Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     869
NP_005913                                                              19     869
XP_005267046                                                           19     869
XP_005267045                                                           19     869
NP_001123308                                                           16    5631
NP_001123306                                                           16    5631
NP_001123312                                                           16    5631
NP_001123307                                                           16    5631
NP_001123316                                                           16    5631
NP_001123304                                                           16    5631
NP_001123305                                                           16    5631
NP_001123309                                                           16    5631
NP_001123299                                                           16    5631
NP_001123313                                                           16    5631
NP_000710                                                              16    5631
NP_001123314                                                           16    5631
NP_001123311                                                           16    5631
NP_001123310                                                           16    5631
NP_001123318                                                           16    5631
NP_001123301                                                           16    5631
NP_001123303                                                           16    5631
NP_001123315                                                           16    5631
NP_001123302                                                           16    5631
NP_001161095                                                           16    5631
NP_955630                                                              16    5631
NP_001161096                                                           16    5631
NP_001161097                                                           16    5631
XP_006719080                                                           16    5631
XP_006719079                                                           16    5631
XP_006719078                                                           16    5631
NP_001161210                                                           16    7355
NP_065176                                                              16    7355
XP_006711674                                                           16    7355
XP_006711673                                                           16    7355
XP_006711672                                                           16    7355
XP_006711671                                                           16    7355
XP_006711670                                                           16    7355
XP_005245629                                                           16    7355
NP_001158213                                                           15    9605
NP_001657                                                              15    9605
NP_113584                                                              15    9605
XP_005262029                                                           15    9605
XP_005262028                                                           15    9605
XP_005262026                                                           15    9605
XP_006724637                                                           15    9605
XP_005262025                                                           15    9605
XP_005262024                                                           15    9605
XP_005262023                                                           15    9605
XP_005262022                                                           15    9605
XP_005267567                                                           15    9605
NP_054764                                                              15    9605
>NP_006715
          Length = 1558

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   EPSLLSIK 8
           EPSLLSIK
Sbjct: 642 EPSLLSIK 649
>NP_005913
          Length = 1608

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   EPSLLSIK 8
           EPSLLSIK
Sbjct: 642 EPSLLSIK 649
>XP_005267046
          Length = 1554

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   EPSLLSIK 8
           EPSLLSIK
Sbjct: 642 EPSLLSIK 649
>XP_005267045
          Length = 1604

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   EPSLLSIK 8
           EPSLLSIK
Sbjct: 642 EPSLLSIK 649
>NP_001123308
          Length = 2155

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1867 EPSLLSTEM 1875
>NP_001123306
          Length = 2157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1869 EPSLLSTEM 1877
>NP_001123312
          Length = 2138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1850 EPSLLSTEM 1858
>NP_001123307
          Length = 2157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1869 EPSLLSTEM 1877
>NP_001123316
          Length = 2135

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1847 EPSLLSTEM 1855
>NP_001123304
          Length = 2158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1870 EPSLLSTEM 1878
>NP_001123305
          Length = 2157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1869 EPSLLSTEM 1877
>NP_001123309
          Length = 2146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1858 EPSLLSTEM 1866
>NP_001123299
          Length = 2186

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1898 EPSLLSTEM 1906
>NP_001123313
          Length = 2138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1850 EPSLLSTEM 1858
>NP_000710
          Length = 2138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1850 EPSLLSTEM 1858
>NP_001123314
          Length = 2138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1850 EPSLLSTEM 1858
>NP_001123311
          Length = 2144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1856 EPSLLSTEM 1864
>NP_001123310
          Length = 2146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1858 EPSLLSTEM 1866
>NP_001123318
          Length = 2127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1839 EPSLLSTEM 1847
>NP_001123301
          Length = 2179

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1891 EPSLLSTEM 1899
>NP_001123303
          Length = 2166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1878 EPSLLSTEM 1886
>NP_001123315
          Length = 2138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1850 EPSLLSTEM 1858
>NP_001123302
          Length = 2173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1885 EPSLLSTEM 1893
>NP_001161095
          Length = 2138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1850 EPSLLSTEM 1858
>NP_955630
          Length = 2221

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1933 EPSLLSTEM 1941
>NP_001161096
          Length = 2173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1885 EPSLLSTEM 1893
>NP_001161097
          Length = 2198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1910 EPSLLSTEM 1918
>XP_006719080
          Length = 2168

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1880 EPSLLSTEM 1888
>XP_006719079
          Length = 1459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1171 EPSLLSTEM 1179
>XP_006719078
          Length = 1905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EPSLLSIKL 9
            EPSLLS ++
Sbjct: 1617 EPSLLSTEM 1625
>NP_001161210
          Length = 1483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 308 DPSLLSTK 315
>NP_065176
          Length = 1877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 699 DPSLLSTK 706
>XP_006711674
          Length = 1385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 207 DPSLLSTK 214
>XP_006711673
          Length = 1549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 379 DPSLLSTK 386
>XP_006711672
          Length = 1557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 379 DPSLLSTK 386
>XP_006711671
          Length = 2153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 986 DPSLLSTK 993
>XP_006711670
          Length = 2161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 986 DPSLLSTK 993
>XP_005245629
          Length = 2164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EPSLLSIK 8
           +PSLLS K
Sbjct: 986 DPSLLSTK 993
>NP_001158213
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  EPSLLS 6
          EPSLLS
Sbjct: 93 EPSLLS 98
>NP_001657
          Length = 946

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  EPSLLS 6
          EPSLLS
Sbjct: 93 EPSLLS 98
>NP_113584
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005262029
          Length = 4240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005262028
          Length = 4341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005262026
          Length = 4359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_006724637
          Length = 4365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005262025
          Length = 4373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005262024
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005262023
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005262022
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 569 EPSLLS 574
>XP_005267567
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 655 EPSLLS 660
>NP_054764
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EPSLLS 6
           EPSLLS
Sbjct: 647 EPSLLS 652
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.134    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 596,145
Number of extensions: 818
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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