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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     299
NP_001075109                                                           20     299
NP_036423                                                              18    1482
XP_006719768                                                           18    1482
NP_001269109                                                           18    1935
NP_006237                                                              18    1935
NP_001269111                                                           18    1935
NP_001269110                                                           18    1935
NP_001269108                                                           18    1935
NP_997244                                                              16    7355
NP_110447                                                              16    7355
NP_997300                                                              16    7355
NP_001269886                                                           16    7355
NP_000821                                                              16    7355
NP_783300                                                              16    7355
NP_001161707                                                           16    7355
XP_005261001                                                           16    7355
XP_005261000                                                           16    7355
XP_005260999                                                           16    7355
XP_006724054                                                           16    7355
XP_006715287                                                           16    7355
XP_006715286                                                           16    7355
NP_001243465                                                           15    9605
NP_062828                                                              15    9605
NP_001186711                                                           15    9605
XP_006719049                                                           15    9605

>NP_008835
          Length = 4128

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DYVAVSRGS 9
            DYVAV+RGS
Sbjct: 4076 DYVAVARGS 4084



>NP_001075109
          Length = 4097

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    DYVAVSRGS 9
            DYVAV+RGS
Sbjct: 4045 DYVAVARGS 4053



>NP_036423
          Length = 2120

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DYVAVSRGS 9
           DY AV+RGS
Sbjct: 139 DYEAVARGS 147



>XP_006719768
          Length = 2120

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DYVAVSRGS 9
           DY AV+RGS
Sbjct: 139 DYEAVARGS 147



>NP_001269109
          Length = 462

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DYVAVSRG 8
           DY+ +SRG
Sbjct: 98  DYITISRG 105



>NP_006237
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DYVAVSRG 8
           DY+ +SRG
Sbjct: 98  DYITISRG 105



>NP_001269111
          Length = 391

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DYVAVSRG 8
          DY+ +SRG
Sbjct: 22 DYITISRG 29



>NP_001269110
          Length = 391

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DYVAVSRG 8
          DY+ +SRG
Sbjct: 22 DYITISRG 29



>NP_001269108
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DYVAVSRG 8
           DY+ +SRG
Sbjct: 98  DYITISRG 105



>NP_997244
          Length = 3169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DYVAVSR 7
            DYV +SR
Sbjct: 2060 DYVGISR 2066



>NP_110447
          Length = 957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DYVAVSR 7
           DY+A+S+
Sbjct: 196 DYIAISK 202



>NP_997300
          Length = 320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DYVAVSRGS 9
           +Y+A++RG+
Sbjct: 155 NYIAMNRGA 163



>NP_001269886
          Length = 284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DYVAVSRGS 9
           +Y+A++RG+
Sbjct: 119 NYIAMNRGA 127



>NP_000821
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DYVAVSR 7
           DY A+SR
Sbjct: 153 DYAAISR 159



>NP_783300
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DYVAVSR 7
           DY A+SR
Sbjct: 153 DYAAISR 159



>NP_001161707
          Length = 2139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DYVAVSR 7
            DYV +SR
Sbjct: 2063 DYVGISR 2069



>XP_005261001
          Length = 903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DYVAVSR 7
           DY A+SR
Sbjct: 153 DYAAISR 159



>XP_005261000
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DYVAVSR 7
           DY A+SR
Sbjct: 153 DYAAISR 159



>XP_005260999
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DYVAVSR 7
           DY A+SR
Sbjct: 153 DYAAISR 159



>XP_006724054
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DYVAVSR 7
           DY A+SR
Sbjct: 153 DYAAISR 159



>XP_006715287
          Length = 615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DYVAVSR 7
           DY+A+S+
Sbjct: 196 DYIAISK 202



>XP_006715286
          Length = 945

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DYVAVSR 7
           DY+A+S+
Sbjct: 196 DYIAISK 202



>NP_001243465
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DYVAVSRG 8
           DY+ V RG
Sbjct: 335 DYLTVRRG 342



>NP_062828
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DYVAVSRG 8
           DY+ V RG
Sbjct: 344 DYLTVRRG 351



>NP_001186711
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VAVSRGS 9
          +AVSRGS
Sbjct: 21 LAVSRGS 27



>XP_006719049
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DYVAVSRG 8
           DY+ V RG
Sbjct: 207 DYLTVRRG 214



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.127    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 446,244
Number of extensions: 771
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)