Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1935
XP_006718908                                                           18    1935
XP_005271621                                                           18    1935
XP_006718907                                                           18    1935
XP_006718906                                                           18    1935
XP_005271619                                                           18    1935
XP_005271618                                                           18    1935
XP_005270208                                                           17    2528
XP_005270207                                                           17    2528
XP_005270206                                                           17    2528
NP_077302                                                              17    2528
NP_001159709                                                           16    5631
NP_612354                                                              16    5631
XP_006713882                                                           16    5631
XP_006713881                                                           16    5631
NP_079012                                                              16    5631
XP_006710433                                                           16    7355
XP_006710432                                                           16    7355
XP_006710431                                                           16    7355
XP_006710430                                                           16    7355
XP_006710429                                                           16    7355
NP_001159611                                                           15    9605
NP_060045                                                              15    9605
NP_997205                                                              15    9605
NP_001007596                                                           15    9605
NP_000022                                                              15    9605
NP_060069                                                              15    9605
XP_005256627                                                           15    9605
XP_006721558                                                           15    9605
XP_006721557                                                           15    9605
XP_006721556                                                           15    9605
XP_005256626                                                           15    9605
XP_006719553                                                           15    9605
XP_006719552                                                           15    9605
XP_006719551                                                           15    9605
XP_006719550                                                           15    9605
XP_006719549                                                           15    9605
XP_006719548                                                           15    9605
XP_006719547                                                           15    9605
XP_006719546                                                           15    9605
XP_006719545                                                           15    9605
XP_006719544                                                           15    9605
XP_006719543                                                           15    9605
XP_006719542                                                           15    9605
XP_006719541                                                           15    9605
XP_006719540                                                           15    9605
XP_005251856                                                           15    9605
NP_005313                                                              15    9605
>NP_000042
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGLALRALK 9
            D LALRALK
Sbjct: 2448 DELALRALK 2456
>XP_006718908
          Length = 1708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGLALRALK 9
            D LALRALK
Sbjct: 1100 DELALRALK 1108
>XP_005271621
          Length = 2708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGLALRALK 9
            D LALRALK
Sbjct: 2100 DELALRALK 2108
>XP_006718907
          Length = 3050

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGLALRALK 9
            D LALRALK
Sbjct: 2442 DELALRALK 2450
>XP_006718906
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGLALRALK 9
            D LALRALK
Sbjct: 2448 DELALRALK 2456
>XP_005271619
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGLALRALK 9
            D LALRALK
Sbjct: 2448 DELALRALK 2456
>XP_005271618
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DGLALRALK 9
            D LALRALK
Sbjct: 2448 DELALRALK 2456
>XP_005270208
          Length = 300

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DGLALRAL 8
           DGLALR L
Sbjct: 154 DGLALRGL 161
>XP_005270207
          Length = 300

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DGLALRAL 8
           DGLALR L
Sbjct: 154 DGLALRGL 161
>XP_005270206
          Length = 387

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DGLALRAL 8
           DGLALR L
Sbjct: 241 DGLALRGL 248
>NP_077302
          Length = 300

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DGLALRAL 8
           DGLALR L
Sbjct: 154 DGLALRGL 161
>NP_001159709
          Length = 484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGLALRALK 9
           D LALRAL+
Sbjct: 322 DQLALRALE 330
>NP_612354
          Length = 1242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DGLALRALK 9
            DGL L ALK
Sbjct: 1205 DGLDLAALK 1213
>XP_006713882
          Length = 1242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    DGLALRALK 9
            DGL L ALK
Sbjct: 1205 DGLDLAALK 1213
>XP_006713881
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DGL L ALK
Sbjct: 987 DGLDLAALK 995
>NP_079012
          Length = 484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DGLALRALK 9
           D LALRAL+
Sbjct: 322 DQLALRALE 330
>XP_006710433
          Length = 1169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGLALRA 7
           DGL LRA
Sbjct: 107 DGLGLRA 113
>XP_006710432
          Length = 1202

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGLALRA 7
           DGL LRA
Sbjct: 107 DGLGLRA 113
>XP_006710431
          Length = 1205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGLALRA 7
           DGL LRA
Sbjct: 107 DGLGLRA 113
>XP_006710430
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGLALRA 7
           DGL LRA
Sbjct: 107 DGLGLRA 113
>XP_006710429
          Length = 1238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DGLALRA 7
           DGL LRA
Sbjct: 107 DGLGLRA 113
>NP_001159611
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DGL  +ALK
Sbjct: 277 DGLLSKALK 285
>NP_060045
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALRA 7
           DGLA+R+
Sbjct: 705 DGLAIRS 711
>NP_997205
          Length = 369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DGL  RAL+
Sbjct: 186 DGLLSRALR 194
>NP_001007596
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DGL  RAL+
Sbjct: 181 DGLLSRALR 189
>NP_000022
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLALRAL 8
           GLALRA+
Sbjct: 232 GLALRAV 238
>NP_060069
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 324 DGFSLPALK 332
>XP_005256627
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALRA 7
           DGLA+R+
Sbjct: 705 DGLAIRS 711
>XP_006721558
          Length = 909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALRA 7
           DGLA+R+
Sbjct: 705 DGLAIRS 711
>XP_006721557
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALRA 7
           DGLA+R+
Sbjct: 705 DGLAIRS 711
>XP_006721556
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALRA 7
           DGLA+R+
Sbjct: 705 DGLAIRS 711
>XP_005256626
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALRA 7
           DGLA+R+
Sbjct: 674 DGLAIRS 680
>XP_006719553
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 276 DGFSLPALK 284
>XP_006719552
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 324 DGFSLPALK 332
>XP_006719551
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 328 DGFSLPALK 336
>XP_006719550
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 328 DGFSLPALK 336
>XP_006719549
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 176 DGFSLPALK 184
>XP_006719548
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 180 DGFSLPALK 188
>XP_006719547
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 180 DGFSLPALK 188
>XP_006719546
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 180 DGFSLPALK 188
>XP_006719545
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 250 DGFSLPALK 258
>XP_006719544
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 250 DGFSLPALK 258
>XP_006719543
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 280 DGFSLPALK 288
>XP_006719542
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 280 DGFSLPALK 288
>XP_006719541
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 298 DGFSLPALK 306
>XP_006719540
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DGLALRALK 9
           DG +L ALK
Sbjct: 328 DGFSLPALK 336
>XP_005251856
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLALRAL 8
           GLALRA+
Sbjct: 261 GLALRAV 267
>NP_005313
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DGLALRALK 9
          +GL+L ALK
Sbjct: 58 NGLSLAALK 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.144    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 303,428
Number of extensions: 362
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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