Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
XP_006726410                                                           19     665
XP_006711719                                                           19     665
XP_006711718                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006711164                                                           19     665
XP_006710143                                                           19     665
XP_006710142                                                           19     665
XP_006710141                                                           19     665
NP_110443                                                              17    3301
XP_006710993                                                           17    3301
XP_005271292                                                           17    3301
XP_005271291                                                           17    3301
XP_006710992                                                           17    3301
NP_056211                                                              17    4312
NP_001269271                                                           17    4312
NP_001253970                                                           17    4312
NP_001253971                                                           17    4312
XP_006713630                                                           17    4312
XP_006713629                                                           17    4312
XP_006713628                                                           17    4312
XP_006713627                                                           17    4312
XP_005276254                                                           16    5631
XP_006726433                                                           16    5631
XP_006726432                                                           16    5631
XP_006726431                                                           16    5631
XP_005277553                                                           16    5631
XP_006711780                                                           16    5631
XP_006711779                                                           16    5631
XP_006711778                                                           16    5631
NP_055893                                                              16    7355
NP_004597                                                              15    9605
NP_001273003                                                           15    9605
NP_620278                                                              15    9605
NP_000579                                                              15    9605
NP_055968                                                              15    9605
NP_055146                                                              15    9605
NP_001277188                                                           15    9605
NP_066580                                                              15    9605
XP_006724745                                                           15    9605
XP_006724744                                                           15    9605
XP_005262354                                                           15    9605
XP_006724743                                                           15    9605
XP_005262353                                                           15    9605
XP_005262352                                                           15    9605
XP_005253535                                                           15    9605
XP_005253534                                                           15    9605
XP_005253531                                                           15    9605
XP_006715490                                                           15    9605
XP_005248760                                                           15    9605
XP_005248759                                                           15    9605
XP_006715489                                                           15    9605
XP_005248758                                                           15    9605
XP_005262932                                                           15    9605
NP_602307                                                              15    9605
NP_057645                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1470 EDLLRSNDI 1478
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1514 EDLLRSNDI 1522
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1514 EDLLRSNDI 1522
>XP_006726410
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1317 EDLLRSNDI 1325
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1470 EDLLRSNDI 1478
>XP_006711718
          Length = 1436

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EDLLMSNDI 9
           EDLL SNDI
Sbjct: 521 EDLLRSNDI 529
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1470 EDLLRSNDI 1478
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1579 EDLLRSNDI 1587
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1513 EDLLRSNDI 1521
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1514 EDLLRSNDI 1522
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1517 EDLLRSNDI 1525
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1567 EDLLRSNDI 1575
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1579 EDLLRSNDI 1587
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1580 EDLLRSNDI 1588
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1676 EDLLRSNDI 1684
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1677 EDLLRSNDI 1685
>XP_006711164
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDLLMSNDI 9
            EDLL SNDI
Sbjct: 1317 EDLLRSNDI 1325
>XP_006710143
          Length = 562

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EDLLMSNDI 9
           EDLL SNDI
Sbjct: 356 EDLLRSNDI 364
>XP_006710142
          Length = 671

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EDLLMSNDI 9
           EDLL SNDI
Sbjct: 465 EDLLRSNDI 473
>XP_006710141
          Length = 672

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EDLLMSNDI 9
           EDLL SNDI
Sbjct: 466 EDLLRSNDI 474
>NP_110443
          Length = 541

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DLLMSNDI 9
           D+LMS+DI
Sbjct: 318 DILMSSDI 325
>XP_006710993
          Length = 352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DLLMSNDI 9
           D+LMS+DI
Sbjct: 318 DILMSSDI 325
>XP_005271292
          Length = 451

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DLLMSNDI 9
           D+LMS+DI
Sbjct: 318 DILMSSDI 325
>XP_005271291
          Length = 484

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DLLMSNDI 9
           D+LMS+DI
Sbjct: 318 DILMSSDI 325
>XP_006710992
          Length = 503

