Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              18    1135
XP_006713721                                                           18    1135
XP_006724601                                                           18    1935
NP_001816                                                              17    4312
NP_065880                                                              17    4312
NP_001193486                                                           17    4312
XP_005251580                                                           17    4312
XP_005248477                                                           17    4312
NP_001093206                                                           17    4312
NP_001093205                                                           17    4312
NP_036370                                                              16    5631
NP_001135970                                                           16    5631
NP_112503                                                              16    5631
NP_000094                                                              16    5631
NP_940953                                                              16    5631
NP_061198                                                              16    5631
NP_997254                                                              16    5631
XP_006720670                                                           16    5631
XP_006720469                                                           16    5631
XP_005254248                                                           16    5631
XP_005254247                                                           16    5631
XP_005269720                                                           16    5631
XP_006717800                                                           16    5631
XP_005252508                                                           16    5631
XP_006717511                                                           16    5631
XP_005252507                                                           16    5631
XP_005273179                                                           16    5631
XP_006711367                                                           16    5631
XP_005273178                                                           16    5631
NP_006653                                                              16    7355
NP_066270                                                              16    7355
NP_001191957                                                           16    7355
NP_059136                                                              16    7355
NP_001015001                                                           16    7355
NP_783165                                                              16    7355
NP_056081                                                              16    7355
NP_001247420                                                           16    7355
NP_001193856                                                           16    7355
XP_006723821                                                           16    7355
XP_006723820                                                           16    7355
XP_006723819                                                           16    7355
XP_005254555                                                           16    7355
XP_005254207                                                           16    7355
XP_005269084                                                           16    7355
XP_005269083                                                           16    7355
XP_006715067                                                           16    7355
XP_005270453                                                           16    7355
XP_005270452                                                           16    7355
XP_005270451                                                           16    7355
NP_006836                                                              16    7355
NP_005742                                                              15    9605
NP_671714                                                              15    9605
NP_115495                                                              15    9605
NP_006634                                                              15    9605
NP_001034796                                                           15    9605
NP_001034797                                                           15    9605
XP_005266108                                                           15    9605
XP_005266107                                                           15    9605
XP_006715890                                                           15    9605
XP_005250160                                                           15    9605
XP_005250159                                                           15    9605
NP_112486                                                              15    9605
>NP_006209
          Length = 1068

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           D LSEITEQ
Sbjct: 538 DPLSEITEQ 546
>XP_006713721
          Length = 1068

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           D LSEITEQ
Sbjct: 538 DPLSEITEQ 546
>XP_006724601
          Length = 1020

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           DRLSEI E+
Sbjct: 786 DRLSEIPEE 794
>NP_001816
          Length = 419

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSE+TEQ
Sbjct: 209 KLSEMTEQ 216
>NP_065880
          Length = 1423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RLSEITEQ 9
            +LSEITE+
Sbjct: 1344 KLSEITEE 1351
>NP_001193486
          Length = 1386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RLSEITEQ 9
            +LSEITE+
Sbjct: 1307 KLSEITEE 1314
>XP_005251580
          Length = 1422

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RLSEITEQ 9
            +LSEITE+
Sbjct: 1343 KLSEITEE 1350
>XP_005248477
          Length = 536

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSE+TEQ
Sbjct: 326 KLSEMTEQ 333
>NP_001093206
          Length = 419

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSE+TEQ
Sbjct: 209 KLSEMTEQ 216
>NP_001093205
          Length = 419

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSE+TEQ
Sbjct: 209 KLSEMTEQ 216
>NP_036370
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSEITE+
Sbjct: 506 KLSEITEK 513
>NP_001135970
          Length = 452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSEITE+
Sbjct: 211 KLSEITEK 218
>NP_112503
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRLSEITEQ 9
           DRL E+T +
Sbjct: 173 DRLEEVTNE 181
>NP_000094
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRLSEITEQ 9
           DRL E+T +
Sbjct: 173 DRLEEVTNE 181
>NP_940953
          Length = 1907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DRLSEITEQ 9
            DR+ ++TEQ
Sbjct: 1206 DRVYQVTEQ 1214
>NP_061198
          Length = 1742

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    DRLSEITEQ 9
            +++SEIT+Q
Sbjct: 1101 EKMSEITKQ 1109
>NP_997254
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DR+SEIT
Sbjct: 548 DRVSEIT 554
>XP_006720670
          Length = 1712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    DRLSEITEQ 9
            +++SEIT+Q
Sbjct: 1101 EKMSEITKQ 1109
>XP_006720469
          Length = 401

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  DRLSEITEQ 9
          DRL E+T +
Sbjct: 71 DRLEEVTNE 79
>XP_005254248
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRLSEITEQ 9
           DRL E+T +
Sbjct: 173 DRLEEVTNE 181
>XP_005254247
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DRLSEITEQ 9
           DRL E+T +
Sbjct: 173 DRLEEVTNE 181
>XP_005269720
          Length = 444

