Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_775740                                                              17    3301
NP_001138807                                                           17    3301
NP_001271311                                                           17    3301
XP_006720833                                                           17    3301
XP_005254845                                                           17    3301
XP_005254844                                                           17    3301
NP_004466                                                              17    4312
XP_005258010                                                           17    4312
XP_005258009                                                           17    4312
XP_005258007                                                           17    4312
NP_055972                                                              16    5631
NP_001138231                                                           16    5631
NP_001138230                                                           16    5631
NP_004809                                                              16    5631
NP_001189                                                              16    5631
NP_878911                                                              16    5631
NP_078831                                                              16    5631
NP_036294                                                              16    5631
XP_005271531                                                           16    5631
XP_005271530                                                           16    5631
XP_005271529                                                           16    5631
XP_006718866                                                           16    5631
XP_005271528                                                           16    5631
XP_006718865                                                           16    5631
XP_005271527                                                           16    5631
XP_005271526                                                           16    5631
XP_006718864                                                           16    5631
XP_005271525                                                           16    5631
XP_006718863                                                           16    5631
XP_006718862                                                           16    5631
XP_006718861                                                           16    5631
XP_006718860                                                           16    5631
XP_006718859                                                           16    5631
XP_005277737                                                           16    5631
XP_005267151                                                           16    5631
XP_006715613                                                           16    5631
NP_689705                                                              16    5631
NP_006195                                                              16    7355
NP_060854                                                              16    7355
NP_064615                                                              16    7355
NP_001185619                                                           16    7355
NP_001035754                                                           16    7355
NP_001186506                                                           16    7355
NP_064627                                                              15    9605
NP_079104                                                              15    9605
NP_001161047                                                           15    9605
NP_001269512                                                           15    9605
NP_001269514                                                           15    9605
NP_001269511                                                           15    9605
NP_001269513                                                           15    9605
NP_115724                                                              15    9605
NP_001265166                                                           15    9605
NP_055069                                                              15    9605
XP_006719258                                                           15    9605
XP_005268620                                                           15    9605
XP_005268619                                                           15    9605
XP_005251638                                                           15    9605
XP_006713328                                                           15    9605
XP_006713327                                                           15    9605
XP_006713326                                                           15    9605
XP_006713325                                                           15    9605
XP_006713324                                                           15    9605
XP_005265385                                                           15    9605
XP_006710765                                                           15    9605
XP_005244815                                                           15    9605
>NP_775740
          Length = 375

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EKE LA+LE
Sbjct: 176 EKENLAILE 184
>NP_001138807
          Length = 359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EKE LA+LE
Sbjct: 160 EKENLAILE 168
>NP_001271311
          Length = 340

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EKE LA+LE
Sbjct: 141 EKENLAILE 149
>XP_006720833
          Length = 235

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EKE LA+LE
Sbjct: 176 EKENLAILE 184
>XP_005254845
          Length = 296

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EKE LA+LE
Sbjct: 176 EKENLAILE 184
>XP_005254844
          Length = 314

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EKE LA+LE
Sbjct: 176 EKENLAILE 184
>NP_004466
          Length = 428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  EKELLAV 7
          EKELLAV
Sbjct: 80 EKELLAV 86
>XP_005258010
          Length = 351

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1 EKELLAV 7
         EKELLAV
Sbjct: 3 EKELLAV 9
>XP_005258009
          Length = 379

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  EKELLAV 7
          EKELLAV
Sbjct: 31 EKELLAV 37
>XP_005258007
          Length = 428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  EKELLAV 7
          EKELLAV
Sbjct: 80 EKELLAV 86
>NP_055972
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 883 EKEKLTVLE 891
>NP_001138231
          Length = 1319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 883 EKEKLTVLE 891
>NP_001138230
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 883 EKEKLTVLE 891
>NP_004809
          Length = 820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KELLAVLE 9
           K+LLA+LE
Sbjct: 653 KKLLAILE 660
>NP_001189
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EKELLAVL 8
           EKE+LAV+
Sbjct: 756 EKEILAVV 763
>NP_878911
          Length = 691

