Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000542                                                              20     509
NP_937799                                                              20     509
NP_061763                                                              18    1935
NP_001299                                                              17    2528
NP_003838                                                              17    4312
NP_001258501                                                           17    4312
NP_071445                                                              17    4312
XP_006721306                                                           17    4312
XP_006721305                                                           17    4312
XP_005256141                                                           17    4312
NP_054706                                                              16    5631
NP_003364                                                              16    5631
NP_006294                                                              16    5631
NP_061198                                                              16    5631
NP_078789                                                              16    5631
NP_006819                                                              16    5631
XP_006720670                                                           16    5631
XP_005270200                                                           16    5631
XP_005270199                                                           16    5631
XP_006715835                                                           16    5631
XP_005249905                                                           16    5631
XP_005249904                                                           16    5631
XP_006715385                                                           16    5631
XP_005265541                                                           16    5631
XP_006713398                                                           16    5631
XP_006713397                                                           16    5631
XP_006713396                                                           16    5631
NP_060835                                                              16    7355
NP_775289                                                              16    7355
NP_775287                                                              16    7355
NP_775285                                                              16    7355
NP_775286                                                              16    7355
NP_775284                                                              16    7355
NP_775283                                                              16    7355
NP_055406                                                              16    7355
NP_001030010                                                           16    7355
NP_001265268                                                           16    7355
NP_001265269                                                           16    7355
NP_055407                                                              16    7355
NP_001030009                                                           16    7355
XP_005269787                                                           16    7355
XP_005269786                                                           16    7355
XP_006717875                                                           16    7355
XP_006714924                                                           16    7355
XP_005263256                                                           16    7355
NP_001103447                                                           16    7355
NP_071397                                                              15    9605
NP_955533                                                              15    9605
NP_055845                                                              15    9605
NP_056359                                                              15    9605
NP_001020128                                                           15    9605
NP_001028676                                                           15    9605
NP_056214                                                              15    9605
NP_003322                                                              15    9605
NP_056075                                                              15    9605
XP_006722767                                                           15    9605
XP_005259889                                                           15    9605
XP_005273940                                                           15    9605
XP_005248150                                                           15    9605
XP_005248148                                                           15    9605
XP_005248147                                                           15    9605
XP_005248146                                                           15    9605
XP_005248145                                                           15    9605
XP_005248144                                                           15    9605
XP_005248143                                                           15    9605
XP_005248142                                                           15    9605
XP_005248141                                                           15    9605
XP_005248140                                                           15    9605
XP_005248139                                                           15    9605
XP_005244831                                                           15    9605
XP_005244830                                                           15    9605
XP_006710877                                                           15    9605
XP_005244829                                                           15    9605
>NP_000542
          Length = 213

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   DIVRSLYE 8
           DIVRSLYE
Sbjct: 179 DIVRSLYE 186
>NP_937799
          Length = 172

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   DIVRSLYE 8
           DIVRSLYE
Sbjct: 138 DIVRSLYE 145
>NP_061763
          Length = 793

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DIVRSLYEI 9
           D VRSLY++
Sbjct: 241 DFVRSLYKV 249
>NP_001299
          Length = 458

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  DIVRSLYEI 9
          D+VR+LY++
Sbjct: 30 DLVRTLYKV 38
>NP_003838
          Length = 247

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVRSLYEI 9
           +VR LYEI
Sbjct: 135 LVRDLYEI 142
>NP_001258501
          Length = 216

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVRSLYEI 9
           +VR LYEI
Sbjct: 104 LVRDLYEI 111
>NP_071445
          Length = 1040

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVRSLYEI 9
           ++RSLYE+
Sbjct: 742 LIRSLYEM 749
>XP_006721306
          Length = 793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVRSLYEI 9
           ++RSLYE+
Sbjct: 715 LIRSLYEM 722
>XP_006721305
          Length = 985

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVRSLYEI 9
           ++RSLYE+
Sbjct: 715 LIRSLYEM 722
>XP_005256141
          Length = 1013

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVRSLYEI 9
           ++RSLYE+
Sbjct: 715 LIRSLYEM 722
>NP_054706
          Length = 1134

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DIVRSLYEI 9
           DI+RSL EI
Sbjct: 430 DILRSLGEI 438
>NP_003364
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DIVRSLYEI 9
           DI+RSL EI
Sbjct: 430 DILRSLGEI 438
>NP_006294
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DIVRSLYEI 9
          DI++ LYE+
Sbjct: 61 DILKRLYEL 69
>NP_061198
          Length = 1742

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVRSLYEI 9
           +VRSLY++
Sbjct: 822 LVRSLYQL 829
>NP_078789
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DIVRSLYEI 9
           DIV  LYE+
Sbjct: 149 DIVGQLYEL 157
>NP_006819
          Length = 2202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IVRSLYEI 9
            IVR+L+EI
Sbjct: 1089 IVRALFEI 1096
>XP_006720670
          Length = 1712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVRSLYEI 9
           +VRSLY++
Sbjct: 822 LVRSLYQL 829
>XP_005270200
          Length = 1067

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DIVRSLYEI 9
           DI+RSL EI
Sbjct: 431 DILRSLGEI 439
>XP_005270199
          Length = 1135

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DIVRSLYEI 9
           DI+RSL EI
Sbjct: 431 DILRSLGEI 439
>XP_006715835
          Length = 276

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DIVRSLYEI 9
          DI++ LYE+
Sbjct: 17 DILKRLYEL 25
>XP_005249905
          Length = 280

