Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_060941                                                              18    1935
NP_065883                                                              17    3301
XP_006717971                                                           17    3301
XP_005245423                                                           17    3301
XP_005245425                                                           17    3301
NP_004124                                                              16    7355
NP_079408                                                              16    7355
NP_056197                                                              16    7355
NP_653226                                                              16    7355
NP_075266                                                              16    7355
NP_004449                                                              16    7355
NP_055445                                                              16    7355
NP_001138587                                                           16    7355
XP_006724698                                                           16    7355
XP_005262167                                                           16    7355
XP_005262166                                                           16    7355
XP_005262165                                                           16    7355
XP_006722562                                                           16    7355
XP_006722561                                                           16    7355
XP_006722560                                                           16    7355
XP_006722559                                                           16    7355
XP_005266781                                                           16    7355
XP_006722558                                                           16    7355
XP_005266780                                                           16    7355
XP_005266779                                                           16    7355
XP_005255053                                                           16    7355
XP_005267560                                                           16    7355
XP_005267559                                                           16    7355
XP_006716509                                                           16    7355
XP_006714089                                                           16    7355
XP_006714088                                                           16    7355
XP_005262715                                                           16    7355
XP_006711799                                                           16    7355
NP_060651                                                              16    7355
NP_000262                                                              15    9605
NP_003089                                                              15    9605
NP_036385                                                              15    9605
NP_001139406                                                           15    9605
NP_001139405                                                           15    9605
NP_570129                                                              15    9605
NP_079384                                                              15    9605
XP_005260574                                                           15    9605
XP_006722542                                                           15    9605
XP_005258336                                                           15    9605
XP_005258335                                                           15    9605
XP_005258334                                                           15    9605
XP_006721018                                                           15    9605
XP_006712321                                                           15    9605
>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1682 SKRLVFID 1689
>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1703 SKRLVFID 1710
>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1713 SKRLVFID 1720
>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1713 SKRLVFID 1720
>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1682 SKRLVFID 1689
>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1692 SKRLVFID 1699
>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1713 SKRLVFID 1720
>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1700 SKRLVFID 1707
>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1703 SKRLVFID 1710
>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SKRLVFID 9
            SKRLVFID
Sbjct: 1713 SKRLVFID 1720
>NP_060941
          Length = 426

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           C KR V+ID
Sbjct: 131 CEKRSVYID 139
>NP_065883
          Length = 1237

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CSKRLVFID 9
           C++RLVF +
Sbjct: 566 CARRLVFFN 574
>XP_006717971
          Length = 559

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           CS RLVF
Sbjct: 546 CSSRLVF 552
>XP_005245423
          Length = 1246

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CSKRLVFID 9
           C++RLVF +
Sbjct: 575 CARRLVFFN 583
>XP_005245425
          Length = 1299

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CSKRLVFID 9
           C++RLVF +
Sbjct: 628 CARRLVFFN 636
>NP_004124
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CSKRLVFID 9
           C K +VF D
Sbjct: 276 CLKAIVFFD 284
>NP_079408
          Length = 1342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   RLVFID 9
           RLVFID
Sbjct: 528 RLVFID 533
>NP_056197
          Length = 2610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CSKRLVFID 9
          C++R+V +D
Sbjct: 88 CTRRIVGVD 96
>NP_653226
          Length = 1081

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CSKRLVFI 8
           C +RL+F+
Sbjct: 550 CLRRLIFL 557
>NP_075266
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           C K ++++D
Sbjct: 221 CVKHIIYVD 229
>NP_004449
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           C K ++++D
Sbjct: 180 CVKHIIYVD 188
>NP_055445
          Length = 1267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           CSK L+F +
Sbjct: 620 CSKTLLFFN 628
>NP_001138587
          Length = 358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CSKRLVFID 9
           C KR+ F D
Sbjct: 128 CKKRVQFAD 136
>XP_006724698
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           C K ++++D
Sbjct: 180 CVKHIIYVD 188
>XP_005262167
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           C K ++++D
Sbjct: 180 CVKHIIYVD 188
>XP_005262166
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           C K ++++D
Sbjct: 221 CVKHIIYVD 229
>XP_005262165
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           C K ++++D
Sbjct: 221 CVKHIIYVD 229
>XP_006722562
          Length = 1060

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_006722561
          Length = 1094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_006722560
          Length = 1295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_006722559
          Length = 1297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_005266781
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_006722558
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_005266780
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_005266779
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>XP_005255053
          Length = 1267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSKRLVFID 9
           CSK L+F +
Sbjct: 620 CSKTLLFFN 628
>XP_005267560
          Length = 2563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CSKRLVFID 9
          C++R+V +D
Sbjct: 88 CTRRIVGVD 96
>XP_005267559
          Length = 2610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  CSKRLVFID 9
          C++R+V +D
Sbjct: 88 CTRRIVGVD 96
>XP_006716509
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CSKRLVFID 9
           C K +VF D
Sbjct: 163 CLKAIVFFD 171
>XP_006714089
          Length = 1281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   RLVFID 9
           RLVFID
Sbjct: 528 RLVFID 533
>XP_006714088
          Length = 1283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   RLVFID 9
           RLVFID
Sbjct: 469 RLVFID 474
>XP_005262715
          Length = 1320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   RLVFID 9
           RLVFID
Sbjct: 506 RLVFID 511
>XP_006711799
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CSKRLVFI 8
           C +RL+F+
Sbjct: 560 CLRRLIFL 567
>NP_060651
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSKRLVF 7
           C+K LVF
Sbjct: 649 CTKNLVF 655
>NP_000262
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSKRLVFI 8
           CS  LVF+
Sbjct: 364 CSSGLVFV 371
>NP_003089
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSKRLVFI 8
           C K +VFI
Sbjct: 482 CPKTIVFI 489
>NP_036385
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SKRLVFID 9
          +KRL F+D
Sbjct: 83 AKRLSFVD 90
>NP_001139406
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SKRLVFID 9
          +KRL F+D
Sbjct: 27 AKRLSFVD 34
>NP_001139405
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SKRLVFID 9
          +KRL F+D
Sbjct: 77 AKRLSFVD 84
>NP_570129
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RLVFID 9
           RL+FID
Sbjct: 514 RLIFID 519
>NP_079384
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CSKRLV 6
          CS+RLV
Sbjct: 6  CSRRLV 11
>XP_005260574
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSKRLVFI 8
           C K +VFI
Sbjct: 481 CPKTIVFI 488
>XP_006722542
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSKRLVFI 8
           CS  LVF+
Sbjct: 381 CSSGLVFV 388
>XP_005258336
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSKRLVFI 8
           CS  LVF+
Sbjct: 364 CSSGLVFV 371
>XP_005258335
          Length = 1295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSKRLVFI 8
           CS  LVF+
Sbjct: 381 CSSGLVFV 388
>XP_005258334
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CSKRLVFI 8
           CS  LVF+
Sbjct: 381 CSSGLVFV 388
>XP_006721018
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CSKRLV 6
          CS+RLV
Sbjct: 6  CSRRLV 11
>XP_006712321
          Length = 1307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RLVFID 9
           RL+FID
Sbjct: 515 RLIFID 520
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.152    0.494 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 518,195
Number of extensions: 1158
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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