Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              19     665
XP_005251512                                                           19     665
XP_006718921                                                           17    2528
NP_000768                                                              17    4312
NP_000756                                                              17    4312
NP_001243426                                                           17    4312
NP_055985                                                              17    4312
NP_001121678                                                           17    4312
NP_001121676                                                           17    4312
NP_001121677                                                           17    4312
NP_001189784                                                           17    4312
NP_059488                                                              17    4312
NP_001265850                                                           17    4312
NP_073731                                                              17    4312
NP_476436                                                              17    4312
NP_476437                                                              17    4312
XP_006716503                                                           17    4312
XP_006716502                                                           17    4312
XP_006716501                                                           17    4312
XP_006715923                                                           17    4312
NP_619639                                                              16    5631
NP_066008                                                              16    5631
NP_065087                                                              16    5631
NP_056532                                                              16    5631
NP_689647                                                              16    5631
XP_006718831                                                           16    5631
NP_001139192                                                           16    7355
NP_055918                                                              16    7355
NP_683692                                                              16    7355
NP_001091967                                                           16    7355
XP_006718977                                                           16    7355
XP_005248208                                                           16    7355
XP_005248207                                                           16    7355
XP_006714021                                                           16    7355
NP_001035037                                                           16    7355
NP_597711                                                              16    7355
NP_001091968                                                           16    7355
NP_001158192                                                           15    9605
NP_001018086                                                           15    9605
NP_001019265                                                           15    9605
NP_001018661                                                           15    9605
NP_001018085                                                           15    9605
NP_000167                                                              15    9605
NP_001018084                                                           15    9605
NP_001018087                                                           15    9605
NP_001191191                                                           15    9605
NP_001191194                                                           15    9605
NP_001191188                                                           15    9605
NP_001191189                                                           15    9605
NP_001191190                                                           15    9605
NP_001191192                                                           15    9605
NP_001191193                                                           15    9605
NP_001191187                                                           15    9605
NP_775099                                                              15    9605
NP_056472                                                              15    9605
NP_001157879                                                           15    9605
NP_061759                                                              15    9605
NP_061760                                                              15    9605
NP_061756                                                              15    9605
NP_061763                                                              15    9605
XP_006720235                                                           15    9605
XP_005268480                                                           15    9605
XP_005268479                                                           15    9605
XP_005268478                                                           15    9605
XP_005268477                                                           15    9605
XP_005268476                                                           15    9605
XP_006714033                                                           15    9605
NP_061993                                                              15    9605
NP_061762                                                              15    9605
NP_004560                                                              15    9605
>NP_004963
          Length = 1132

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLIVNESLG 9
           DLI NESLG
Sbjct: 544 DLIFNESLG 552
>XP_005251512
          Length = 1132

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DLIVNESLG 9
           DLI NESLG
Sbjct: 544 DLIFNESLG 552
>XP_006718921
          Length = 797

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DLIVNESLG 9
           DLI+N+S G
Sbjct: 781 DLILNDSFG 789
>NP_000768
          Length = 502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 357 DMVVNETL 364
>NP_000756
          Length = 503

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 357 DMVVNETL 364
>NP_001243426
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 357 DMVVNETL 364
>NP_055985
          Length = 871

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DLI NES+
Sbjct: 193 DLITNESI 200
>NP_001121678
          Length = 871

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DLI NES+
Sbjct: 193 DLITNESI 200
>NP_001121676
          Length = 871

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DLI NES+
Sbjct: 193 DLITNESI 200
>NP_001121677
          Length = 871

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DLI NES+
Sbjct: 193 DLITNESI 200
>NP_001189784
          Length = 502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 356 DMVVNETL 363
>NP_059488
          Length = 503

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 357 DMVVNETL 364
>NP_001265850
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 247 DMVVNETL 254
>NP_073731
          Length = 504

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 357 DMVVNETL 364
>NP_476436
          Length = 503

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 357 DMVVNETL 364
>NP_476437
          Length = 420

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 357 DMVVNETL 364
>XP_006716503
          Length = 1122

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DLI NES+
Sbjct: 193 DLITNESI 200
>XP_006716502
          Length = 1122

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DLI NES+
Sbjct: 193 DLITNESI 200
>XP_006716501
          Length = 1122

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DLI NES+
Sbjct: 193 DLITNESI 200
>XP_006715923
          Length = 322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D++VNE+L
Sbjct: 177 DMVVNETL 184
>NP_619639
          Length = 4074

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LIVNESLG 9
            L++NES+G
Sbjct: 3525 LLLNESIG 3532
>NP_066008
          Length = 776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLIVNESL 8
          DL++NE L
Sbjct: 83 DLLINEKL 90
>NP_065087
          Length = 604

