Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689637                                                              17    4312
NP_001107                                                              17    4312
NP_573400                                                              17    4312
NP_001026908                                                           17    4312
XP_005262298                                                           17    4312
XP_006723752                                                           17    4312
XP_006723751                                                           17    4312
XP_006723750                                                           17    4312
XP_006723749                                                           17    4312
XP_006723748                                                           17    4312
XP_005255136                                                           17    4312
XP_006711995                                                           17    4312
XP_006711994                                                           17    4312
XP_006711993                                                           17    4312
NP_036336                                                              17    4312
NP_001129107                                                           16    5631
NP_113638                                                              16    5631
NP_002323                                                              16    7355
NP_000378                                                              16    7355
NP_005609                                                              16    7355
NP_940961                                                              16    7355
XP_006725077                                                           16    7355
XP_005266991                                                           16    7355
XP_006713390                                                           16    7355
XP_005246598                                                           16    7355
XP_005246596                                                           16    7355
NP_001035304                                                           15    9605
NP_060597                                                              15    9605
NP_001159434                                                           15    9605
NP_776065                                                              15    9605
NP_001127808                                                           15    9605
NP_065755                                                              15    9605
XP_006723721                                                           15    9605
XP_006723720                                                           15    9605
XP_006716133                                                           15    9605
XP_006716132                                                           15    9605
XP_005266891                                                           15    9605
XP_005266890                                                           15    9605
XP_006715232                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
NP_008955                                                              15    9605
NP_002277                                                              15    9605
>NP_689637
          Length = 1135

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CLLTYQ 6
           CL+TYQ
Sbjct: 361 CLVTYQ 366
>NP_001107
          Length = 1353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C L Y+A+T
Sbjct: 805 CFLKYEAAT 813
>NP_573400
          Length = 1460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLLT  AST
Sbjct: 740 CLLTTGAST 748
>NP_001026908
          Length = 271

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C L+YQ +T
Sbjct: 159 CALSYQGAT 167
>XP_005262298
          Length = 858

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  CLLTYQ 6
          CL+TYQ
Sbjct: 84 CLVTYQ 89
>XP_006723752
          Length = 1387

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLLT  AST
Sbjct: 677 CLLTTGAST 685
>XP_006723751
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLLT  AST
Sbjct: 666 CLLTTGAST 674
>XP_006723750
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLLT  AST
Sbjct: 666 CLLTTGAST 674
>XP_006723749
          Length = 1428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLLT  AST
Sbjct: 677 CLLTTGAST 685
>XP_006723748
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLLT  AST
Sbjct: 677 CLLTTGAST 685
>XP_005255136
          Length = 1372

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C L Y+A+T
Sbjct: 824 CFLKYEAAT 832
>XP_006711995
          Length = 218

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C L+YQ +T
Sbjct: 106 CALSYQGAT 114
>XP_006711994
          Length = 271

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C L+YQ +T
Sbjct: 159 CALSYQGAT 167
>XP_006711993
          Length = 271

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C L+YQ +T
Sbjct: 159 CALSYQGAT 167
>NP_036336
          Length = 822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   CLLTYQA 7
           C LTYQ+
Sbjct: 773 CFLTYQS 779
>NP_001129107
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CLLTYQ 6
           CLLTY+
Sbjct: 241 CLLTYK 246
>NP_113638
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   CLLTYQ 6
           CLLTY+
Sbjct: 240 CLLTYK 245
>NP_002323
          Length = 4544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    CLLTYQ 6
            CLLT+Q
Sbjct: 2493 CLLTHQ 2498
>NP_000378
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLL  QAS+
Sbjct: 136 CLLQIQASS 144
>NP_005609
          Length = 723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CLLTYQAS 8
          CL  YQAS
Sbjct: 63 CLKHYQAS 70
>NP_940961
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           C LTYQ
Sbjct: 206 CYLTYQ 211
>XP_006725077
          Length = 524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CLLTYQAS 8
          CL  YQAS
Sbjct: 63 CLKHYQAS 70
>XP_005266991
          Length = 524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  CLLTYQAS 8
          CL  YQAS
Sbjct: 63 CLKHYQAS 70
>XP_006713390
          Length = 184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           CLL  QAS+
Sbjct: 136 CLLQIQASS 144
>XP_005246598
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           C LTYQ
Sbjct: 108 CYLTYQ 113
>XP_005246596
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           C LTYQ
Sbjct: 175 CYLTYQ 180
>NP_001035304
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           CLL YQ
Sbjct: 139 CLLEYQ 144
>NP_060597
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           CLL YQ
Sbjct: 421 CLLKYQ 426
>NP_001159434
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           CLL YQ
Sbjct: 381 CLLKYQ 386
>NP_776065
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           CLL YQ
Sbjct: 420 CLLKYQ 425
>NP_001127808
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   CLLTYQAST 9
           C L YQ  T
Sbjct: 156 CFLLYQMGT 164
>NP_065755
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   CLLTYQAST 9
           C L YQ  T
Sbjct: 156 CFLLYQMGT 164
>XP_006723721
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C++ YQ S+
Sbjct: 484 CMMPYQQSS 492
>XP_006723720
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CLLTYQAST 9
           C++ YQ S+
Sbjct: 702 CMMPYQQSS 710
>XP_006716133
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   CLLTYQAST 9
           C L YQ  T
Sbjct: 156 CFLLYQMGT 164
>XP_006716132
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   CLLTYQAST 9
           C L YQ  T
Sbjct: 156 CFLLYQMGT 164
>XP_005266891
          Length = 190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           CLL YQ
Sbjct: 139 CLLEYQ 144
>XP_005266890
          Length = 207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CLLTYQ 6
           CLL YQ
Sbjct: 138 CLLEYQ 143
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1813 ILTYQVQT 1820
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1487 ILTYQVQT 1494
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1813 ILTYQVQT 1820
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1839 ILTYQVQT 1846
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1846 ILTYQVQT 1853
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1853 ILTYQVQT 1860
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1886 ILTYQVQT 1893
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1929 ILTYQVQT 1936
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 1991 ILTYQVQT 1998
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 2003 ILTYQVQT 2010
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LLTYQAST 9
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>NP_008955
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LLTYQAS 8
           LLTY AS
Sbjct: 118 LLTYMAS 124
>NP_002277
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CLLTYQ 6
           C+LTY+
Sbjct: 241 CILTYR 246
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.124    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,874
Number of extensions: 753
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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