Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_150241                                                              18    1482
XP_006712559                                                           17    3301
NP_072088                                                              17    3301
NP_062819                                                              16    5631
NP_000869                                                              16    7355
NP_001243778                                                           16    7355
NP_002682                                                              16    7355
NP_001265478                                                           16    7355
NP_002601                                                              16    7355
NP_001266282                                                           16    7355
NP_001266284                                                           16    7355
NP_009190                                                              16    7355
NP_001266283                                                           16    7355
XP_005259065                                                           16    7355
XP_006723311                                                           16    7355
XP_005259064                                                           16    7355
XP_005259063                                                           16    7355
XP_006719746                                                           16    7355
XP_005253685                                                           16    7355
XP_005253684                                                           16    7355
XP_006712658                                                           16    7355
XP_006712657                                                           16    7355
XP_006711205                                                           16    7355
NP_003950                                                              16    7355
NP_940980                                                              15    9605
NP_001034930                                                           15    9605
NP_001273409                                                           15    9605
NP_055598                                                              15    9605
NP_061940                                                              15    9605
NP_001171748                                                           15    9605
NP_079034                                                              15    9605
NP_078886                                                              15    9605
NP_002635                                                              15    9605
NP_056137                                                              15    9605
NP_031363                                                              15    9605
NP_031361                                                              15    9605
NP_115548                                                              15    9605
NP_955389                                                              15    9605
NP_001273408                                                           15    9605
XP_006725628                                                           15    9605
XP_006725627                                                           15    9605
XP_005255358                                                           15    9605
XP_005255357                                                           15    9605
XP_005255356                                                           15    9605
XP_005255355                                                           15    9605
XP_006720851                                                           15    9605
XP_005254865                                                           15    9605
XP_005268686                                                           15    9605
XP_005249939                                                           15    9605
XP_005247818                                                           15    9605
XP_006713504                                                           15    9605
XP_006713503                                                           15    9605
XP_005265688                                                           15    9605
XP_006713502                                                           15    9605
XP_006713501                                                           15    9605
XP_006713500                                                           15    9605
XP_005265687                                                           15    9605
XP_006712096                                                           15    9605
XP_005264430                                                           15    9605
XP_006712093                                                           15    9605
XP_005264429                                                           15    9605
XP_005273220                                                           15    9605
NP_001138483                                                           15    9605
NP_060022                                                              15    9605
NP_001229267                                                           15    9605
>NP_150241
          Length = 882

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C LLEVS G
Sbjct: 754 CRLLEVSPG 762
>XP_006712559
          Length = 191

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CNLLEVSQG 9
          CN L +SQG
Sbjct: 6  CNSLTLSQG 14
>NP_072088
          Length = 362

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LLEVSQG 9
           LLEVSQG
Sbjct: 180 LLEVSQG 186
>NP_062819
          Length = 109

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  CNLLEVSQG 9
          CNLL  S+G
Sbjct: 78 CNLLIKSEG 86
>NP_000869
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CNLLEVSQ 8
          C LL VSQ
Sbjct: 74 CELLPVSQ 81
>NP_001243778
          Length = 1107

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CNLLEVSQ 8
           CN +++SQ
Sbjct: 873 CNRIDISQ 880
>NP_002682
          Length = 1107

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CNLLEVSQ 8
           CN +++SQ
Sbjct: 873 CNRIDISQ 880
>NP_001265478
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CNLLEV 6
           CN+LEV
Sbjct: 243 CNVLEV 248
>NP_002601
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CNLLEV 6
           CN+LEV
Sbjct: 223 CNVLEV 228
>NP_001266282
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NLLEVSQ 8
           NLLEVS+
Sbjct: 241 NLLEVSE 247
>NP_001266284
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NLLEVSQ 8
           NLLEVS+
Sbjct: 223 NLLEVSE 229
>NP_009190
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NLLEVSQ 8
           NLLEVS+
Sbjct: 346 NLLEVSE 352
>NP_001266283
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NLLEVSQ 8
           NLLEVS+
Sbjct: 310 NLLEVSE 316
>XP_005259065
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CNLLEVSQ 8
           CN +++SQ
Sbjct: 849 CNRIDISQ 856
>XP_006723311
          Length = 1109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CNLLEVSQ 8
           CN +++SQ
Sbjct: 875 CNRIDISQ 882
>XP_005259064
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CNLLEVSQ 8
           CN +++SQ
Sbjct: 899 CNRIDISQ 906
>XP_005259063
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CNLLEVSQ 8
           CN +++SQ
Sbjct: 899 CNRIDISQ 906
>XP_006719746
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NL+E+S G
Sbjct: 305 NLIEISTG 312
>XP_005253685
          Length = 1061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NL+E+S G
Sbjct: 305 NLIEISTG 312
>XP_005253684
          Length = 1073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NL+E+S G
Sbjct: 317 NLIEISTG 324
>XP_006712658
          Length = 244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CNLLEV 6
          CN+LEV
Sbjct: 31 CNVLEV 36
>XP_006712657
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CNLLEV 6
           CN+LEV
Sbjct: 243 CNVLEV 248
>XP_006711205
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NLLEVSQ 8
           NLLEVS+
Sbjct: 346 NLLEVSE 352
>NP_003950
          Length = 1068

