Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              22     134
XP_005266703                                                           22     134
NP_001028752                                                           17    2528
NP_079385                                                              17    2528
NP_001157207                                                           17    2528
XP_006725416                                                           17    2528
XP_006725415                                                           17    2528
XP_006725414                                                           17    2528
XP_006722172                                                           17    2528
XP_006722171                                                           17    2528
XP_006722170                                                           17    2528
NP_037506                                                              17    4312
NP_001155901                                                           17    4312
NP_001804                                                              16    5631
NP_001273663                                                           16    5631
NP_001070731                                                           16    5631
NP_588613                                                              16    5631
NP_001008738                                                           16    5631
NP_001193719                                                           16    5631
NP_001231924                                                           16    5631
NP_001193718                                                           16    5631
NP_000123                                                              16    7355
NP_001074299                                                           16    7355
NP_078772                                                              16    7355
NP_057081                                                              16    7355
XP_005245292                                                           16    7355
XP_005245291                                                           16    7355
NP_001243599                                                           15    9605
NP_569710                                                              15    9605
NP_005691                                                              15    9605
NP_065188                                                              15    9605
NP_001027566                                                           15    9605
NP_001027567                                                           15    9605
NP_940971                                                              15    9605
NP_116212                                                              15    9605
NP_036434                                                              15    9605
NP_001180258                                                           15    9605
XP_006717369                                                           15    9605
XP_005267118                                                           15    9605
XP_006715581                                                           15    9605
XP_006715580                                                           15    9605
XP_006715579                                                           15    9605
XP_005270731                                                           15    9605
XP_005270730                                                           15    9605
XP_006710560                                                           15    9605
XP_006710559                                                           15    9605
XP_006710558                                                           15    9605
XP_006710557                                                           15    9605
XP_006710556                                                           15    9605
XP_006710555                                                           15    9605
XP_005270727                                                           15    9605
XP_006710554                                                           15    9605
XP_005270725                                                           15    9605
XP_005270724                                                           15    9605
XP_006710553                                                           15    9605
XP_005270723                                                           15    9605
XP_006710552                                                           15    9605
XP_006710551                                                           15    9605
XP_006710550                                                           15    9605
XP_006710549                                                           15    9605
XP_006710548                                                           15    9605
>NP_443179
          Length = 2170

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    CFQATRET 8
            CFQATRET
Sbjct: 998  CFQATRET 1005
>XP_005266703
          Length = 1501

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   CFQATRET 8
           CFQATRET
Sbjct: 329 CFQATRET 336
>NP_001028752
          Length = 317

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 275 CFEVTREAM 283
>NP_079385
          Length = 770

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 275 CFEVTREAM 283
>NP_001157207
          Length = 970

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 275 CFEVTREAM 283
>XP_006725416
          Length = 808

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 113 CFEVTREAM 121
>XP_006725415
          Length = 990

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 275 CFEVTREAM 283
>XP_006725414
          Length = 1034

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 275 CFEVTREAM 283
>XP_006722172
          Length = 808

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 113 CFEVTREAM 121
>XP_006722171
          Length = 972

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 275 CFEVTREAM 283
>XP_006722170
          Length = 1016

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF+ TRE +
Sbjct: 275 CFEVTREAM 283
>NP_037506
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CFQATRETV 9
           C+Q+ R+T+
Sbjct: 512 CYQSHRDTI 520
>NP_001155901
          Length = 873

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   CFQATRETV 9
           C+Q+ R+T+
Sbjct: 517 CYQSHRDTI 525
>NP_001804
          Length = 2701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CFQATRETV 9
            C + T+ET+
Sbjct: 2431 CLEKTKETI 2439
>NP_001273663
          Length = 2580

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    CFQATRETV 9
            C + T+ET+
Sbjct: 2310 CLEKTKETI 2318
>NP_001070731
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF  TRE V
Sbjct: 367 CFFVTREKV 375
>NP_588613
          Length = 1166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF A  ETV
Sbjct: 673 CFDAKLETV 681
>NP_001008738
          Length = 1138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF A  ETV
Sbjct: 645 CFDAKLETV 653
>NP_001193719
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF  TRE V
Sbjct: 367 CFFVTREKV 375
>NP_001231924
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF  TRE V
Sbjct: 367 CFFVTREKV 375
>NP_001193718
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF  TRE V
Sbjct: 332 CFFVTREKV 340
>NP_000123
          Length = 2351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  CFQATR 6
          CF ATR
Sbjct: 17 CFSATR 22
>NP_001074299
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           C QA  ETV
Sbjct: 289 CLQAPLETV 297
>NP_078772
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           CF  +RE++
Sbjct: 739 CFPCSRESI 747
>NP_057081
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           C++A  ETV
Sbjct: 340 CYRAALETV 348
>XP_005245292
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           C++A  ETV
Sbjct: 270 CYRAALETV 278
>XP_005245291
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   CFQATRETV 9
           C++A  ETV
Sbjct: 340 CYRAALETV 348
>NP_001243599
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF   R+TV
Sbjct: 624 CFLTLRDTV 632
>NP_569710
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF   R+TV
Sbjct: 654 CFLTLRDTV 662
>NP_005691
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   CFQATRETV 9
           CF   R+TV
Sbjct: 654 CFLTLRDTV 662
>NP_065188
          Length = 1221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 186 CFEATK 191
>NP_001027566
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 186 CFEATK 191
>NP_001027567
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 186 CFEATK 191
>NP_940971
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 186 CFEATK 191
>NP_116212
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   CFQATRE 7
           CF+ T+E
Sbjct: 699 CFERTKE 705
>NP_036434
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>NP_001180258
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   CFQATRE 7
           CF+ T+E
Sbjct: 798 CFERTKE 804
>XP_006717369
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   CFQATRE 7
           CF+ T+E
Sbjct: 798 CFERTKE 804
>XP_005267118
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 187 CFEATK 192
>XP_006715581
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 187 CFEATK 192
>XP_006715580
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 185 CFEATK 190
>XP_006715579
          Length = 1251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   CFQATR 6
           CF+AT+
Sbjct: 187 CFEATK 192
>XP_005270731
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>XP_005270730
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>XP_006710560
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710559
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710558
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710557
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710556
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710555
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>XP_005270727
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>XP_006710554
          Length = 1421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_005270725
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>XP_005270724
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>XP_006710553
          Length = 1451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_005270723
          Length = 1459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 298 FEATWETV 305
>XP_006710552
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710551
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710550
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710549
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
>XP_006710548
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQATRETV 9
           F+AT ETV
Sbjct: 303 FEATWETV 310
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.128    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,512
Number of extensions: 736
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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