Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000206                                                              17    4312
XP_006722808                                                           17    4312
XP_005259953                                                           17    4312
NP_003430                                                              16    5631
XP_005250622                                                           16    5631
XP_006716175                                                           16    5631
NP_001131136                                                           16    7355
NP_057322                                                              16    7355
NP_061759                                                              16    7355
XP_005253960                                                           16    7355
XP_006719513                                                           16    7355
XP_006713927                                                           16    7355
NP_660334                                                              16    7355
NP_056207                                                              15    9605
>NP_000206
          Length = 1124

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGLALIRV 8
           DGL L+RV
Sbjct: 266 DGLGLLRV 273
>XP_006722808
          Length = 1124

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGLALIRV 8
           DGL L+RV
Sbjct: 266 DGLGLLRV 273
>XP_005259953
          Length = 1167

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DGLALIRV 8
           DGL L+RV
Sbjct: 309 DGLGLLRV 316
>NP_003430
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DGLALIRVE 9
          DG+ +++VE
Sbjct: 21 DGIVIVKVE 29
>XP_005250622
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DGLALIRVE 9
          DG+ +++VE
Sbjct: 21 DGIVIVKVE 29
>XP_006716175
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DGLALIRVE 9
          DG+ +++VE
Sbjct: 21 DGIVIVKVE 29
>NP_001131136
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALIR 7
           DG+AL+R
Sbjct: 494 DGIALLR 500
>NP_057322
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALIR 7
           DG+AL+R
Sbjct: 494 DGIALLR 500
>NP_061759
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GLALIRVE 9
           G AL+R+E
Sbjct: 226 GTALVRIE 233
>XP_005253960
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALIR 7
           DG+AL+R
Sbjct: 273 DGIALLR 279
>XP_006719513
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALIR 7
           DG+AL+R
Sbjct: 447 DGIALLR 453
>XP_006713927
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALIR 7
           DG+A+IR
Sbjct: 707 DGMAMIR 713
>NP_660334
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DGLALIR 7
           DG+A+IR
Sbjct: 707 DGMAMIR 713
>NP_056207
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DGLALIRV 8
           DGLAL+ +
Sbjct: 181 DGLALVLI 188
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.152    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 369,963
Number of extensions: 630
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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