Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           20     390
NP_000240                                                              20     390
XP_005265218                                                           20     390
NP_056999                                                              18    1482
NP_853629                                                              18    1482
NP_001121185                                                           18    1482
NP_001061                                                              18    1935
NP_056445                                                              18    1935
XP_005257280                                                           18    1935
XP_005257279                                                           18    1935
XP_006712474                                                           18    1935
NP_057521                                                              18    1935
XP_005248380                                                           17    4312
XP_005248379                                                           17    4312
XP_005248378                                                           17    4312
NP_060610                                                              17    4312
NP_001243143                                                           16    5631
NP_689509                                                              16    5631
NP_001243142                                                           16    5631
NP_000693                                                              16    5631
NP_001153705                                                           16    5631
NP_000692                                                              16    5631
NP_001153706                                                           16    5631
NP_055746                                                              16    5631
XP_005259010                                                           16    5631
XP_005258727                                                           16    5631
XP_005258726                                                           16    5631
XP_006711403                                                           16    5631
XP_006710718                                                           16    5631
NP_653300                                                              16    5631
NP_001077430                                                           16    7355
NP_775907                                                              16    7355
NP_000695                                                              16    7355
XP_005258866                                                           16    7355
NP_525128                                                              15    9605
NP_001164100                                                           15    9605
NP_001554                                                              15    9605
NP_001269297                                                           15    9605
NP_065971                                                              15    9605
NP_001276988                                                           15    9605
NP_001025181                                                           15    9605
NP_001154945                                                           15    9605
NP_000685                                                              15    9605
NP_055592                                                              15    9605
NP_055073                                                              15    9605
NP_001180438                                                           15    9605
NP_002724                                                              15    9605
NP_060205                                                              15    9605
NP_001026786                                                           15    9605
NP_001193639                                                           15    9605
XP_006723744                                                           15    9605
XP_005260304                                                           15    9605
XP_005269077                                                           15    9605
XP_006719563                                                           15    9605
XP_006719562                                                           15    9605
XP_005269076                                                           15    9605
XP_005253197                                                           15    9605
XP_005264473                                                           15    9605
XP_005273417                                                           15    9605
NP_001193638                                                           15    9605
NP_001035792                                                           15    9605
NP_000686                                                              15    9605
>NP_001245200
          Length = 687

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  DETVLNRIA 9
          DETV+NRIA
Sbjct: 12 DETVVNRIA 20
>NP_000240
          Length = 756

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  DETVLNRIA 9
          DETV+NRIA
Sbjct: 12 DETVVNRIA 20
>XP_005265218
          Length = 687

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  DETVLNRIA 9
          DETV+NRIA
Sbjct: 12 DETVVNRIA 20
>NP_056999
          Length = 558

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  DETVLNRI 8
          DET LNRI
Sbjct: 49 DETALNRI 56
>NP_853629
          Length = 553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  DETVLNRI 8
          DET LNRI
Sbjct: 49 DETALNRI 56
>NP_001121185
          Length = 553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  DETVLNRI 8
          DET LNRI
Sbjct: 49 DETALNRI 56
>NP_001061
          Length = 451

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D T LNRIA
Sbjct: 206 DNTALNRIA 214
>NP_056445
          Length = 807

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   DETVLNRI 8
           DET+LNR+
Sbjct: 121 DETLLNRL 128
>XP_005257280
          Length = 298

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DETVLNRIA 9
          D T LNRIA
Sbjct: 53 DNTALNRIA 61
>XP_005257279
          Length = 460

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D T LNRIA
Sbjct: 215 DNTALNRIA 223
>XP_006712474
          Length = 689

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  DETVLNRI 8
          DET+LNR+
Sbjct: 5  DETLLNRL 12
>NP_057521
          Length = 451

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D T LNRIA
Sbjct: 206 DNTALNRIA 214
>XP_005248380
          Length = 458

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  DETVLNRIA 9
          DE VLN IA
Sbjct: 5  DEAVLNLIA 13
>XP_005248379
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           DE VLN IA
Sbjct: 144 DEAVLNLIA 152
>XP_005248378
          Length = 647

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           DE VLN IA
Sbjct: 194 DEAVLNLIA 202
>NP_060610
          Length = 647

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           DE VLN IA
Sbjct: 194 DEAVLNLIA 202
>NP_001243143
          Length = 1026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 266 DRTVMGRIA 274
>NP_689509
          Length = 1013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 253 DRTVMGRIA 261
>NP_001243142
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 264 DRTVMGRIA 272
>NP_000693
          Length = 1020

