Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              21     175
XP_006714104                                                           21     175
XP_005265800                                                           21     175
XP_006714103                                                           21     175
XP_006714102                                                           21     175
NP_057735                                                              18    1935
XP_006720230                                                           18    1935
XP_006720229                                                           18    1935
NP_001072988                                                           18    1935
NP_006816                                                              17    2528
NP_000386                                                              17    4312
XP_005261397                                                           17    4312
XP_006710230                                                           16    5631
NP_001265546                                                           16    7355
NP_001265545                                                           16    7355
NP_001138619                                                           16    7355
NP_005934                                                              16    7355
NP_001138618                                                           16    7355
NP_001138620                                                           16    7355
NP_004327                                                              16    7355
NP_001243228                                                           16    7355
NP_004373                                                              16    7355
NP_001068566                                                           16    7355
NP_003622                                                              15    9605
NP_004345                                                              15    9605
NP_079284                                                              15    9605
NP_694540                                                              15    9605
NP_061905                                                              15    9605
NP_001275537                                                           15    9605
NP_001275536                                                           15    9605
NP_003493                                                              15    9605
NP_851393                                                              15    9605
NP_073622                                                              15    9605
NP_001137450                                                           15    9605
NP_055906                                                              15    9605
NP_543137                                                              15    9605
NP_001265552                                                           15    9605
NP_872393                                                              15    9605
NP_001265553                                                           15    9605
XP_006724359                                                           15    9605
XP_005261762                                                           15    9605
XP_005261761                                                           15    9605
XP_005255730                                                           15    9605
XP_005255666                                                           15    9605
XP_005255665                                                           15    9605
XP_005255664                                                           15    9605
XP_006720146                                                           15    9605
XP_005267508                                                           15    9605
XP_006716171                                                           15    9605
XP_006716170                                                           15    9605
XP_006712515                                                           15    9605
XP_006712514                                                           15    9605
XP_006712513                                                           15    9605
XP_006712512                                                           15    9605
XP_006712511                                                           15    9605
XP_006712510                                                           15    9605
XP_006712509                                                           15    9605
XP_005246533                                                           15    9605
XP_006712508                                                           15    9605
XP_006711452                                                           15    9605
NP_942153                                                              15    9605
NP_115893                                                              15    9605
NP_776159                                                              15    9605
NP_116204                                                              15    9605
>NP_006197
          Length = 1089

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  CFGESEVS 8
          CFGESEVS
Sbjct: 49 CFGESEVS 56
>XP_006714104
          Length = 832

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  CFGESEVS 8
          CFGESEVS
Sbjct: 74 CFGESEVS 81
>XP_005265800
          Length = 1089

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  CFGESEVS 8
          CFGESEVS
Sbjct: 49 CFGESEVS 56
>XP_006714103
          Length = 1111

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  CFGESEVS 8
          CFGESEVS
Sbjct: 71 CFGESEVS 78
>XP_006714102
          Length = 1114

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  CFGESEVS 8
          CFGESEVS
Sbjct: 74 CFGESEVS 81
>NP_057735
          Length = 836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   CFGESEVS 8
           CFG+SE S
Sbjct: 753 CFGDSESS 760
>XP_006720230
          Length = 555

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   CFGESEVS 8
           CFG+SE S
Sbjct: 472 CFGDSESS 479
>XP_006720229
          Length = 747

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   CFGESEVS 8
           CFG+SE S
Sbjct: 664 CFGDSESS 671
>NP_001072988
          Length = 799

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   CFGESEVS 8
           CFG+SE S
Sbjct: 716 CFGDSESS 723
>NP_006816
          Length = 602

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   GESEVSR 9
           GESEVSR
Sbjct: 193 GESEVSR 199
>NP_000386
          Length = 897

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FGESEVS 8
           FG+SEVS
Sbjct: 529 FGDSEVS 535
>XP_005261397
          Length = 903

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FGESEVS 8
           FG+SEVS
Sbjct: 535 FGDSEVS 541
>XP_006710230
          Length = 332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FGESEVS 8
           FGE EVS
Sbjct: 178 FGEKEVS 184
>NP_001265546
          Length = 1028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FGESEVSR 9
           FGE  VSR
Sbjct: 553 FGERSVSR 560
>NP_001265545
          Length = 1065

