Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           19     665
NP_000240                                                              19     665
NP_001161089                                                           19     665
XP_005265218                                                           19     665
XP_006716126                                                           18    1935
XP_005250566                                                           18    1935
XP_005250565                                                           18    1935
NP_001120829                                                           18    1935
NP_001120830                                                           18    1935
NP_065165                                                              18    1935
NP_004645                                                              17    4312
NP_079279                                                              17    4312
NP_003961                                                              17    4312
NP_001034680                                                           17    4312
NP_001034679                                                           17    4312
XP_005272733                                                           17    4312
XP_005272732                                                           17    4312
XP_006716300                                                           17    4312
NP_001167554                                                           16    5631
NP_001167553                                                           16    5631
NP_060322                                                              16    5631
NP_001167552                                                           16    5631
NP_000515                                                              16    7355
NP_003704                                                              16    7355
NP_060639                                                              16    7355
XP_006719162                                                           16    7355
XP_005253462                                                           16    7355
NP_006197                                                              15    9605
NP_000673                                                              15    9605
NP_000543                                                              15    9605
NP_002196                                                              15    9605
NP_061869                                                              15    9605
NP_001136112                                                           15    9605
NP_057416                                                              15    9605
NP_001004439                                                           15    9605
NP_006134                                                              15    9605
NP_775871                                                              15    9605
XP_006726646                                                           15    9605
XP_006722063                                                           15    9605
XP_006722062                                                           15    9605
XP_006722061                                                           15    9605
XP_006722060                                                           15    9605
XP_005257605                                                           15    9605
XP_005257604                                                           15    9605
XP_006722059                                                           15    9605
XP_005254285                                                           15    9605
XP_006714104                                                           15    9605
XP_005265800                                                           15    9605
XP_006714103                                                           15    9605
XP_006714102                                                           15    9605
NP_115267                                                              15    9605
NP_061746                                                              15    9605
>NP_001245200
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SIFGNAVS 9
           SIFGNAVS
Sbjct: 218 SIFGNAVS 225
>NP_000240
          Length = 756

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SIFGNAVS 9
           SIFGNAVS
Sbjct: 218 SIFGNAVS 225
>NP_001161089
          Length = 658

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SIFGNAVS 9
           SIFGNAVS
Sbjct: 120 SIFGNAVS 127
>XP_005265218
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SIFGNAVS 9
           SIFGNAVS
Sbjct: 218 SIFGNAVS 225
>XP_006716126
          Length = 708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IFGNAVS 9
           IFGNAVS
Sbjct: 424 IFGNAVS 430
>XP_005250566
          Length = 751

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IFGNAVS 9
           IFGNAVS
Sbjct: 467 IFGNAVS 473
>XP_005250565
          Length = 751

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IFGNAVS 9
           IFGNAVS
Sbjct: 467 IFGNAVS 473
>NP_001120829
          Length = 751

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IFGNAVS 9
           IFGNAVS
Sbjct: 467 IFGNAVS 473
>NP_001120830
          Length = 747

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IFGNAVS 9
           IFGNAVS
Sbjct: 463 IFGNAVS 469
>NP_065165
          Length = 747

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   IFGNAVS 9
           IFGNAVS
Sbjct: 463 IFGNAVS 469
>NP_004645
          Length = 2555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSIFGNA 7
           CS+FG A
Sbjct: 578 CSLFGEA 584
>NP_079279
          Length = 1910

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SIFGNAV 8
            +IFGNAV
Sbjct: 1824 TIFGNAV 1830
>NP_003961
          Length = 1465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CSIFGN 6
            C++FGN
Sbjct: 1366 CTVFGN 1371
>NP_001034680
          Length = 2554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSIFGNA 7
           CS+FG A
Sbjct: 577 CSLFGEA 583
>NP_001034679
          Length = 2570

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSIFGNA 7
           CS+FG A
Sbjct: 577 CSLFGEA 583
>XP_005272733
          Length = 2559

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSIFGNA 7
           CS+FG A
Sbjct: 577 CSLFGEA 583
>XP_005272732
          Length = 2575

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSIFGNA 7
           CS+FG A
Sbjct: 577 CSLFGEA 583
>XP_006716300
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    CSIFGN 6
            C++FGN
Sbjct: 1346 CTVFGN 1351
>NP_001167554
          Length = 1039