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DLLMSNDI 9
           D+LMS+DI
Sbjct: 318 DILMSSDI 325
>NP_056211
          Length = 659

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 576 KDLIMTND 583
>NP_001269271
          Length = 600

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 517 KDLIMTND 524
>NP_001253970
          Length = 642

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 559 KDLIMTND 566
>NP_001253971
          Length = 606

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 523 KDLIMTND 530
>XP_006713630
          Length = 620

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 590 KDLIMTND 597
>XP_006713629
          Length = 631

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 548 KDLIMTND 555
>XP_006713628
          Length = 659

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 576 KDLIMTND 583
>XP_006713627
          Length = 673

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EDLLMSND 8
           +DL+M+ND
Sbjct: 590 KDLIMTND 597
>XP_005276254
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>XP_006726433
          Length = 164

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>XP_006726432
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>XP_006726431
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>XP_005277553
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>XP_006711780
          Length = 164

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>XP_006711779
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>XP_006711778
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          E+LL SN+I
Sbjct: 23 EELLQSNNI 31
>NP_055893
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EDLLMSN 7
           EDLLMS+
Sbjct: 237 EDLLMSH 243
>NP_004597
          Length = 1893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1735 EDLLMS 1740
>NP_001273003
          Length = 1895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1737 EDLLMS 1742
>NP_620278
          Length = 1872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1714 EDLLMS 1719
>NP_000579
          Length = 152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  EDLLMSNDI 9
          +D+LM N++
Sbjct: 64 QDILMENNL 72
>NP_055968
          Length = 2039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EDLLMSN 7
            ED+LM N
Sbjct: 1741 EDILMQN 1747
>NP_055146
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EDLLMSNDI 9
           E+LL+SN +
Sbjct: 295 EELLLSNAV 303
>NP_001277188
          Length = 1951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EDLLMSN 7
            ED+LM N
Sbjct: 1653 EDILMQN 1659
>NP_066580
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EDLLMSNDI 9
           +DL + NDI
Sbjct: 427 QDLYVENDI 435
>XP_006724745
          Length = 1800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1642 EDLLMS 1647
>XP_006724744
          Length = 1851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1766 EDLLMS 1771
>XP_005262354
          Length = 1906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1748 EDLLMS 1753
>XP_006724743
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1766 EDLLMS 1771
>XP_005262353
          Length = 1926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1768 EDLLMS 1773
>XP_005262352
          Length = 1927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EDLLMS 6
            EDLLMS
Sbjct: 1769 EDLLMS 1774
>XP_005253535
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EDLLMSNDI 9
           +DL + NDI
Sbjct: 425 QDLYVENDI 433
>XP_005253534
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EDLLMSNDI 9
           +DL + NDI
Sbjct: 407 QDLYVENDI 415
>XP_005253531
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EDLLMSNDI 9
           +DL + NDI
Sbjct: 427 QDLYVENDI 435
>XP_006715490
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   EDLLMSN 7
           ED+LM N
Sbjct: 883 EDILMQN 889
>XP_005248760
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EDLLMSN 7
            ED+LM N
Sbjct: 1010 EDILMQN 1016
>XP_005248759
          Length = 1951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EDLLMSN 7
            ED+LM N
Sbjct: 1653 EDILMQN 1659
>XP_006715489
          Length = 2039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EDLLMSN 7
            ED+LM N
Sbjct: 1741 EDILMQN 1747
>XP_005248758
          Length = 2039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EDLLMSN 7
            ED+LM N
Sbjct: 1741 EDILMQN 1747
>XP_005262932
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EDLLMSNDI 9
           E+LL+SN +
Sbjct: 295 EELLLSNAV 303
>NP_602307
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EDLLMSNDI 9
           +DL + NDI
Sbjct: 427 QDLYVENDI 435
>NP_057645
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EDLLMSNDI 9
           ED+  +NDI
Sbjct: 104 EDIQQNNDI 112
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.136    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 456,601
Number of extensions: 772
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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