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FGESEVSR 9
           FGE  VSR
Sbjct: 533 FGERSVSR 540
>NP_001138619
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE EVSR
Sbjct: 295 GEDEVSR 301
>NP_005934
          Length = 385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FGESEVS 8
           FG SEVS
Sbjct: 331 FGNSEVS 337
>NP_001138618
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE EVSR
Sbjct: 364 GEDEVSR 370
>NP_001138620
          Length = 401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE EVSR
Sbjct: 335 GEDEVSR 341
>NP_004327
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FGESEVSR 9
           FGE  VSR
Sbjct: 553 FGERSVSR 560
>NP_001243228
          Length = 240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE EVSR
Sbjct: 160 GEDEVSR 166
>NP_004373
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE EVSR
Sbjct: 335 GEDEVSR 341
>NP_001068566
          Length = 385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FGESEVS 8
           FG SEVS
Sbjct: 331 FGNSEVS 337
>NP_003622
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FGESEVSR 9
           FG+SE+ R
Sbjct: 902 FGDSELMR 909
>NP_004345
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   CFGESE 6
           CF ESE
Sbjct: 298 CFDESE 303
>NP_079284
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFGESEVSR 9
           C GESE  R
Sbjct: 364 CSGESEQLR 372
>NP_694540
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFGESEVS 8
           C G+ EVS
Sbjct: 641 CLGKHEVS 648
>NP_061905
          Length = 1074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFGESEVSR 9
           C GESE  R
Sbjct: 364 CSGESEQLR 372
>NP_001275537
          Length = 1097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFGESEVSR 9
           C GESE  R
Sbjct: 364 CSGESEQLR 372
>NP_001275536
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFGESEVSR 9
           C GESE  R
Sbjct: 364 CSGESEQLR 372
>NP_003493
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE E+SR
Sbjct: 639 GEKEISR 645
>NP_851393
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE E+SR
Sbjct: 639 GEKEISR 645
>NP_073622
          Length = 1501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   CFGESEVS 8
           C G  EVS
Sbjct: 248 CMGNQEVS 255
>NP_001137450
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FGESEVS 8
           FGESE S
Sbjct: 121 FGESESS 127
>NP_055906
          Length = 1720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   CFGESEVSR 9
           CF    VSR
Sbjct: 707 CFSRKRVSR 715
>NP_543137
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  CFGESEVS 8
          C G+SE S
Sbjct: 73 CAGQSEAS 80
>NP_001265552
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFGESEVS 8
           C G+ EVS
Sbjct: 641 CLGKHEVS 648
>NP_872393
          Length = 3234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1287 CHGESE 1292
>NP_001265553
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFGESEVS 8
           C G+ EVS
Sbjct: 641 CLGKHEVS 648
>XP_006724359
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   CFGESEVS 8
           C G  EVS
Sbjct: 248 CMGNQEVS 255
>XP_005261762
          Length = 1481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   CFGESEVS 8
           C G  EVS
Sbjct: 142 CMGNQEVS 149
>XP_005261761
          Length = 1587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   CFGESEVS 8
           C G  EVS
Sbjct: 248 CMGNQEVS 255
>XP_005255730
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   CFGESEVS 8
           C G+SE S
Sbjct: 128 CAGQSEAS 135
>XP_005255666
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE E+SR
Sbjct: 639 GEKEISR 645
>XP_005255665
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE E+SR
Sbjct: 688 GEKEISR 694
>XP_005255664
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GESEVSR 9
           GE E+SR
Sbjct: 688 GEKEISR 694
>XP_006720146
          Length = 1226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   CFGESEVSR 9
           CF    VSR
Sbjct: 707 CFSRKRVSR 715
>XP_005267508
          Length = 1773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   CFGESEVSR 9
           CF    VSR
Sbjct: 707 CFSRKRVSR 715
>XP_006716171
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFGESEVS 8
           CF  SEVS
Sbjct: 313 CFLNSEVS 320
>XP_006716170
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   CFGESEVS 8
           CF  SEVS
Sbjct: 376 CFLNSEVS 383
>XP_006712515
          Length = 3232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1285 CHGESE 1290
>XP_006712514
          Length = 2496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1290 CHGESE 1295
>XP_006712513
          Length = 3220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1186 CHGESE 1191
>XP_006712512
          Length = 3237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1290 CHGESE 1295
>XP_006712511
          Length = 3256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1290 CHGESE 1295
>XP_006712510
          Length = 3305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1290 CHGESE 1295
>XP_006712509
          Length = 3319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1285 CHGESE 1290
>XP_005246533
          Length = 3323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1290 CHGESE 1295
>XP_006712508
          Length = 3324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1290 CHGESE 1295
>XP_006711452
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   CFGESEVSR 9
           C GESE  R
Sbjct: 364 CSGESEQLR 372
>NP_942153
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   CFGESEVS 8
           C G  EVS
Sbjct: 96  CMGNQEVS 103
>NP_115893
          Length = 3258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    CFGESE 6
            C GESE
Sbjct: 1292 CHGESE 1297
>NP_776159
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FGESEVS 8
           FGESE S
Sbjct: 121 FGESESS 127
>NP_116204
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FGESEVS 8
           FGE+E+S
Sbjct: 308 FGETELS 314
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.132    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 591,267
Number of extensions: 668
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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