Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              18    1135
NP_005913                                                              18    1135
XP_005267046                                                           18    1135
XP_005267045                                                           18    1135
NP_065955                                                              16    7355
NP_001154826                                                           16    7355
NP_055864                                                              16    7355
XP_006723364                                                           16    7355
XP_005259166                                                           16    7355
XP_005259165                                                           16    7355
XP_005259164                                                           16    7355
XP_006714495                                                           16    7355
NP_055928                                                              15    9605
NP_056366                                                              15    9605
NP_001273760                                                           15    9605
NP_001273759                                                           15    9605
NP_001259                                                              15    9605
XP_005256618                                                           15    9605
XP_005256617                                                           15    9605
XP_005266301                                                           15    9605
XP_005266299                                                           15    9605
XP_006719822                                                           15    9605
XP_006719821                                                           15    9605
XP_005265092                                                           15    9605
XP_005265091                                                           15    9605
>NP_006715
          Length = 1558

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRLVSIAAE 9
            DRL SIAAE
Sbjct: 1183 DRLASIAAE 1191
>NP_005913
          Length = 1608

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRLVSIAAE 9
            DRL SIAAE
Sbjct: 1233 DRLASIAAE 1241
>XP_005267046
          Length = 1554

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRLVSIAAE 9
            DRL SIAAE
Sbjct: 1179 DRLASIAAE 1187
>XP_005267045
          Length = 1604

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DRLVSIAAE 9
            DRL SIAAE
Sbjct: 1229 DRLASIAAE 1237
>NP_065955
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DRLVS+ A
Sbjct: 428 DRLVSVRA 435
>NP_001154826
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DRLVS+ A
Sbjct: 403 DRLVSVRA 410
>NP_055864
          Length = 914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLVSIAAE 9
           R+VSIA+E
Sbjct: 176 RIVSIASE 183
>XP_006723364
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DRLVS+ A
Sbjct: 403 DRLVSVRA 410
>XP_005259166
          Length = 595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DRLVS+ A
Sbjct: 428 DRLVSVRA 435
>XP_005259165
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DRLVS+ A
Sbjct: 428 DRLVSVRA 435
>XP_005259164
          Length = 754

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DRLVS+ A
Sbjct: 403 DRLVSVRA 410
>XP_006714495
          Length = 257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLVSIAAE 9
           RL+S+AA+
Sbjct: 97  RLISVAAQ 104
>NP_055928
          Length = 2961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           D LVS+AA
Sbjct: 934 DTLVSVAA 941
>NP_056366
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLVSIA 7
           DRLVSI+
Sbjct: 248 DRLVSIS 254
>NP_001273760
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DR++ IAA
Sbjct: 284 DRIIEIAA 291
>NP_001273759
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DR++ IAA
Sbjct: 313 DRIIEIAA 320
>NP_001259
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DR++ IAA
Sbjct: 308 DRIIEIAA 315
>XP_005256618
          Length = 2962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           D LVS+AA
Sbjct: 935 DTLVSVAA 942
>XP_005256617
          Length = 2966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           D LVS+AA
Sbjct: 935 DTLVSVAA 942
>XP_005266301
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DR++ IAA
Sbjct: 284 DRIIEIAA 291
>XP_005266299
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DR++ IAA
Sbjct: 308 DRIIEIAA 315
>XP_006719822
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DR++ IAA
Sbjct: 308 DRIIEIAA 315
>XP_006719821
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DRLVSIAA 8
           DR++ IAA
Sbjct: 318 DRIIEIAA 325
>XP_005265092
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  DRLVSIA 7
          DRLVSI+
Sbjct: 70 DRLVSIS 76
>XP_005265091
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLVSIA 7
           DRLVSI+
Sbjct: 185 DRLVSIS 191
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.129    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 238,595
Number of extensions: 308
Number of successful extensions: 25
Number of sequences better than 10000.0: 25
Number of HSP's gapped: 25
Number of HSP's successfully gapped: 25
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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