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CSIFGN 6
           CSIFG+
Sbjct: 669 CSIFGS 674
>NP_001167553
          Length = 1040

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CSIFGN 6
           CSIFG+
Sbjct: 670 CSIFGS 675
>NP_060322
          Length = 1062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CSIFGN 6
           CSIFG+
Sbjct: 692 CSIFGS 697
>NP_001167552
          Length = 1062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CSIFGN 6
           CSIFG+
Sbjct: 692 CSIFGS 697
>NP_000515
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CSIFGNA 7
          C++ GNA
Sbjct: 49 CAVLGNA 55
>NP_003704
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSIFGNAVS 9
           C +FG A+S
Sbjct: 132 CFLFGCAIS 140
>NP_060639
          Length = 1747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSIFGNAVS 9
           CS+ GN+ S
Sbjct: 717 CSVVGNSNS 725
>XP_006719162
          Length = 1676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSIFGNAVS 9
           CS+ GN+ S
Sbjct: 717 CSVVGNSNS 725
>XP_005253462
          Length = 1747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSIFGNAVS 9
           CS+ GN+ S
Sbjct: 717 CSVVGNSNS 725
>NP_006197
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CSIFGNAV 8
           C++F N V
Sbjct: 235 CAVFNNEV 242
>NP_000673
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SIFGNAV 8
          +IFGNA+
Sbjct: 26 TIFGNAL 32
>NP_000543
          Length = 2813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1  CSIFGN 6
          CS+FG+
Sbjct: 35 CSLFGS 40
>NP_002196
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CSIFGNAVS 9
           CS+ GN V+
Sbjct: 513 CSLEGNPVA 521
>NP_061869
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSIFGNA 7
           CS +GNA
Sbjct: 913 CSSWGNA 919
>NP_001136112
          Length = 1726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CSIFGNA 7
           CS +GNA
Sbjct: 910 CSSWGNA 916
>NP_057416
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1  CSIFGNAV 8
          CS FG  V
Sbjct: 4  CSFFGGEV 11
>NP_001004439
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    CSIFGNA 7
            C+I+GN+
Sbjct: 1034 CNIWGNS 1040
>NP_006134
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SIFGNAV 8
          SIFGN++
Sbjct: 79 SIFGNSL 85
>NP_775871
          Length = 8384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    CSIFGNAV 8
            C+I GN V
Sbjct: 1048 CTILGNYV 1055
>XP_006726646
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   CSIFGNA 7
           C IFG A
Sbjct: 400 CRIFGTA 406
>XP_006722063
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CSIFGNA 7
            CS +GNA
Sbjct: 1146 CSSWGNA 1152
>XP_006722062
          Length = 1866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CSIFGNA 7
            CS +GNA
Sbjct: 1149 CSSWGNA 1155
>XP_006722061
          Length = 1913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CSIFGNA 7
            CS +GNA
Sbjct: 1149 CSSWGNA 1155
>XP_006722060
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CSIFGNA 7
            CS +GNA
Sbjct: 1149 CSSWGNA 1155
>XP_005257605
          Length = 1926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CSIFGNA 7
            CS +GNA
Sbjct: 1149 CSSWGNA 1155
>XP_005257604
          Length = 1962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CSIFGNA 7
            CS +GNA
Sbjct: 1146 CSSWGNA 1152
>XP_006722059
          Length = 1965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CSIFGNA 7
            CS +GNA
Sbjct: 1149 CSSWGNA 1155
>XP_005254285
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CSIFGNA 7
           C+I+GN+
Sbjct: 932 CNIWGNS 938
>XP_006714104
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CSIFGNAV 8
           C++F N V
Sbjct: 260 CAVFNNEV 267
>XP_005265800
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CSIFGNAV 8
           C++F N V
Sbjct: 235 CAVFNNEV 242
>XP_006714103
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CSIFGNAV 8
           C++F N V
Sbjct: 257 CAVFNNEV 264
>XP_006714102
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   CSIFGNAV 8
           C++F N V
Sbjct: 260 CAVFNNEV 267
>NP_115267
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1   CSIFGNA 7
           C + GNA
Sbjct: 384 CQVLGNA 390
>NP_061746
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1   CSIFGNA 7
           C + GNA
Sbjct: 384 CQVLGNA 390
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.134    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 531,897
Number of extensions: 1241
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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