Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1482
NP_647593                                                              16    5631
NP_647601                                                              16    5631
NP_004296                                                              16    5631
NP_647598                                                              16    5631
NP_647600                                                              16    5631
NP_647596                                                              16    5631
NP_647595                                                              16    5631
NP_647594                                                              16    5631
NP_647599                                                              16    5631
NP_775859                                                              16    5631
NP_647597                                                              16    5631
XP_005263705                                                           16    5631
XP_005263704                                                           16    5631
XP_006712497                                                           16    5631
XP_006712496                                                           16    5631
XP_005263703                                                           16    5631
XP_006712495                                                           16    5631
XP_006712494                                                           16    5631
XP_006712493                                                           16    5631
XP_006712492                                                           16    5631
XP_006712491                                                           16    5631
XP_006712490                                                           16    5631
XP_005263702                                                           16    5631
XP_005263701                                                           16    5631
XP_006712489                                                           16    5631
XP_006712488                                                           16    5631
XP_005263700                                                           16    5631
XP_006712487                                                           16    5631
XP_005263699                                                           16    5631
NP_940992                                                              16    7355
NP_940993                                                              16    7355
NP_940991                                                              16    7355
NP_001719                                                              16    7355
NP_722540                                                              16    7355
NP_002608                                                              16    7355
NP_009117                                                              16    7355
NP_932349                                                              16    7355
NP_001180564                                                           16    7355
NP_001269920                                                           16    7355
NP_001269919                                                           16    7355
NP_001269917                                                           16    7355
NP_001269916                                                           16    7355
NP_001269918                                                           16    7355
NP_066284                                                              16    7355
XP_005260322                                                           16    7355
XP_005260321                                                           16    7355
XP_005260320                                                           16    7355
XP_006723758                                                           16    7355
XP_006723757                                                           16    7355
XP_006723756                                                           16    7355
XP_006723755                                                           16    7355
XP_006723754                                                           16    7355
XP_006723753                                                           16    7355
XP_005260319                                                           16    7355
XP_005259676                                                           16    7355
XP_006720309                                                           16    7355
XP_006720069                                                           16    7355
XP_006720068                                                           16    7355
NP_038466                                                              15    9605
NP_444295                                                              15    9605
NP_064516                                                              15    9605
NP_001800                                                              15    9605
NP_001032590                                                           15    9605
NP_005104                                                              15    9605
NP_001030598                                                           15    9605
NP_002004                                                              15    9605
NP_001512                                                              15    9605
NP_001157101                                                           15    9605
XP_005264330                                                           15    9605
XP_005264329                                                           15    9605
XP_005245404                                                           15    9605
XP_006710935                                                           15    9605
>NP_004251
          Length = 1208

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DQALLTLQQ 9
           DQALLTL Q
Sbjct: 685 DQALLTLLQ 693
>NP_647593
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_647601
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_004296
          Length = 454

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_647598
          Length = 482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_647600
          Length = 439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_647596
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_647595
          Length = 506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_647594
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_647599
          Length = 475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_775859
          Length = 1326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 661 DQALLTI 667
>NP_647597
          Length = 518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_005263705
          Length = 385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 96  DQALLTM 102
>XP_005263704
          Length = 424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712497
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712496
          Length = 455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_005263703
          Length = 470

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712495
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712494
          Length = 498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712493
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712492
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712491
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712490
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 96  DQALLTM 102
>XP_005263702
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 96  DQALLTM 102
>XP_005263701
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712489
          Length = 564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712488
          Length = 564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_005263700
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>XP_006712487
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 96  DQALLTM 102
>XP_005263699
          Length = 608

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DQALLTL 7
           DQALLT+
Sbjct: 120 DQALLTM 126
>NP_940992
          Length = 176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQALLTLQ 8
           DQA++TL+
Sbjct: 101 DQAIITLR 108
>NP_940993
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQALLTLQ 8
           DQA++TL+
Sbjct: 130 DQAIITLR 137
>NP_940991
          Length = 269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQALLTLQ 8
           DQA++TL+
Sbjct: 194 DQAIITLR 201
>NP_001719
          Length = 385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQALLTLQ 8
           DQA++TL+
Sbjct: 310 DQAIITLR 317
>NP_722540
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQALLTLQQ 9
           D+ALL L+Q
Sbjct: 107 DKALLPLEQ 115
>NP_002608
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQALLTLQQ 9
           D+ALL L+Q
Sbjct: 107 DKALLPLEQ 115
>NP_009117
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>NP_932349
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>NP_001180564
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 42 DQAVATLQ 49
>NP_001269920
          Length = 158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>NP_001269919
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>NP_001269917
          Length = 244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>NP_001269916
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>NP_001269918
          Length = 192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>NP_066284
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>XP_005260322
          Length = 1810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1268 EKALLALQQ 1276
>XP_005260321
          Length = 2365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1823 EKALLALQQ 1831
>XP_005260320
          Length = 2370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>XP_006723758
          Length = 2386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1844 EKALLALQQ 1852
>XP_006723757
          Length = 2404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>XP_006723756
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>XP_006723755
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>XP_006723754
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>XP_006723753
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>XP_005260319
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DQALLTLQQ 9
            ++ALL LQQ
Sbjct: 1900 EKALLALQQ 1908
>XP_005259676
          Length = 269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DQALLTLQ 8
           DQA++TL+
Sbjct: 194 DQAIITLR 201
>XP_006720309
          Length = 244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>XP_006720069
          Length = 155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>XP_006720068
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DQALLTLQ 8
          DQA+ TLQ
Sbjct: 70 DQAVATLQ 77
>NP_038466
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QALLTLQQ 9
           QALL +QQ
Sbjct: 461 QALLQIQQ 468
>NP_444295
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QALLTLQQ 9
           QALL +QQ
Sbjct: 433 QALLQIQQ 440
>NP_064516
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QALLTLQQ 9
           QALL +QQ
Sbjct: 467 QALLQIQQ 474
>NP_001800
          Length = 140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QALLTLQQ 9
          QALL LQ+
Sbjct: 89 QALLALQE 96
>NP_001032590
          Length = 942

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QALLTLQQ 9
           QALLTL +
Sbjct: 128 QALLTLDE 135
>NP_005104
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DQALLTLQQ 9
           +QAL TLQ+
Sbjct: 344 NQALQTLQE 352
>NP_001030598
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQALLTLQ 8
           DQA+ TLQ
Sbjct: 613 DQAVRTLQ 620
>NP_002004
          Length = 224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DQALLTLQQ 9
           D+ALLT+ +
Sbjct: 176 DEALLTMSK 184
>NP_001512
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQALLTLQ 8
           DQA+ TLQ
Sbjct: 613 DQAVRTLQ 620
>NP_001157101
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QALLTLQQ 9
           QALLTL++
Sbjct: 603 QALLTLRR 610
>XP_005264330
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQALLTLQ 8
           DQA+ TLQ
Sbjct: 624 DQAVRTLQ 631
>XP_005264329
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DQALLTLQ 8
           DQA+ TLQ
Sbjct: 652 DQAVRTLQ 659
>XP_005245404
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QALLTLQQ 9
           QALL +QQ
Sbjct: 467 QALLQIQQ 474
>XP_006710935
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QALLTLQQ 9
           QALLTL +
Sbjct: 195 QALLTLDE 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QALLTLQQ 9
           QALLTL +
Sbjct: 466 QALLTLDE 473
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.127    0.307 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 362,127
Number of extensions: 453
Number of successful extensions: 74
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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