Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     869
XP_005265800                                                           19     869
XP_006714103                                                           19     869
XP_006714102                                                           19     869
XP_006726603                                                           17    2528
XP_006725215                                                           17    2528
XP_006719239                                                           17    2528
XP_006719237                                                           17    2528
NP_904325                                                              16    5631
NP_001167597                                                           16    5631
NP_001167596                                                           16    5631
NP_001167600                                                           16    5631
NP_000608                                                              16    5631
NP_001167599                                                           16    5631
NP_001167598                                                           16    5631
XP_005268968                                                           16    5631
NP_056171                                                              16    7355
NP_874365                                                              16    7355
NP_940820                                                              16    7355
NP_001028776                                                           16    7355
NP_001028777                                                           16    7355
NP_055266                                                              16    7355
XP_006715751                                                           16    7355
XP_005249757                                                           16    7355
XP_006715750                                                           16    7355
NP_006603                                                              15    9605
XP_005256481                                                           15    9605
>NP_006197
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    EQRLSADS 8
            EQRLSADS
Sbjct: 1009 EQRLSADS 1016
>XP_005265800
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    EQRLSADS 8
            EQRLSADS
Sbjct: 1009 EQRLSADS 1016
>XP_006714103
          Length = 1111

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    EQRLSADS 8
            EQRLSADS
Sbjct: 1031 EQRLSADS 1038
>XP_006714102
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    EQRLSADS 8
            EQRLSADS
Sbjct: 1034 EQRLSADS 1041
>XP_006726603
          Length = 1264

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EQRLSADSV 9
           EQ+LSA+SV
Sbjct: 413 EQQLSAESV 421
>XP_006725215
          Length = 1264

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EQRLSADSV 9
           EQ+LSA+SV
Sbjct: 413 EQQLSAESV 421
>XP_006719239
          Length = 1066

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EQRLSADSV 9
           EQ+LSA+SV
Sbjct: 628 EQQLSAESV 636
>XP_006719237
          Length = 1263

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EQRLSADSV 9
           EQ+LSA+SV
Sbjct: 413 EQQLSAESV 421
>NP_904325
          Length = 1153

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EQRLSADS 8
           +QRL ADS
Sbjct: 656 QQRLDADS 663
>NP_001167597
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQRLSADSV 9
          EQ++S DSV
Sbjct: 6  EQKMSDDSV 14
>NP_001167596
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQRLSADSV 9
          EQ++S DSV
Sbjct: 35 EQKMSDDSV 43
>NP_001167600
          Length = 561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQRLSADSV 9
          EQ++S DSV
Sbjct: 6  EQKMSDDSV 14
>NP_000608
          Length = 561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQRLSADSV 9
          EQ++S DSV
Sbjct: 6  EQKMSDDSV 14
>NP_001167599
          Length = 561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQRLSADSV 9
          EQ++S DSV
Sbjct: 6  EQKMSDDSV 14
>NP_001167598
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQRLSADSV 9
          EQ++S DSV
Sbjct: 6  EQKMSDDSV 14
>XP_005268968
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQRLSADSV 9
          EQ++S DSV
Sbjct: 35 EQKMSDDSV 43
>NP_056171
          Length = 1630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQRLSADS 8
           E+RLSA+S
Sbjct: 511 EKRLSAES 518
>NP_874365
          Length = 1655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQRLSADS 8
           E+RLSA+S
Sbjct: 511 EKRLSAES 518
>NP_940820
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QRLSADSV 9
           Q+LSAD V
Sbjct: 742 QKLSADQV 749
>NP_001028776
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QRLSADSV 9
           Q+LSAD V
Sbjct: 707 QKLSADQV 714
>NP_001028777
          Length = 882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QRLSADSV 9
           Q+LSAD V
Sbjct: 737 QKLSADQV 744
>NP_055266
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QRLSADSV 9
           Q+LSAD V
Sbjct: 702 QKLSADQV 709
>XP_006715751
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QRLSADSV 9
           Q+LSAD V
Sbjct: 651 QKLSADQV 658
>XP_005249757
          Length = 886

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QRLSADSV 9
           Q+LSAD V
Sbjct: 742 QKLSADQV 749
>XP_006715750
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QRLSADSV 9
           Q+LSAD V
Sbjct: 742 QKLSADQV 749
>NP_006603
          Length = 1103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EQRLSADS 8
           +QRL ADS
Sbjct: 667 QQRLYADS 674
>XP_005256481
          Length = 1103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EQRLSADS 8
           +QRL ADS
Sbjct: 667 QQRLYADS 674
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.113    0.257 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,430
Number of extensions: 575
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package