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NL+E+S G
Sbjct: 317 NLIEISTG 324
>NP_940980
          Length = 2527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  CNLLEVSQG 9
          C L+EV  G
Sbjct: 86 CKLIEVCPG 94
>NP_001034930
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NLL+ S+G
Sbjct: 202 NLLQTSEG 209
>NP_001273409
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NLLEVSQG 9
          NLL+ S+G
Sbjct: 13 NLLQTSEG 20
>NP_055598
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NLL+ S+G
Sbjct: 202 NLLQTSEG 209
>NP_061940
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CNLLEVS 7
           CNL E+S
Sbjct: 342 CNLEEIS 348
>NP_001171748
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CNLLEVS 7
           CNL E+S
Sbjct: 342 CNLEEIS 348
>NP_079034
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   CNLLEVS 7
           C+L+EVS
Sbjct: 316 CDLVEVS 322
>NP_078886
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CNLLEVSQ 8
           CN +EV Q
Sbjct: 362 CNHMEVGQ 369
>NP_002635
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEVSQG 9
           LEVSQG
Sbjct: 125 LEVSQG 130
>NP_056137
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   CNLLEVSQ 8
           C++LE+ Q
Sbjct: 413 CSVLEIEQ 420
>NP_031363
          Length = 1778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 799 CHIIEVEPG 807
>NP_031361
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 799 CHIIEVEPG 807
>NP_115548
          Length = 1316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1    CNLLEVSQG 9
            C L E  QG
Sbjct: 1307 CRLFEYGQG 1315
>NP_955389
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NLL+ S+G
Sbjct: 202 NLLQTSEG 209
>NP_001273408
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NLLEVSQG 9
          NLL+ S+G
Sbjct: 13 NLLQTSEG 20
>XP_006725628
          Length = 994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NLL+ S+G
Sbjct: 202 NLLQTSEG 209
>XP_006725627
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NLL+ S+G
Sbjct: 202 NLLQTSEG 209
>XP_005255358
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLEVSQG 9
           LLE SQG
Sbjct: 107 LLEASQG 113
>XP_005255357
          Length = 1112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLEVSQG 9
           LLE SQG
Sbjct: 107 LLEASQG 113
>XP_005255356
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLEVSQG 9
           LLE SQG
Sbjct: 107 LLEASQG 113
>XP_005255355
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLEVSQG 9
           LLE SQG
Sbjct: 107 LLEASQG 113
>XP_006720851
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NLLEVSQG 9
          NLL+ S+G
Sbjct: 13 NLLQTSEG 20
>XP_005254865
          Length = 994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLEVSQG 9
           NLL+ S+G
Sbjct: 202 NLLQTSEG 209
>XP_005268686
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  CNLLEVSQG 9
          C L+EV  G
Sbjct: 86 CKLIEVCPG 94
>XP_005249939
          Length = 1324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1    CNLLEVSQG 9
            C L E  QG
Sbjct: 1307 CRLFEYGQG 1315
>XP_005247818
          Length = 460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CNLLEVSQ 8
           CN +EV Q
Sbjct: 334 CNHMEVGQ 341
>XP_006713504
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 96  CHIIEVEPG 104
>XP_006713503
          Length = 1438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 799 CHIIEVEPG 807
>XP_005265688
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 498 CHIIEVEPG 506
>XP_006713502
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 799 CHIIEVEPG 807
>XP_006713501
          Length = 1727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 799 CHIIEVEPG 807
>XP_006713500
          Length = 1746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 799 CHIIEVEPG 807
>XP_005265687
          Length = 1758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CNLLEVSQG 9
           C+++EV  G
Sbjct: 799 CHIIEVEPG 807
>XP_006712096
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   CNLLEVSQG 9
           C+++++ QG
Sbjct: 554 CDIMDLDQG 562
>XP_005264430
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   CNLLEVSQG 9
           C+++++ QG
Sbjct: 796 CDIMDLDQG 804
>XP_006712093
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CNLLEVSQG 9
            C+++++ QG
Sbjct: 1224 CDIMDLDQG 1232
>XP_005264429
          Length = 1472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CNLLEVSQG 9
            C+++++ QG
Sbjct: 1224 CDIMDLDQG 1232
>XP_005273220
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEVSQG 9
           LEVSQG
Sbjct: 125 LEVSQG 130
>NP_001138483
          Length = 1141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLEVSQG 9
           LLE SQG
Sbjct: 107 LLEASQG 113
>NP_060022
          Length = 1458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CNLLEVSQG 9
            C+++++ QG
Sbjct: 1210 CDIMDLDQG 1218
>NP_001229267
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    CNLLEVSQG 9
            C+++++ QG
Sbjct: 1205 CDIMDLDQG 1213
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 476,189
Number of extensions: 871
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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