT 467



>XP_005254110
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IAALLQT 9
           IAALLQT
Sbjct: 461 IAALLQT 467



>XP_005254109
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IAALLQT 9
           IAALLQT
Sbjct: 461 IAALLQT 467



>XP_005254106
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IAALLQT 9
           IAALLQT
Sbjct: 461 IAALLQT 467



>XP_006711241
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ERIAALLQT 9
           +RI+ALLQ+
Sbjct: 199 QRISALLQS 207



>NP_001138820
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RIAALLQT 9
           ++AA+LQT
Sbjct: 178 KVAAILQT 185



>NP_079049
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RIAALLQT 9
           ++AA+LQT
Sbjct: 140 KVAAILQT 147



>NP_000377
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ERIAALLQ 8
          E++AAL+Q
Sbjct: 9  EKVAALIQ 16



>XP_006721155
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RIAALLQT 9
           ++AA+LQT
Sbjct: 151 KVAAILQT 158



>NP_001019832
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E+IAA L+T
Sbjct: 345 EKIAASLET 353



>NP_001278309
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E+IAA L+T
Sbjct: 345 EKIAASLET 353



>NP_056161
          Length = 2539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ERIAALL 7
            ER+AALL
Sbjct: 1208 ERLAALL 1214



>NP_075390
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E+IAA L+T
Sbjct: 345 EKIAASLET 353



>NP_079335
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ERIAALLQ 8
           E+IAALL+
Sbjct: 328 EKIAALLR 335



>XP_006726395
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ERIAALLQT 9
          E++AA L+T
Sbjct: 36 EKVAATLET 44



>XP_006725017
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E+IAA L+T
Sbjct: 100 EKIAASLET 108



>XP_006720156
          Length = 2497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ERIAALL 7
            ER+AALL
Sbjct: 1208 ERLAALL 1214



>XP_006715631
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ERIAALLQ 8
           E+IAALL+
Sbjct: 328 EKIAALLR 335



>XP_006711144
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERIAALLQT 9
           E+IAA L+T
Sbjct: 100 EKIAASLET 108



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.131    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 305,212
Number of extensions: 639
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)