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           DL++NE+L
Sbjct: 326 DLVLNETL 333
>NP_056532
          Length = 328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IVNESLG 9
           +VNESLG
Sbjct: 111 MVNESLG 117
>NP_689647
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLIVNESLG 9
           DL+ NE +G
Sbjct: 601 DLVKNEKMG 609
>XP_006718831
          Length = 418

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DLIVNESLG 9
           DL+ NE +G
Sbjct: 125 DLVKNEKMG 133
>NP_001139192
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DLIVNESLG 9
           +L+V +SLG
Sbjct: 204 ELVVRDSLG 212
>NP_055918
          Length = 1925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VNESLG 9
            VNESLG
Sbjct: 1236 VNESLG 1241
>NP_683692
          Length = 3051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LIVNESL 8
            L+VNESL
Sbjct: 2709 LLVNESL 2715
>NP_001091967
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DL+ NES+
Sbjct: 785 DLLANESM 792
>XP_006718977
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DLIVNESLG 9
          DL+ N SLG
Sbjct: 24 DLLGNHSLG 32
>XP_005248208
          Length = 3097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LIVNESL 8
            L+VNESL
Sbjct: 2709 LLVNESL 2715
>XP_005248207
          Length = 3098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LIVNESL 8
            L+VNESL
Sbjct: 2709 LLVNESL 2715
>XP_006714021
          Length = 3112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LIVNESL 8
            L+VNESL
Sbjct: 2709 LLVNESL 2715
>NP_001035037
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DL+ NES+
Sbjct: 840 DLLANESM 847
>NP_597711
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DL+ NES+
Sbjct: 779 DLLANESM 786
>NP_001091968
          Length = 1032

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DLIVNESL 8
           DL+ NES+
Sbjct: 724 DLLANESM 731
>NP_001158192
          Length = 111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DLIVNESLG 9
          +L+V +SLG
Sbjct: 84 ELVVKKSLG 92
>NP_001018086
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 626 DLIINE 631
>NP_001019265
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 627 DLIINE 632
>NP_001018661
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 626 DLIINE 631
>NP_001018085
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 626 DLIINE 631
>NP_000167
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 626 DLIINE 631
>NP_001018084
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 626 DLIINE 631
>NP_001018087
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 626 DLIINE 631
>NP_001191191
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 311 DLIINE 316
>NP_001191194
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 626 DLIINE 631
>NP_001191188
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 541 DLIINE 546
>NP_001191189
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 537 DLIINE 542
>NP_001191190
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 529 DLIINE 534
>NP_001191192
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 296 DLIINE 301
>NP_001191193
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 291 DLIINE 296
>NP_001191187
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 600 DLIINE 605
>NP_775099
          Length = 2595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LIVNESL 8
            L++NESL
Sbjct: 2205 LLINESL 2211
>NP_056472
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LIVNESL 8
            L++NESL
Sbjct: 1887 LLINESL 1893
>NP_001157879
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DLIVNESLG 9
           DL+ N++LG
Sbjct: 95  DLLWNQTLG 103
>NP_061759
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLIVNESL 8
          DL++NE L
Sbjct: 85 DLLLNEKL 92
>NP_061760
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLIVNESL 8
          DL++NE L
Sbjct: 83 DLLLNEKL 90
>NP_061756
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLIVNESL 8
          DL++NE L
Sbjct: 84 DLLLNEKL 91
>NP_061763
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLIVNESL 8
          DL++NE L
Sbjct: 83 DLLLNEKL 90
>XP_006720235
          Length = 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D+++NE++
Sbjct: 117 DIVINEAI 124
>XP_005268480
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 627 DLIINE 632
>XP_005268479
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 627 DLIINE 632
>XP_005268478
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 627 DLIINE 632
>XP_005268477
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 627 DLIINE 632
>XP_005268476
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DLIVNE 6
           DLI+NE
Sbjct: 627 DLIINE 632
>XP_006714033
          Length = 111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DLIVNESLG 9
          +L+V +SLG
Sbjct: 84 ELVVKKSLG 92
>NP_061993
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLIVNESL 8
          DL++NE L
Sbjct: 84 DLLLNEKL 91
>NP_061762
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  DLIVNESL 8
          DL++NE L
Sbjct: 82 DLLLNEKL 89
>NP_004560
          Length = 188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   DLIVNESL 8
           D+++NE++
Sbjct: 121 DIVINEAI 128
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.141    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 422,665
Number of extensions: 747
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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