Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              20     509
XP_005251512                                                           20     509
NP_689704                                                              16    5631
NP_079169                                                              16    5631
XP_006723691                                                           16    5631
XP_006723690                                                           16    5631
XP_006723689                                                           16    5631
NP_003103                                                              16    7355
XP_005249886                                                           16    7355
XP_005249885                                                           16    7355
NP_115977                                                              15    9605
NP_003666                                                              15    9605
NP_056998                                                              15    9605
NP_005493                                                              15    9605
NP_001258358                                                           15    9605
NP_001258357                                                           15    9605
NP_055862                                                              15    9605
NP_001258356                                                           15    9605
NP_149047                                                              15    9605
NP_115935                                                              15    9605
NP_002636                                                              15    9605
NP_908975                                                              15    9605
NP_908974                                                              15    9605
NP_912730                                                              15    9605
NP_001026918                                                           15    9605
XP_005255403                                                           15    9605
XP_006719421                                                           15    9605
XP_005268863                                                           15    9605
XP_005253037                                                           15    9605
XP_005253036                                                           15    9605
XP_005253035                                                           15    9605
XP_005253034                                                           15    9605
XP_005252693                                                           15    9605
XP_005252691                                                           15    9605
XP_005251837                                                           15    9605
XP_005251835                                                           15    9605
XP_006717058                                                           15    9605
XP_005251833                                                           15    9605
XP_005251831                                                           15    9605
XP_005251830                                                           15    9605
XP_006716545                                                           15    9605
XP_005251373                                                           15    9605
XP_005264492                                                           15    9605
XP_006712116                                                           15    9605
XP_005245845                                                           15    9605
XP_005245844                                                           15    9605
NP_908973                                                              15    9605
>NP_004963
          Length = 1132

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           ATRNIL EN
Sbjct: 978 ATRNILVEN 986
>XP_005251512
          Length = 1132

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           ATRNIL EN
Sbjct: 978 ATRNILVEN 986
>NP_689704
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRNILAEN 9
           T+NI+A+N
Sbjct: 377 TKNIVADN 384
>NP_079169
          Length = 258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TRNILAEN 9
          TRN++AE+
Sbjct: 28 TRNLMAES 35
>XP_006723691
          Length = 256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TRNILAEN 9
          TRN++AE+
Sbjct: 28 TRNLMAES 35
>XP_006723690
          Length = 258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TRNILAEN 9
          TRN++AE+
Sbjct: 28 TRNLMAES 35
>XP_006723689
          Length = 258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TRNILAEN 9
          TRN++AE+
Sbjct: 28 TRNLMAES 35
>NP_003103
          Length = 784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           A+ NILA+N
Sbjct: 215 ASGNILAQN 223
>XP_005249886
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           A+ NILA+N
Sbjct: 215 ASGNILAQN 223
>XP_005249885
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           A+ NILA+N
Sbjct: 198 ASGNILAQN 206
>NP_115977
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 94  RNLLVEN 100
>NP_003666
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  RNILAEN 9
          RN+L EN
Sbjct: 18 RNLLVEN 24
>NP_056998
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATRNILAEN 9
           A+ N+L EN
Sbjct: 883 ASENLLTEN 891
>NP_005493
          Length = 2261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATR ++AE
Sbjct: 391 ATRQVMAE 398
>NP_001258358
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATRN+L +
Sbjct: 632 ATRNVLRQ 639
>NP_001258357
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATRN+L +
Sbjct: 653 ATRNVLRQ 660
>NP_055862
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATRN+L +
Sbjct: 654 ATRNVLRQ 661
>NP_001258356
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATRN+L +
Sbjct: 653 ATRNVLRQ 660
>NP_149047
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>NP_115935
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>NP_002636
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ATRNILAEN 9
           A RNI  EN
Sbjct: 413 AQRNICGEN 421
>NP_908975
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>NP_908974
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>NP_912730
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>NP_001026918
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           +T N+L+EN
Sbjct: 287 STPNLLSEN 295
>XP_005255403
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATRNILAEN 9
           A+ N+L EN
Sbjct: 669 ASENLLTEN 677
>XP_006719421
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           +T N+L+EN
Sbjct: 210 STPNLLSEN 218
>XP_005268863
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ATRNILAEN 9
           +T N+L+EN
Sbjct: 210 STPNLLSEN 218
>XP_005253037
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  ATRNILAEN 9
          A RNI  EN
Sbjct: 33 AQRNICGEN 41
>XP_005253036
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ATRNILAEN 9
           A RNI  EN
Sbjct: 413 AQRNICGEN 421
>XP_005253035
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ATRNILAEN 9
           A RNI  EN
Sbjct: 413 AQRNICGEN 421
>XP_005253034
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ATRNILAEN 9
           A RNI  EN
Sbjct: 413 AQRNICGEN 421
>XP_005252693
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  RNILAEN 9
          RN+L EN
Sbjct: 18 RNLLVEN 24
>XP_005252691
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  RNILAEN 9
          RN+L EN
Sbjct: 18 RNLLVEN 24
>XP_005251837
          Length = 1659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATR ++AE
Sbjct: 391 ATRQVMAE 398
>XP_005251835
          Length = 2074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATR ++AE
Sbjct: 391 ATRQVMAE 398
>XP_006717058
          Length = 2100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATR ++AE
Sbjct: 391 ATRQVMAE 398
>XP_005251833
          Length = 2203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATR ++AE
Sbjct: 331 ATRQVMAE 338
>XP_005251831
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATR ++AE
Sbjct: 391 ATRQVMAE 398
>XP_005251830
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATR ++AE
Sbjct: 391 ATRQVMAE 398
>XP_006716545
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>XP_005251373
          Length = 547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>XP_005264492
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>XP_006712116
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
>XP_005245845
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATRN+L +
Sbjct: 656 ATRNVLRQ 663
>XP_005245844
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATRNILAE 8
           ATRN+L +
Sbjct: 657 ATRNVLRQ 664
>NP_908973
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RNILAEN 9
           RN+L EN
Sbjct: 97  RNLLVEN 103
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.120    0.296 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 329,230
Number of extensions: 419
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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