Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001135920                                                           17    2528
NP_001135921                                                           17    2528
XP_006721159                                                           17    2528
XP_005255675                                                           17    2528
NP_001135923                                                           17    2528
NP_114427                                                              17    2528
NP_001135922                                                           17    2528
XP_006726849                                                           17    3301
XP_006726848                                                           17    3301
XP_006726847                                                           17    3301
XP_006726846                                                           17    3301
XP_006726845                                                           17    3301
XP_006723592                                                           17    3301
XP_006723591                                                           17    3301
XP_006723590                                                           17    3301
XP_006723589                                                           17    3301
XP_006723588                                                           17    3301
XP_006710119                                                           17    3301
XP_006710118                                                           17    3301
XP_006710117                                                           17    3301
XP_006710116                                                           17    3301
XP_006710115                                                           17    3301
NP_001001954                                                           17    4312
NP_071351                                                              16    5631
NP_003483                                                              16    5631
NP_001136336                                                           16    5631
XP_006721417                                                           16    5631
XP_006721416                                                           16    5631
NP_002652                                                              16    7355
NP_005631                                                              16    7355
NP_115612                                                              16    7355
NP_067646                                                              16    7355
NP_065811                                                              16    7355
XP_006722591                                                           16    7355
XP_006712712                                                           16    7355
XP_006712711                                                           16    7355
XP_006712710                                                           16    7355
XP_006712709                                                           16    7355
XP_006711542                                                           16    7355
XP_006711541                                                           16    7355
XP_005245460                                                           16    7355
XP_006711019                                                           16    7355
XP_006711017                                                           16    7355
XP_005246067                                                           16    7355
XP_005246066                                                           16    7355
XP_006711015                                                           16    7355
XP_006711014                                                           16    7355
XP_006711013                                                           16    7355
XP_006711012                                                           16    7355
NP_115971                                                              15    9605
NP_004496                                                              15    9605
XP_005256902                                                           15    9605
NP_001005486                                                           15    9605
>NP_001135920
          Length = 528

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PFLF+SL
Sbjct: 368 PFLFLSL 374
>NP_001135921
          Length = 454

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PFLF+SL
Sbjct: 294 PFLFLSL 300
>XP_006721159
          Length = 521

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PFLF+SL
Sbjct: 361 PFLFLSL 367
>XP_005255675
          Length = 573

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PFLF+SL
Sbjct: 413 PFLFLSL 419
>NP_001135923
          Length = 476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PFLF+SL
Sbjct: 316 PFLFLSL 322
>NP_114427
          Length = 528

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PFLF+SL
Sbjct: 368 PFLFLSL 374
>NP_001135922
          Length = 455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PFLF+SL
Sbjct: 295 PFLFLSL 301
>XP_006726849
          Length = 138

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726848
          Length = 139

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726847
          Length = 141

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726846
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726845
          Length = 150

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723592
          Length = 138

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723591
          Length = 139

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723590
          Length = 141

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723589
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723588
          Length = 150

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710119
          Length = 138

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710118
          Length = 139

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710117
          Length = 141

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710116
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710115
          Length = 150

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EPFLFMSL 8
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>NP_001001954
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PFLFMSL 8
           PF+FM+L
Sbjct: 317 PFIFMTL 323
>NP_071351
          Length = 2752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    PFLFMSL 8
            P LFMSL
Sbjct: 2419 PLLFMSL 2425
>NP_003483
          Length = 261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   PFLFMSLQ 9
           P+LF+SL+
Sbjct: 139 PWLFLSLE 146
>NP_001136336
          Length = 2521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    PFLFMSL 8
            P LFMSL
Sbjct: 2190 PLLFMSL 2196
>XP_006721417
          Length = 2497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    PFLFMSL 8
            P LFMSL
Sbjct: 2166 PLLFMSL 2172
>XP_006721416
          Length = 2504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    PFLFMSL 8
            P LFMSL
Sbjct: 2173 PLLFMSL 2179
>NP_002652
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EPFLFM 6
           EPFLF+
Sbjct: 282 EPFLFV 287
>NP_005631
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EPFLFM 6
           EPFLF+
Sbjct: 652 EPFLFI 657
>NP_115612
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 484 EPYEFVSLE 492
>NP_067646
          Length = 568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EPFLFMSLQ 9
           EPF+  SLQ
Sbjct: 239 EPFIRCSLQ 247
>NP_065811
          Length = 1572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           +P+L MS+Q
Sbjct: 206 DPYLKMSIQ 214
>XP_006722591
          Length = 827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EPFLFM 6
           EPFLF+
Sbjct: 652 EPFLFI 657
>XP_006712712
          Length = 1414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EPFLFMSLQ 9
          +P+L MS+Q
Sbjct: 41 DPYLKMSIQ 49
>XP_006712711
          Length = 1448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EPFLFMSLQ 9
          +P+L MS+Q
Sbjct: 75 DPYLKMSIQ 83
>XP_006712710
          Length = 1528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           +P+L MS+Q
Sbjct: 206 DPYLKMSIQ 214
>XP_006712709
          Length = 1579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           +P+L MS+Q
Sbjct: 206 DPYLKMSIQ 214
>XP_006711542
          Length = 505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EPFLFMSLQ 9
           EPF+  SLQ
Sbjct: 277 EPFIRCSLQ 285
>XP_006711541
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EPFLFMSLQ 9
           EPF+  SLQ
Sbjct: 277 EPFIRCSLQ 285
>XP_005245460
          Length = 606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EPFLFMSLQ 9
           EPF+  SLQ
Sbjct: 277 EPFIRCSLQ 285
>XP_006711019
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EPFLFMSLQ 9
          EP+ F+SL+
Sbjct: 70 EPYEFVSLE 78
>XP_006711017
          Length = 981

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 417 EPYEFVSLE 425
>XP_005246067
          Length = 982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 484 EPYEFVSLE 492
>XP_005246066
          Length = 983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 484 EPYEFVSLE 492
>XP_006711015
          Length = 996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 484 EPYEFVSLE 492
>XP_006711014
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 483 EPYEFVSLE 491
>XP_006711013
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 483 EPYEFVSLE 491
>XP_006711012
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EPFLFMSLQ 9
           EP+ F+SL+
Sbjct: 484 EPYEFVSLE 492
>NP_115971
          Length = 1604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EPFLFMSL 8
           +PF F+SL
Sbjct: 904 DPFNFLSL 911
>NP_004496
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EPFLFMSL 8
           +PF F+SL
Sbjct: 702 DPFNFLSL 709
>XP_005256902
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EPFLFMSL 8
           +PF F+SL
Sbjct: 702 DPFNFLSL 709
>NP_001005486
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  EPFLFMS 7
          +PFLF++
Sbjct: 48 QPFLFLT 54
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.148    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,744
Number of extensions: 394
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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