Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005581                                                              18    1135
NP_005582                                                              18    1135
XP_006718905                                                           18    1135
XP_005274064                                                           18    1135
NP_208325                                                              18    1482
XP_005251379                                                           18    1482
XP_005251378                                                           18    1482
XP_005251377                                                           18    1482
XP_005251376                                                           18    1482
XP_005251375                                                           18    1482
XP_005251374                                                           18    1482
NP_085134                                                              17    3301
NP_001164641                                                           17    3301
NP_001186020                                                           17    3301
NP_001186014                                                           17    3301
NP_775804                                                              17    3301
NP_001186018                                                           17    3301
XP_005244992                                                           17    3301
XP_006711258                                                           17    3301
XP_005244991                                                           17    3301
NP_443142                                                              17    4312
NP_001268432                                                           17    4312
NP_001165783                                                           17    4312
NP_002661                                                              17    4312
NP_001138791                                                           17    4312
XP_006713725                                                           17    4312
XP_006713724                                                           17    4312
XP_006713723                                                           17    4312
NP_001020272                                                           16    5631
NP_001020271                                                           16    5631
NP_060695                                                              16    5631
NP_002262                                                              16    5631
XP_005266756                                                           16    5631
XP_005254110                                                           16    5631
XP_005254109                                                           16    5631
XP_005254106                                                           16    5631
XP_005251560                                                           16    5631
NP_997320                                                              16    7355
NP_078976                                                              16    7355
NP_078832                                                              16    7355
NP_079229                                                              16    7355
NP_004740                                                              16    7355
NP_112162                                                              16    7355
NP_954573                                                              16    7355
NP_619636                                                              16    7355
NP_001248763                                                           16    7355
XP_005253995                                                           16    7355
XP_006719669                                                           16    7355
XP_005253612                                                           16    7355
XP_005271723                                                           16    7355
XP_005271722                                                           16    7355
XP_005274106                                                           16    7355
XP_005274105                                                           16    7355
NP_001071639                                                           16    7355
NP_056969                                                              16    7355
NP_060599                                                              15    9605
NP_001138633                                                           15    9605
XP_006723847                                                           15    9605
XP_005257557                                                           15    9605
XP_005248304                                                           15    9605
NP_004966                                                              15    9605
>NP_005581
          Length = 680

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  DDNTFKSLV 9
          D+NTFK LV
Sbjct: 9  DENTFKILV 17
>NP_005582
          Length = 708

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  DDNTFKSLV 9
          D+NTFK LV
Sbjct: 9  DENTFKILV 17
>XP_006718905
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  DDNTFKSLV 9
          D+NTFK LV
Sbjct: 9  DENTFKILV 17
>XP_005274064
          Length = 708

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  DDNTFKSLV 9
          D+NTFK LV
Sbjct: 9  DENTFKILV 17
>NP_208325
          Length = 1032

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DDNTFKSLV 9
           +DNT++SLV
Sbjct: 419 EDNTYQSLV 427
>XP_005251379
          Length = 653

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  DDNTFKSLV 9
          +DNT++SLV
Sbjct: 40 EDNTYQSLV 48
>XP_005251378
          Length = 659

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  DDNTFKSLV 9
          +DNT++SLV
Sbjct: 46 EDNTYQSLV 54
>XP_005251377
          Length = 733

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DDNTFKSLV 9
           +DNT++SLV
Sbjct: 120 EDNTYQSLV 128
>XP_005251376
          Length = 733

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DDNTFKSLV 9
           +DNT++SLV
Sbjct: 120 EDNTYQSLV 128
>XP_005251375
          Length = 939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DDNTFKSLV 9
           +DNT++SLV
Sbjct: 326 EDNTYQSLV 334
>XP_005251374
          Length = 970

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   DDNTFKSLV 9
           +DNT++SLV
Sbjct: 419 EDNTYQSLV 427
>NP_085134
          Length = 299

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DDNTFKSLV 9
          D N++KSLV
Sbjct: 49 DPNSYKSLV 57
>NP_001164641
          Length = 298

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DDNTFKSLV 9
          D N++KSLV
Sbjct: 49 DPNSYKSLV 57
>NP_001186020
          Length = 981

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +NTFKS++
Sbjct: 279 ENTFKSVI 286
>NP_001186014
          Length = 1035

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +NTFKS++
Sbjct: 279 ENTFKSVI 286
>NP_775804
          Length = 981

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +NTFKS++
Sbjct: 279 ENTFKSVI 286
>NP_001186018
          Length = 1035

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +NTFKS++
Sbjct: 279 ENTFKSVI 286
>XP_005244992
          Length = 1035

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +NTFKS++
Sbjct: 279 ENTFKSVI 286
>XP_006711258
          Length = 1035

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +NTFKS++
Sbjct: 279 ENTFKSVI 286
>XP_005244991
          Length = 1035

