Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           19     869
NP_055903                                                              19     869
NP_060175                                                              16    7355
NP_001098024                                                           16    7355
NP_997198                                                              16    7355
XP_005254553                                                           16    7355
XP_005254552                                                           16    7355
XP_005254551                                                           16    7355
XP_006720646                                                           16    7355
NP_001106849                                                           15    9605
NP_060663                                                              15    9605
NP_079032                                                              15    9605
XP_005270210                                                           15    9605
XP_006718033                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AVLQTILSR 9
           AVLQT+LSR
Sbjct: 602 AVLQTLLSR 610
>NP_055903
          Length = 1723

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AVLQTILSR 9
           AVLQT+LSR
Sbjct: 602 AVLQTLLSR 610
>NP_060175
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AVLQTILS 8
           AVL TILS
Sbjct: 156 AVLNTILS 163
>NP_001098024
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AVLQTILS 8
           AVL TILS
Sbjct: 156 AVLNTILS 163
>NP_997198
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLQTILS 8
           VLQT+LS
Sbjct: 434 VLQTVLS 440
>XP_005254553
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  AVLQTILS 8
          AVL TILS
Sbjct: 41 AVLNTILS 48
>XP_005254552
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AVLQTILS 8
           AVL TILS
Sbjct: 142 AVLNTILS 149
>XP_005254551
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AVLQTILS 8
           AVL TILS
Sbjct: 156 AVLNTILS 163
>XP_006720646
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AVLQTILS 8
           AVL TILS
Sbjct: 156 AVLNTILS 163
>NP_001106849
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AVLQTILSR 9
           +V+QT+LS+
Sbjct: 622 SVMQTLLSQ 630
>NP_060663
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AVLQTILSR 9
           +V+QT+LS+
Sbjct: 622 SVMQTLLSQ 630
>NP_079032
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LQTILSR 9
           LQT+LSR
Sbjct: 773 LQTMLSR 779
>XP_005270210
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LQTILSR 9
           LQT+LSR
Sbjct: 712 LQTMLSR 718
>XP_006718033
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LQTILSR 9
           LQT+LSR
Sbjct: 712 LQTMLSR 718
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.134    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 285,199
Number of extensions: 447
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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