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EKELLAVL 8
           EKE+LAV+
Sbjct: 622 EKEILAVV 629
>NP_078831
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EK+LLA LE
Sbjct: 178 EKKLLASLE 186
>NP_036294
          Length = 539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EK+LLA LE
Sbjct: 178 EKKLLASLE 186
>XP_005271531
          Length = 1365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 929 EKEKLTVLE 937
>XP_005271530
          Length = 1376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 929 EKEKLTVLE 937
>XP_005271529
          Length = 1391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 929 EKEKLTVLE 937
>XP_006718866
          Length = 1408

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 972 EKEKLTVLE 980
>XP_005271528
          Length = 1412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 929 EKEKLTVLE 937
>XP_006718865
          Length = 1419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 972 EKEKLTVLE 980
>XP_005271527
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 929 EKEKLTVLE 937
>XP_005271526
          Length = 1427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 929 EKEKLTVLE 937
>XP_006718864
          Length = 1434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 972 EKEKLTVLE 980
>XP_005271525
          Length = 1438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 929 EKEKLTVLE 937
>XP_006718863
          Length = 1455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 972 EKEKLTVLE 980
>XP_006718862
          Length = 1466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 972 EKEKLTVLE 980
>XP_006718861
          Length = 1481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 972 EKEKLTVLE 980
>XP_006718860
          Length = 1538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 972 EKEKLTVLE 980
>XP_006718859
          Length = 1539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 925 EKEKLTVLE 933
>XP_005277737
          Length = 1585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKELLAVLE 9
           EKE L VLE
Sbjct: 971 EKEKLTVLE 979
>XP_005267151
          Length = 667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EKELLAVL 8
           EKE+LAV+
Sbjct: 598 EKEILAVV 605
>XP_006715613
          Length = 796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EKELLAVL 8
           EKE+LAV+
Sbjct: 727 EKEILAVV 734
>NP_689705
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           E+ELLA LE
Sbjct: 408 EEELLAQLE 416
>NP_006195
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EKELLAVLE 9
           EK+L+A+L+
Sbjct: 487 EKQLVAILK 495
>NP_060854
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           + ELLAV+E
Sbjct: 200 QAELLAVIE 208
>NP_064615
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           E+EL A+LE
Sbjct: 305 EEELQAILE 313
>NP_001185619
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           E+EL A+LE
Sbjct: 305 EEELQAILE 313
>NP_001035754
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           E+EL A+LE
Sbjct: 305 EEELQAILE 313
>NP_001186506
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           + ELLAV+E
Sbjct: 404 QAELLAVIE 412
>NP_064627
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>NP_079104
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EK++L +LE
Sbjct: 188 EKKILKILE 196
>NP_001161047
          Length = 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EKELLAVLE 9
          EK++L +LE
Sbjct: 43 EKKILKILE 51
>NP_001269512
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EKELLAV 7
           EKE+LAV
Sbjct: 161 EKEVLAV 167
>NP_001269514
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EKELLAV 7
           EKE+LAV
Sbjct: 170 EKEVLAV 176
>NP_001269511
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EKELLAV 7
           EKE+LAV
Sbjct: 170 EKEVLAV 176
>NP_001269513
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  EKELLAV 7
          EKE+LAV
Sbjct: 69 EKEVLAV 75
>NP_115724
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EKELLAV 7
           EKE+LAV
Sbjct: 170 EKEVLAV 176
>NP_001265166
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KEL AVLE
Sbjct: 130 KELPAVLE 137
>NP_055069
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KEL AVLE
Sbjct: 390 KELPAVLE 397
>XP_006719258
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KEL AVLE
Sbjct: 130 KELPAVLE 137
>XP_005268620
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KEL AVLE
Sbjct: 287 KELPAVLE 294
>XP_005268619
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KEL AVLE
Sbjct: 287 KELPAVLE 294
>XP_005251638
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EKELLAVLE 9
           EK++L +LE
Sbjct: 188 EKKILKILE 196
>XP_006713328
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_006713327
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KE+L VLE
Sbjct: 564 KEILKVLE 571
>XP_006713326
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_006713325
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_006713324
          Length = 1285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_005265385
          Length = 1291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KELLAVLE 9
           KE+L VLE
Sbjct: 832 KEILKVLE 839
>XP_006710765
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  EKELLAV 7
          EKE+LAV
Sbjct: 69 EKEVLAV 75
>XP_005244815
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EKELLAV 7
           EKE+LAV
Sbjct: 170 EKEVLAV 176
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.131    0.293 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 553,909
Number of extensions: 991
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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