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +NTFKS++
Sbjct: 279 ENTFKSVI 286
>NP_443142
          Length = 696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DDNTFKSLV 9
           ++NTFK+L+
Sbjct: 415 ENNTFKNLL 423
>NP_001268432
          Length = 696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DDNTFKSLV 9
           ++NTFK+L+
Sbjct: 415 ENNTFKNLL 423
>NP_001165783
          Length = 629

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD+ FKSL
Sbjct: 152 DDSLFKSL 159
>NP_002661
          Length = 629

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD+ FKSL
Sbjct: 152 DDSLFKSL 159
>NP_001138791
          Length = 629

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD+ FKSL
Sbjct: 152 DDSLFKSL 159
>XP_006713725
          Length = 629

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD+ FKSL
Sbjct: 152 DDSLFKSL 159
>XP_006713724
          Length = 629

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD+ FKSL
Sbjct: 152 DDSLFKSL 159
>XP_006713723
          Length = 629

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD+ FKSL
Sbjct: 152 DDSLFKSL 159
>NP_001020272
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DDNTFK 6
           +DNTFK
Sbjct: 103 EDNTFK 108
>NP_001020271
          Length = 197

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DDNTFK 6
           +DNTFK
Sbjct: 103 EDNTFK 108
>NP_060695
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NTFKSL 8
           NTFKSL
Sbjct: 385 NTFKSL 390
>NP_002262
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           DD+  KSLV
Sbjct: 251 DDSVLKSLV 259
>XP_005266756
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DDNTFK 6
           +DNTFK
Sbjct: 103 EDNTFK 108
>XP_005254110
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           DD+  KSLV
Sbjct: 251 DDSVLKSLV 259
>XP_005254109
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           DD+  KSLV
Sbjct: 251 DDSVLKSLV 259
>XP_005254106
          Length = 1115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           DD+  KSLV
Sbjct: 251 DDSVLKSLV 259
>XP_005251560
          Length = 462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NTFKSL 8
           NTFKSL
Sbjct: 334 NTFKSL 339
>NP_997320
          Length = 4471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1    DDNTF 5
            DDNTF
Sbjct: 1438 DDNTF 1442
>NP_078976
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           D NTF+ +V
Sbjct: 235 DTNTFRGVV 243
>NP_078832
          Length = 351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD TF++L
Sbjct: 254 DDTTFQAL 261
>NP_079229
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +N+FKSL+
Sbjct: 802 ENSFKSLL 809
>NP_004740
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           D NTF+ L+
Sbjct: 447 DQNTFQKLL 455
>NP_112162
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           D NTF+ L+
Sbjct: 337 DQNTFQKLL 345
>NP_954573
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           D NTF+ L+
Sbjct: 337 DQNTFQKLL 345
>NP_619636
          Length = 760

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   DDNTF 5
           DDNTF
Sbjct: 307 DDNTF 311
>NP_001248763
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DDNTFKSLV 9
           D NTF+ L+
Sbjct: 458 DQNTFQKLL 466
>XP_005253995
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +N+FKSL+
Sbjct: 666 ENSFKSLL 673
>XP_006719669
          Length = 944

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DNTFKSLV 9
           +N+FKSL+
Sbjct: 774 ENSFKSLL 781
>XP_005253612
          Length = 4589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1    DDNTF 5
            DDNTF
Sbjct: 1556 DDNTF 1560
>XP_005271723
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD TF++L
Sbjct: 254 DDTTFQAL 261
>XP_005271722
          Length = 350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           DD TF++L
Sbjct: 254 DDTTFQAL 261
>XP_005274106
          Length = 1685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           D+NT KSL
Sbjct: 108 DENTRKSL 115
>XP_005274105
          Length = 1686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           D+NT KSL
Sbjct: 108 DENTRKSL 115
>NP_001071639
          Length = 113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  DDNTFKS 7
          D+NTF S
Sbjct: 54 DENTFSS 60
>NP_056969
          Length = 1555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DDNTFKSL 8
           D+NT KSL
Sbjct: 108 DENTRKSL 115
>NP_060599
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DDNTFKSLV 9
           D N F SLV
Sbjct: 122 DSNPFASLV 130
>NP_001138633
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TFKSLV 9
           TFKSLV
Sbjct: 140 TFKSLV 145
>XP_006723847
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DDNTFKSL 8
           DD  FKS+
Sbjct: 357 DDTKFKSI 364
>XP_005257557
          Length = 181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  DDNTFKSLV 9
          D N F SLV
Sbjct: 42 DSNPFASLV 50
>XP_005248304
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TFKSLV 9
           TFKSLV
Sbjct: 246 TFKSLV 251
>NP_004966
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DDNTFKSL 8
           DD  FKS+
Sbjct: 357 DDTKFKSI 364
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.132    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 594,214
Number of extensions: 1268
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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