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DIVRSLYEI 9
          DI++ LYE+
Sbjct: 21 DILKRLYEL 29
>XP_005249904
          Length = 313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DIVRSLYEI 9
          DI++ LYE+
Sbjct: 54 DILKRLYEL 62
>XP_006715385
          Length = 1866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVRSLYEI 9
           IVR+L+EI
Sbjct: 753 IVRALFEI 760
>XP_005265541
          Length = 1080

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DIVRSLYEI 9
           DIV  LYE+
Sbjct: 149 DIVGQLYEL 157
>XP_006713398
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DIVRSLYEI 9
           DIV  LYE+
Sbjct: 149 DIVGQLYEL 157
>XP_006713397
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DIVRSLYEI 9
           DIV  LYE+
Sbjct: 149 DIVGQLYEL 157
>XP_006713396
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DIVRSLYEI 9
           DIV  LYE+
Sbjct: 149 DIVGQLYEL 157
>NP_060835
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DIVRSLYE 8
           +IVR +YE
Sbjct: 218 EIVRKIYE 225
>NP_775289
          Length = 184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 117 DIMKSIYDM 125
>NP_775287
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 153 DIMKSIYDM 161
>NP_775285
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 160 DIMKSIYDM 168
>NP_775286
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 158 DIMKSIYDM 166
>NP_775284
          Length = 252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 185 DIMKSIYDM 193
>NP_775283
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 203 DIMKSIYDM 211
>NP_055406
          Length = 285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 218 DIMKSIYDM 226
>NP_001030010
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DIV+++Y++
Sbjct: 158 DIVKAIYDM 166
>NP_001265268
          Length = 241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DIV+++Y++
Sbjct: 174 DIVKAIYDM 182
>NP_001265269
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DIV+++Y++
Sbjct: 121 DIVKAIYDM 129
>NP_055407
          Length = 216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DIV+++Y++
Sbjct: 149 DIVKAIYDM 157
>NP_001030009
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DIV+++Y++
Sbjct: 160 DIVKAIYDM 168
>XP_005269787
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 153 DIMKSIYDM 161
>XP_005269786
          Length = 257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 185 DIMKSIYDM 193
>XP_006717875
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DI++S+Y++
Sbjct: 203 DIMKSIYDM 211
>XP_006714924
          Length = 241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   DIVRSLYEI 9
           DIV+++Y++
Sbjct: 174 DIVKAIYDM 182
>XP_005263256
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRSLYEI 9
           VRSLY++
Sbjct: 905 VRSLYQV 911
>NP_001103447
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRSLYEI 9
           VRSLY++
Sbjct: 905 VRSLYQV 911
>NP_071397
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DIVRSLYE 8
          D+V ++YE
Sbjct: 16 DVVNNMYE 23
>NP_955533
          Length = 1257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DIVRSLYE 8
          D+V ++YE
Sbjct: 16 DVVNNMYE 23
>NP_055845
          Length = 3013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1218 DSSRSIYEV 1226
>NP_056359
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DIVRSLY 7
           D+V+S+Y
Sbjct: 141 DVVKSMY 147
>NP_001020128
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DIVRSLYE 8
           D++R+ YE
Sbjct: 128 DVIRNKYE 135
>NP_001028676
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DIVRSLY 7
           D+V+S+Y
Sbjct: 141 DVVKSMY 147
>NP_056214
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DIVRSLYE 8
           D++R+ YE
Sbjct: 128 DVIRNKYE 135
>NP_003322
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DIVRSLY 7
           DI+R+LY
Sbjct: 949 DILRTLY 955
>NP_056075
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVRSLYE 8
           D+VRSL E
Sbjct: 853 DMVRSLLE 860
>XP_006722767
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVRSLYE 8
           D+VRSL E
Sbjct: 336 DMVRSLLE 343
>XP_005259889
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DIVRSLYE 8
           D+VRSL E
Sbjct: 821 DMVRSLLE 828
>XP_005273940
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DIVRSLYE 8
           D++R+ YE
Sbjct: 128 DVIRNKYE 135
>XP_005248150
          Length = 2044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DIVRSLYEI 9
           D  RS+YE+
Sbjct: 249 DSSRSIYEV 257
>XP_005248148
          Length = 3028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1233 DSSRSIYEV 1241
>XP_005248147
          Length = 3028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1233 DSSRSIYEV 1241
>XP_005248146
          Length = 3073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1325 DSSRSIYEV 1333
>XP_005248145
          Length = 3079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1284 DSSRSIYEV 1292
>XP_005248144
          Length = 3099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1310 DSSRSIYEV 1318
>XP_005248143
          Length = 3105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1310 DSSRSIYEV 1318
>XP_005248142
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1325 DSSRSIYEV 1333
>XP_005248141
          Length = 3119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1325 DSSRSIYEV 1333
>XP_005248140
          Length = 3119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1324 DSSRSIYEV 1332
>XP_005248139
          Length = 3120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DIVRSLYEI 9
            D  RS+YE+
Sbjct: 1325 DSSRSIYEV 1333
>XP_005244831
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DIVRSLYE 8
          D+V ++YE
Sbjct: 16 DVVNNMYE 23
>XP_005244830
          Length = 1258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DIVRSLYE 8
          D+V ++YE
Sbjct: 16 DVVNNMYE 23
>XP_006710877
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DIVRSLYE 8
          D+V ++YE
Sbjct: 16 DVVNNMYE 23
>XP_005244829
          Length = 1277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DIVRSLYE 8
          D+V ++YE
Sbjct: 16 DVVNNMYE 23
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.150    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 448,474
Number of extensions: 837
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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