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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              19     869
NP_055099                                                              17    2528
NP_001014839                                                           17    2528
NP_001014841                                                           17    2528
NP_001138482                                                           16    5631
NP_001254505                                                           16    5631
NP_694942                                                              16    5631
NP_444281                                                              16    7355
NP_055855                                                              16    7355
NP_689884                                                              16    7355
NP_001171471                                                           16    7355
NP_783165                                                              16    7355
NP_001269076                                                           16    7355
NP_060296                                                              16    7355
NP_001185839                                                           16    7355
NP_001015050                                                           15    9605
NP_001182152                                                           15    9605
NP_000632                                                              15    9605
XP_005247258                                                           15    9605
XP_006713591                                                           15    9605

>NP_004251
          Length = 1208

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTEQIAALL 9
           DTE+IAALL
Sbjct: 712 DTERIAALL 720



>NP_055099
          Length = 729

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  DTEQIAALL 9
          D+EQ AALL
Sbjct: 49 DSEQFAALL 57



>NP_001014839
          Length = 729

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  DTEQIAALL 9
          D+EQ AALL
Sbjct: 49 DSEQFAALL 57



>NP_001014841
          Length = 712

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  DTEQIAALL 9
          D+EQ AALL
Sbjct: 32 DSEQFAALL 40



>NP_001138482
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTEQIAALL 9
           DTE++ ALL
Sbjct: 251 DTEEMEALL 259



>NP_001254505
          Length = 1118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEQIAALL 9
           TEQ+AAL+
Sbjct: 144 TEQLAALV 151



>NP_694942
          Length = 1123

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEQIAALL 9
           TEQ+AAL+
Sbjct: 144 TEQLAALV 151



>NP_444281
          Length = 335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DTEQIAALL 9
           D EQ AALL
Sbjct: 252 DAEQQAALL 260



>NP_055855
          Length = 2098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DTEQIA 6
           DTEQIA
Sbjct: 476 DTEQIA 481



>NP_689884
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DTEQIA 6
           DTEQIA
Sbjct: 379 DTEQIA 384



>NP_001171471
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DTEQIA 6
           DTEQIA
Sbjct: 476 DTEQIA 481



>NP_783165
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  EQIAALL 9
          EQ+AALL
Sbjct: 14 EQVAALL 20



>NP_001269076
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTEQIAALL 9
          DT++ AALL
Sbjct: 52 DTKEAAALL 60



>NP_060296
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTEQIAALL 9
          DT++ AALL
Sbjct: 52 DTKEAAALL 60



>NP_001185839
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTEQIAALL 9
           DT++ AALL
Sbjct: 129 DTKEAAALL 137



>NP_001015050
          Length = 187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DTEQIAAL 8
           D+E++AAL
Sbjct: 108 DSEELAAL 115



>NP_001182152
          Length = 207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DTEQIAAL 8
           D+E++AAL
Sbjct: 128 DSEELAAL 135



>NP_000632
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTEQIAALL 9
          DT Q+AA L
Sbjct: 52 DTRQLAAQL 60



>XP_005247258
          Length = 207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DTEQIAAL 8
           D+E++AAL
Sbjct: 128 DSEELAAL 135



>XP_006713591
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DTEQIAAL 8
           D+E++AAL
Sbjct: 129 DSEELAAL 136



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.128    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,871
Number of extensions: 506
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)