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 261 DRTVMGRIA 269
>NP_001153705
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 263 DRTVMGRIA 271
>NP_000692
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 263 DRTVMGRIA 271
>NP_001153706
          Length = 992

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 232 DRTVMGRIA 240
>NP_055746
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DETVLNRI 8
           DE++LNR+
Sbjct: 99  DESLLNRL 106
>XP_005259010
          Length = 1261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 253 DRTVMGRIA 261
>XP_005258727
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DETVLNRI 8
           DE++LNR+
Sbjct: 99  DESLLNRL 106
>XP_005258726
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DETVLNRI 8
           DE++LNR+
Sbjct: 99  DESLLNRL 106
>XP_006711403
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 203 DSTVMGRIA 211
>XP_006710718
          Length = 992

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 232 DRTVMGRIA 240
>NP_653300
          Length = 1029

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D TV+ RIA
Sbjct: 271 DSTVMGRIA 279
>NP_001077430
          Length = 1523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DETVLNRIA 9
          +ETV NR++
Sbjct: 53 EETVQNRVS 61
>NP_775907
          Length = 1518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DETVLNRIA 9
          +ETV NR++
Sbjct: 53 EETVQNRVS 61
>NP_000695
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DETVLNRIA 9
           D T++ RIA
Sbjct: 274 DRTIIGRIA 282
>XP_005258866
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DETVLNRIA 9
          +ETV NR++
Sbjct: 53 EETVQNRVS 61
>NP_525128
          Length = 72

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DETVLNR 7
          DE++LNR
Sbjct: 63 DESLLNR 69
>NP_001164100
          Length = 2581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    ETVLNRI 8
            ETV NR+
Sbjct: 2399 ETVFNRV 2405
>NP_001554
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DETVLNRI 8
           D+T+LN I
Sbjct: 202 DDTLLNEI 209
>NP_001269297
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DETVLNRI 8
           D+T+LN I
Sbjct: 124 DDTLLNEI 131
>NP_065971
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    ETVLNRI 8
            ETV NR+
Sbjct: 2120 ETVFNRV 2126
>NP_001276988
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ETVLNRIA 9
          +TV NR+A
Sbjct: 30 QTVANRVA 37
>NP_001025181
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ETVLNRIA 9
           +TV NR+A
Sbjct: 189 QTVANRVA 196
>NP_001154945
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ETVLNRIA 9
           +TV NR+A
Sbjct: 226 QTVANRVA 233
>NP_000685
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ETVLNRIA 9
           +TV NR+A
Sbjct: 226 QTVANRVA 233
>NP_055592
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           +TVLNR+
Sbjct: 279 DTVLNRL 285
>NP_055073
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DETVLNRI 8
           DE VLN I
Sbjct: 119 DEAVLNMI 126
>NP_001180438
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DETVLNRI 8
           D+T+LN I
Sbjct: 269 DDTILNDI 276
>NP_002724
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           ET++NR+
Sbjct: 286 ETIINRL 292
>NP_060205
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DETVLNRI 8
           D+T+LN I
Sbjct: 319 DDTILNDI 326
>NP_001026786
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ETVLNRIA 9
           +TV NR+A
Sbjct: 145 QTVANRVA 152
>NP_001193639
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           ET++NR+
Sbjct: 254 ETIINRL 260
>XP_006723744
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DETVLNRI 8
           DE VLN I
Sbjct: 119 DEAVLNMI 126
>XP_005260304
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DETVLNRI 8
           DE VLN I
Sbjct: 119 DEAVLNMI 126
>XP_005269077
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           ET++NR+
Sbjct: 202 ETIINRL 208
>XP_006719563
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           ET++NR+
Sbjct: 235 ETIINRL 241
>XP_006719562
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           ET++NR+
Sbjct: 254 ETIINRL 260
>XP_005269076
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           ET++NR+
Sbjct: 323 ETIINRL 329
>XP_005253197
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DETVLNR 7
           DET LNR
Sbjct: 699 DETNLNR 705
>XP_005264473
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DETVLNRI 8
           D+T+LN I
Sbjct: 319 DDTILNDI 326
>XP_005273417
          Length = 1487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           +TVLNR+
Sbjct: 279 DTVLNRL 285
>NP_001193638
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ETVLNRI 8
           ET++NR+
Sbjct: 295 ETIINRL 301
>NP_001035792
          Length = 72

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DETVLNR 7
          DE++LNR
Sbjct: 63 DESLLNR 69
>NP_000686
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ETVLNRIA 9
           +TV NR+A
Sbjct: 145 QTVANRVA 152
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.132    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 364,826
Number of extensions: 738
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package