Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           21     229
NP_055903                                                              21     229
NP_001139138                                                           17    4312
NP_001139139                                                           17    4312
NP_036333                                                              17    4312
NP_057063                                                              17    4312
NP_004821                                                              17    4312
NP_001257451                                                           17    4312
NP_001257450                                                           17    4312
XP_006715675                                                           17    4312
XP_005267280                                                           17    4312
NP_066566                                                              16    5631
NP_001018024                                                           16    5631
NP_001263647                                                           16    5631
NP_653267                                                              16    5631
NP_001122100                                                           16    5631
NP_001263646                                                           16    5631
NP_064553                                                              16    5631
NP_001122101                                                           16    5631
XP_006724097                                                           16    5631
NP_001271282                                                           16    7355
NP_001271281                                                           16    7355
NP_065826                                                              16    7355
NP_001253977                                                           16    7355
NP_055836                                                              16    7355
NP_653280                                                              16    7355
XP_005259010                                                           16    7355
XP_006721775                                                           16    7355
XP_006721774                                                           16    7355
XP_006721773                                                           16    7355
XP_005257124                                                           16    7355
XP_006721772                                                           16    7355
XP_005257123                                                           16    7355
NP_001053                                                              16    7355
NP_872599                                                              15    9605
NP_005215                                                              15    9605
NP_001265247                                                           15    9605
NP_006854                                                              15    9605
NP_056150                                                              15    9605
NP_859052                                                              15    9605
NP_777551                                                              15    9605
NP_001265248                                                           15    9605
NP_001008781                                                           15    9605
XP_006726237                                                           15    9605
XP_006726236                                                           15    9605
XP_006726235                                                           15    9605
XP_006726234                                                           15    9605
XP_006726360                                                           15    9605
XP_006726359                                                           15    9605
XP_006726358                                                           15    9605
XP_006726357                                                           15    9605
XP_006726324                                                           15    9605
XP_006726323                                                           15    9605
XP_006726322                                                           15    9605
XP_006726321                                                           15    9605
XP_006723045                                                           15    9605
XP_006723044                                                           15    9605
XP_006723043                                                           15    9605
XP_006723042                                                           15    9605
XP_005259570                                                           15    9605
XP_005259571                                                           15    9605
XP_005259569                                                           15    9605
XP_006719370                                                           15    9605
XP_006719369                                                           15    9605
XP_006719368                                                           15    9605
XP_006718827                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   CQAVLQTIL 9
           CQAVLQT+L
Sbjct: 600 CQAVLQTLL 608
>NP_055903
          Length = 1723

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   CQAVLQTIL 9
           CQAVLQT+L
Sbjct: 600 CQAVLQTLL 608
>NP_001139138
          Length = 1192

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQAVLQTIL 9
           CQ  LQT++
Sbjct: 469 CQQALQTLI 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CQAVLQT 7
           C++V+QT
Sbjct: 496 CESVIQT 502
>NP_001139139
          Length = 1179

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQAVLQTIL 9
           CQ  LQT++
Sbjct: 480 CQQALQTLI 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CQAVLQT 7
           C++V+QT
Sbjct: 507 CESVIQT 513
>NP_036333
          Length = 1203

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQAVLQTIL 9
           CQ  LQT++
Sbjct: 480 CQQALQTLI 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   CQAVLQT 7
           C++V+QT
Sbjct: 507 CESVIQT 513
>NP_057063
          Length = 1365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CQAVLQTIL 9
           C+ +LQTI+
Sbjct: 718 CKDILQTIM 726
>NP_004821
          Length = 1368

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CQAVLQTIL 9
           C+ +LQTI+
Sbjct: 712 CKDILQTIM 720
>NP_001257451
          Length = 1364

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CQAVLQTIL 9
           C+ +LQTI+
Sbjct: 712 CKDILQTIM 720
>NP_001257450
          Length = 1359

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CQAVLQTIL 9
           C+ +LQTI+
Sbjct: 712 CKDILQTIM 720
>XP_006715675
          Length = 747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CQAVLQTIL 9
           C+ +LQTI+
Sbjct: 718 CKDILQTIM 726
>XP_005267280
          Length = 1374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CQAVLQTIL 9
           C+ +LQTI+
Sbjct: 718 CKDILQTIM 726
>NP_066566
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QAVLQTIL 9
           QAV QTIL
Sbjct: 182 QAVYQTIL 189
>NP_001018024
          Length = 68