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSEITE+
Sbjct: 203 KLSEITEK 210
>XP_006717800
          Length = 696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           +LSEITE+
Sbjct: 455 KLSEITEK 462
>XP_005252508
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DR+SEIT
Sbjct: 548 DRVSEIT 554
>XP_006717511
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DR+SEIT
Sbjct: 548 DRVSEIT 554
>XP_005252507
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DR+SEIT
Sbjct: 548 DRVSEIT 554
>XP_005273179
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DRLSEITEQ 9
          DR+ ++TEQ
Sbjct: 84 DRVYQVTEQ 92
>XP_006711367
          Length = 1872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DRLSEITEQ 9
            DR+ ++TEQ
Sbjct: 1206 DRVYQVTEQ 1214
>XP_005273178
          Length = 1931

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    DRLSEITEQ 9
            DR+ ++TEQ
Sbjct: 1206 DRVYQVTEQ 1214
>NP_006653
          Length = 3230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DRLSEITEQ 9
            D+LSEI E+
Sbjct: 1967 DQLSEIIER 1975
>NP_066270
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLSEITE 8
           RLSE+TE
Sbjct: 208 RLSEMTE 214
>NP_001191957
          Length = 679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DRLSEI+
Sbjct: 645 DRLSEIS 651
>NP_059136
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DRLSEI+
Sbjct: 680 DRLSEIS 686
>NP_001015001
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLSEITE 8
           RLSE+TE
Sbjct: 208 RLSEMTE 214
>NP_783165
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           R+SE+TE+
Sbjct: 468 RVSELTEE 475
>NP_056081
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           + LSE+TE+
Sbjct: 504 EHLSELTEE 512
>NP_001247420
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           + LSE+TE+
Sbjct: 520 EHLSELTEE 528
>NP_001193856
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DRLSEIT 7
            DR+SE+T
Sbjct: 1580 DRISELT 1586
>XP_006723821
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           + LSE+TE+
Sbjct: 257 EHLSELTEE 265
>XP_006723820
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           + LSE+TE+
Sbjct: 257 EHLSELTEE 265
>XP_006723819
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           + LSE+TE+
Sbjct: 537 EHLSELTEE 545
>XP_005254555
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RLSEITE 8
          RLSE+TE
Sbjct: 49 RLSEMTE 55
>XP_005254207
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RLSEITE 8
          RLSE+TE
Sbjct: 49 RLSEMTE 55
>XP_005269084
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DRLSEI+
Sbjct: 588 DRLSEIS 594
>XP_005269083
          Length = 724

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DRLSEIT 7
           DRLSEI+
Sbjct: 690 DRLSEIS 696
>XP_006715067
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    DRLSEIT 7
            DR+SE+T
Sbjct: 1580 DRISELT 1586
>XP_005270453
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSEITEQ 9
           LSE+TEQ
Sbjct: 611 LSEMTEQ 617
>XP_005270452
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSEITEQ 9
           LSE+TEQ
Sbjct: 624 LSEMTEQ 630
>XP_005270451
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSEITEQ 9
           LSE+TEQ
Sbjct: 656 LSEMTEQ 662
>NP_006836
          Length = 725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSEITEQ 9
           LSE+TEQ
Sbjct: 665 LSEMTEQ 671
>NP_005742
          Length = 3907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           RLS+++EQ
Sbjct: 958 RLSDLSEQ 965
>NP_671714
          Length = 3899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           RLS+++EQ
Sbjct: 958 RLSDLSEQ 965
>NP_115495
          Length = 6306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DRLSEITE 8
            D+LSEI E
Sbjct: 5081 DQLSEIEE 5088
>NP_006634
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           DR+SE+ ++
Sbjct: 400 DRISEVKDE 408
>NP_001034796
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           DR+SE+ ++
Sbjct: 423 DRISEVKDE 431
>NP_001034797
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           DR+SE+ ++
Sbjct: 350 DRISEVKDE 358
>XP_005266108
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           DR+SE+ ++
Sbjct: 373 DRISEVKDE 381
>XP_005266107
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DRLSEITEQ 9
           DR+SE+ ++
Sbjct: 414 DRISEVKDE 422
>XP_006715890
          Length = 3860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           RLS+++EQ
Sbjct: 958 RLSDLSEQ 965
>XP_005250160
          Length = 3939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           RLS+++EQ
Sbjct: 958 RLSDLSEQ 965
>XP_005250159
          Length = 3952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLSEITEQ 9
           RLS+++EQ
Sbjct: 958 RLSDLSEQ 965
>NP_112486
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSEITEQ 9
           LSE+TE+
Sbjct: 117 LSEVTEE 123
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.122    0.288 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 367,205
Number of extensions: 667
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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