Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
XP_006726436                                                           19     665
XP_006726410                                                           19     665
XP_006711784                                                           19     665
XP_006711719                                                           19     665
XP_006711718                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006711164                                                           19     665
XP_005276114                                                           19     665
XP_006710122                                                           19     665
NP_006209                                                              17    3301
NP_001103132                                                           17    3301
XP_006713721                                                           17    3301
NP_060868                                                              17    4312
XP_005265376                                                           17    4312
XP_005265375                                                           17    4312
NP_001002907                                                           16    5631
NP_055105                                                              16    7355
NP_000709                                                              16    7355
NP_001230741                                                           16    7355
XP_006717089                                                           16    7355
XP_006717088                                                           16    7355
NP_001171655                                                           15    9605
NP_000346                                                              15    9605
NP_775105                                                              15    9605
NP_001036148                                                           15    9605
NP_001008781                                                           15    9605
XP_006715505                                                           15    9605
XP_006715504                                                           15    9605
XP_006715503                                                           15    9605
XP_006715502                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2217 DVLKKARTN 2225
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2323 DVLKKARTN 2331
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2323 DVLKKARTN 2331
>XP_006726436
          Length = 178

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DVLKKAMTN 9
           DVLKKA TN
Sbjct: 101 DVLKKARTN 109
>XP_006726410
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2064 DVLKKARTN 2072
>XP_006711784
          Length = 178

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DVLKKAMTN 9
           DVLKKA TN
Sbjct: 101 DVLKKARTN 109
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2279 DVLKKARTN 2287
>XP_006711718
          Length = 1436

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 1330 DVLKKARTN 1338
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2279 DVLKKARTN 2287
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2388 DVLKKARTN 2396
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2322 DVLKKARTN 2330
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2323 DVLKKARTN 2331
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2326 DVLKKARTN 2334
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2367 DVLKKARTN 2375
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2376 DVLKKARTN 2384
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2388 DVLKKARTN 2396
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2389 DVLKKARTN 2397
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2486 DVLKKARTN 2494
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2486 DVLKKARTN 2494
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2406 DVLKKARTN 2414
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2486 DVLKKARTN 2494
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2447 DVLKKARTN 2455
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2486 DVLKKARTN 2494
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2485 DVLKKARTN 2493
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2486 DVLKKARTN 2494
>XP_006711164
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            DVLKKA TN
Sbjct: 2064 DVLKKARTN 2072
>XP_005276114
          Length = 134

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  DVLKKAMTN 9
          DVLKKA TN
Sbjct: 71 DVLKKARTN 79
>XP_006710122
          Length = 126

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DVLKKAMTN 9
           DVLKKA TN
Sbjct: 101 DVLKKARTN 109
>NP_006209
          Length = 1068

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLKKAMTN 9
           +LKKA+TN
Sbjct: 653 LLKKALTN 660
>NP_001103132
          Length = 4284

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLKKAMTN 9
           D+++KAM N
Sbjct: 559 DIMEKAMVN 567
>XP_006713721
          Length = 1068

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLKKAMTN 9
           +LKKA+TN
Sbjct: 653 LLKKALTN 660
>NP_060868
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLKKAMTN 9
           DVL+ AM N
Sbjct: 569 DVLRNAMVN 577
>XP_005265376
          Length = 877

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLKKAMTN 9
           DVL+ AM N
Sbjct: 569 DVLRNAMVN 577
>XP_005265375
          Length = 1085

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLKKAMTN 9
           DVL+ AM N
Sbjct: 563 DVLRNAMVN 571
>NP_001002907
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVLKKAMTN 9
           D LK+ +TN
Sbjct: 305 DALKRTLTN 313
>NP_055105
          Length = 1098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLKKAMTN 9
           DV+KK+M +
Sbjct: 883 DVIKKSMVD 891
>NP_000709
          Length = 2339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVLKKAMT 8
           DVLK+A T
Sbjct: 414 DVLKRAAT 421
>NP_001230741
          Length = 2237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVLKKAMT 8
           DVLK+A T
Sbjct: 414 DVLKRAAT 421
>XP_006717089
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLKKAMTN 9
           DV+KK+M +
Sbjct: 438 DVIKKSMVD 446
>XP_006717088
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLKKAMTN 9
           DV+KK+M +
Sbjct: 809 DVIKKSMVD 817
>NP_001171655
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DVLKKA 6
           DVLKKA
Sbjct: 330 DVLKKA 335
>NP_000346
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DVLKKA 6
           DVLKKA
Sbjct: 357 DVLKKA 362
>NP_775105
          Length = 1659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            D++ KA+T+
Sbjct: 1546 DIISKALTD 1554
>NP_001036148
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            D++ KA+T+
Sbjct: 1542 DIISKALTD 1550
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LKKAMTN 9
           LKK++TN
Sbjct: 635 LKKSLTN 641
>XP_006715505
          Length = 1673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            D++ KA+T+
Sbjct: 1542 DIISKALTD 1550
>XP_006715504
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            D++ KA+T+
Sbjct: 1542 DIISKALTD 1550
>XP_006715503
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            D++ KA+T+
Sbjct: 1542 DIISKALTD 1550
>XP_006715502
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    DVLKKAMTN 9
            D++ KA+T+
Sbjct: 1542 DIISKALTD 1550
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.121    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 353,980
Number of extensions: 494
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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