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  CQAVLQTI 8
          CQAV+Q +
Sbjct: 28 CQAVIQEL 35
>NP_001263647
          Length = 636

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 507 CEAVLQAL 514
>NP_653267
          Length = 4753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQAVLQTI 8
            CQ VL+T+
Sbjct: 2468 CQPVLETL 2475
>NP_001122100
          Length = 681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 507 CEAVLQAL 514
>NP_001263646
          Length = 681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 507 CEAVLQAL 514
>NP_064553
          Length = 681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 507 CEAVLQAL 514
>NP_001122101
          Length = 681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 507 CEAVLQAL 514
>XP_006724097
          Length = 623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CQAVLQTIL 9
           CQ V  TIL
Sbjct: 600 CQEVFHTIL 608
>NP_001271282
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQAVLQTIL 9
           C A+L T+L
Sbjct: 580 CTAILLTVL 588
>NP_001271281
          Length = 902

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQAVLQTIL 9
           C A+L T+L
Sbjct: 816 CTAILLTVL 824
>NP_065826
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQAVLQTIL 9
           C A+L T+L
Sbjct: 918 CTAILLTVL 926
>NP_001253977
          Length = 926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CQAVLQTIL 9
           C A+L T+L
Sbjct: 831 CTAILLTVL 839
>NP_055836
          Length = 2723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  CQAVLQTIL 9
          CQ + QT+L
Sbjct: 51 CQQLCQTLL 59
>NP_653280
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 278 CEAVLQLL 285
>XP_005259010
          Length = 1261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    CQAVLQT 7
            CQA L+T
Sbjct: 1252 CQATLET 1258
>XP_006721775
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 194 CEAVLQLL 201
>XP_006721774
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 194 CEAVLQLL 201
>XP_006721773
          Length = 588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 341 CEAVLQLL 348
>XP_005257124
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 346 CEAVLQLL 353
>XP_006721772
          Length = 595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 348 CEAVLQLL 355
>XP_005257123
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   CQAVLQTI 8
           C+AVLQ +
Sbjct: 556 CEAVLQLL 563
>NP_001053
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CQAVLQTIL 9
           CQ  L T+L
Sbjct: 265 CQQTLNTVL 273
>NP_872599
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  CQAVLQTI 8
          CQ +L+T+
Sbjct: 21 CQELLETV 28
>NP_005215
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QAVLQTIL 9
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>NP_001265247
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 49 CQGILET 55
>NP_006854
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 49 CQGILET 55
>NP_056150
          Length = 2210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQAVLQTI 8
            CQ +LQT+
Sbjct: 1729 CQYMLQTM 1736
>NP_859052
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QAVLQTI 8
           QAVLQT+
Sbjct: 460 QAVLQTM 466
>NP_777551
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   CQAVLQTIL 9
           C+A++QT L
Sbjct: 265 CKALIQTKL 273
>NP_001265248
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 49 CQGILET 55
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QAVLQTIL 9
            QAV +TIL
Sbjct: 1885 QAVFETIL 1892
>XP_006726237
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726236
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726235
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726234
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726360
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726359
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726358
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726357
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726324
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726323
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726322
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006726321
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006723045
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006723044
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006723043
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_006723042
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  CQAVLQT 7
          CQ +L+T
Sbjct: 66 CQGILET 72
>XP_005259570
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QAVLQTIL 9
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>XP_005259571
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QAVLQTIL 9
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>XP_005259569
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QAVLQTIL 9
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>XP_006719370
          Length = 2076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQAVLQTI 8
            CQ +LQT+
Sbjct: 1595 CQYMLQTM 1602
>XP_006719369
          Length = 2200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQAVLQTI 8
            CQ +LQT+
Sbjct: 1719 CQYMLQTM 1726
>XP_006719368
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    CQAVLQTI 8
            CQ +LQT+
Sbjct: 1728 CQYMLQTM 1735
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QAVLQTIL 9
           QAV +TIL
Sbjct: 775 QAVFETIL 782
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.138    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 355,267
Number of extensions: 698
Number of successful extensions: 69
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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