Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1935
NP_671714                                                              18    1935
XP_006715890                                                           18    1935
XP_005250160                                                           18    1935
XP_005250159                                                           18    1935
NP_114426                                                              17    3301
NP_001138666                                                           17    4312
NP_689718                                                              17    4312
XP_006724036                                                           17    4312
XP_006724035                                                           17    4312
XP_006724034                                                           17    4312
XP_006724033                                                           17    4312
XP_006724032                                                           17    4312
XP_006724031                                                           17    4312
XP_005260983                                                           17    4312
XP_006724030                                                           17    4312
NP_001231509                                                           16    5631
NP_003487                                                              16    5631
NP_000611                                                              16    5631
NP_001191147                                                           16    5631
NP_001191142                                                           16    5631
NP_001191143                                                           16    5631
NP_004022                                                              16    5631
NP_004020                                                              16    5631
NP_001563                                                              16    5631
XP_006725202                                                           16    5631
XP_005252965                                                           16    5631
XP_006725201                                                           16    5631
XP_006725200                                                           16    5631
XP_006719491                                                           16    5631
XP_006719490                                                           16    5631
XP_006719489                                                           16    5631
XP_005268677                                                           16    5631
XP_006719281                                                           16    5631
XP_006719280                                                           16    5631
XP_005268675                                                           16    5631
XP_005268674                                                           16    5631
XP_005252966                                                           16    5631
XP_005252964                                                           16    5631
XP_005252963                                                           16    5631
NP_689705                                                              16    5631
NP_057332                                                              16    7355
NP_705618                                                              16    7355
NP_004289                                                              16    7355
NP_001265241                                                           16    7355
XP_005266305                                                           16    7355
XP_005266304                                                           16    7355
NP_001273758                                                           15    9605
NP_660202                                                              15    9605
NP_003815                                                              15    9605
>NP_005742
          Length = 3907

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLLQAIQQI 9
           DLLQA QQI
Sbjct: 262 DLLQAKQQI 270
>NP_671714
          Length = 3899

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLLQAIQQI 9
           DLLQA QQI
Sbjct: 262 DLLQAKQQI 270
>XP_006715890
          Length = 3860

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLLQAIQQI 9
           DLLQA QQI
Sbjct: 262 DLLQAKQQI 270
>XP_005250160
          Length = 3939

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLLQAIQQI 9
           DLLQA QQI
Sbjct: 262 DLLQAKQQI 270
>XP_005250159
          Length = 3952

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLLQAIQQI 9
           DLLQA QQI
Sbjct: 262 DLLQAKQQI 270
>NP_114426
          Length = 273

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DLLQAIQQ 8
           DLLQA+Q+
Sbjct: 96  DLLQAVQR 103
>NP_001138666
          Length = 69

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLQAIQQI 9
          +LQA+QQ+
Sbjct: 30 ILQAVQQV 37
>NP_689718
          Length = 670

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 240 DILQALQKL 248
>XP_006724036
          Length = 540

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 110 DILQALQKL 118
>XP_006724035
          Length = 540

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 110 DILQALQKL 118
>XP_006724034
          Length = 624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 240 DILQALQKL 248
>XP_006724033
          Length = 670

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 240 DILQALQKL 248
>XP_006724032
          Length = 670

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 240 DILQALQKL 248
>XP_006724031
          Length = 670

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 240 DILQALQKL 248
>XP_005260983
          Length = 670

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 240 DILQALQKL 248
>XP_006724030
          Length = 670

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+LQA+Q++
Sbjct: 240 DILQALQKL 248
>NP_001231509
          Length = 3859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LLQAIQQI 9
            LLQA QQI
Sbjct: 2933 LLQAAQQI 2940
>NP_003487
          Length = 3830

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LLQAIQQI 9
            LLQA QQI
Sbjct: 2915 LLQAAQQI 2922
>NP_000611
          Length = 1434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLLQAIQQI 9
            D+L+AIQ+I
Sbjct: 1362 DVLKAIQRI 1370
>NP_001191147
          Length = 1468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLLQAIQQI 9
            D+L+AIQ+I
Sbjct: 1396 DVLKAIQRI 1404
>NP_001191142
          Length = 1098

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLLQAIQQI 9
            D+L+AIQ+I
Sbjct: 1026 DVLKAIQRI 1034
>NP_001191143
          Length = 1098

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLLQAIQQI 9
            D+L+AIQ+I
Sbjct: 1026 DVLKAIQRI 1034
>NP_004022
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 196 LLQAVQQ 202
>NP_004020
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 183 LLQAVQQ 189
>NP_001563
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 183 LLQAVQQ 189
>XP_006725202
          Length = 487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 196 LLQAVQQ 202
>XP_005252965
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 182 LLQAVQQ 188
>XP_006725201
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 195 LLQAVQQ 201
>XP_006725200
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 196 LLQAVQQ 202
>XP_006719491
          Length = 1434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLLQAIQQI 9
            D+L+AIQ+I
Sbjct: 1362 DVLKAIQRI 1370
>XP_006719490
          Length = 1468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLLQAIQQI 9
            D+L+AIQ+I
Sbjct: 1396 DVLKAIQRI 1404
>XP_006719489
          Length = 1468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DLLQAIQQI 9
            D+L+AIQ+I
Sbjct: 1396 DVLKAIQRI 1404
>XP_005268677
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQAIQQI 9
           LLQ++QQI
Sbjct: 797 LLQSLQQI 804
>XP_006719281
          Length = 1004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQAIQQI 9
           LLQ++QQI
Sbjct: 797 LLQSLQQI 804
>XP_006719280
          Length = 1004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQAIQQI 9
           LLQ++QQI
Sbjct: 797 LLQSLQQI 804
>XP_005268675
          Length = 1004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQAIQQI 9
           LLQ++QQI
Sbjct: 797 LLQSLQQI 804
>XP_005268674
          Length = 1004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQAIQQI 9
           LLQ++QQI
Sbjct: 797 LLQSLQQI 804
>XP_005252966
          Length = 487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 196 LLQAVQQ 202
>XP_005252964
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 195 LLQAVQQ 201
>XP_005252963
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAIQQ 8
           LLQA+QQ
Sbjct: 196 LLQAVQQ 202
>NP_689705
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DLLQAIQQI 9
           D+L+A+Q+I
Sbjct: 610 DILEALQRI 618
>NP_057332
          Length = 1901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DLLQAIQQ 8
            DLLQA+ Q
Sbjct: 1869 DLLQAVLQ 1876
>NP_705618
          Length = 1391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LQAIQQI 9
           LQAIQQ+
Sbjct: 778 LQAIQQL 784
>NP_004289
          Length = 1332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LQAIQQI 9
           LQAIQQ+
Sbjct: 719 LQAIQQL 725
>NP_001265241
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LQAIQQI 9
           LQAIQQ+
Sbjct: 778 LQAIQQL 784
>XP_005266305
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DLLQAIQQ 8
            DLLQA+ Q
Sbjct: 1824 DLLQAVLQ 1831
>XP_005266304
          Length = 1873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DLLQAIQQ 8
            DLLQA+ Q
Sbjct: 1841 DLLQAVLQ 1848
>NP_001273758
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLLQAIQQI 9
           DLLQ  Q+I
Sbjct: 323 DLLQQAQEI 331
>NP_660202
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DLLQAIQQI 9
           DLLQ  Q+I
Sbjct: 323 DLLQQAQEI 331
>NP_003815
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLLQAIQQ 8
           DL+Q +QQ
Sbjct: 175 DLVQEVQQ 182
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.143    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 355,288
Number of extensions: 948
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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