Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268675                                                           18    1935
NP_001268676                                                           18    1935
XP_006715311                                                           18    1935
XP_006715310                                                           18    1935
XP_005249535                                                           18    1935
XP_006715309                                                           18    1935
XP_005249534                                                           18    1935
XP_006715308                                                           18    1935
XP_006715307                                                           18    1935
XP_005249533                                                           18    1935
NP_001017969                                                           17    3301
NP_001446                                                              17    3301
NP_963853                                                              17    3301
XP_006716793                                                           17    3301
XP_005251442                                                           17    3301
XP_005266925                                                           17    3301
XP_005266924                                                           17    3301
NP_068745                                                              17    4312
NP_741996                                                              17    4312
NP_055601                                                              17    4312
NP_061867                                                              16    5631
NP_065944                                                              16    5631
NP_113649                                                              16    5631
NP_005392                                                              16    5631
NP_065744                                                              16    5631
XP_006710761                                                           16    5631
NP_443183                                                              16    7355
NP_001265444                                                           16    7355
NP_689642                                                              16    7355
NP_056041                                                              16    7355
NP_055429                                                              16    7355
NP_597722                                                              16    7355
NP_001273967                                                           16    7355
NP_001273965                                                           16    7355
NP_001269323                                                           16    7355
NP_006639                                                              16    7355
XP_005255271                                                           16    7355
XP_005255270                                                           16    7355
XP_005255268                                                           16    7355
XP_005255267                                                           16    7355
XP_006717302                                                           16    7355
XP_005252201                                                           16    7355
XP_005252200                                                           16    7355
XP_006717301                                                           16    7355
XP_005252199                                                           16    7355
XP_005252198                                                           16    7355
XP_005252197                                                           16    7355
XP_006717300                                                           16    7355
XP_005252196                                                           16    7355
XP_005252195                                                           16    7355
XP_005252194                                                           16    7355
XP_006717041                                                           16    7355
XP_006712032                                                           16    7355
NP_001277912                                                           15    9605
NP_001191315                                                           15    9605
NP_004078                                                              15    9605
NP_001091894                                                           15    9605
XP_006713584                                                           15    9605
XP_005269356                                                           15    9605
XP_005269355                                                           15    9605
XP_005269354                                                           15    9605
XP_006713583                                                           15    9605
XP_005269349                                                           15    9605
XP_005269348                                                           15    9605
XP_005269347                                                           15    9605
XP_005269346                                                           15    9605
>NP_001268675
          Length = 915

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 581 SSLSPPINQ 589
>NP_001268676
          Length = 993

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 592 SSLSPPINQ 600
>XP_006715311
          Length = 866

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 463 SSLSPPINQ 471
>XP_006715310
          Length = 866

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 463 SSLSPPINQ 471
>XP_005249535
          Length = 932

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 529 SSLSPPINQ 537
>XP_006715309
          Length = 936

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 581 SSLSPPINQ 589
>XP_005249534
          Length = 974

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 571 SSLSPPINQ 579
>XP_006715308
          Length = 978

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 575 SSLSPPINQ 583
>XP_006715307
          Length = 982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 581 SSLSPPINQ 589
>XP_005249533
          Length = 984

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSP INQ
Sbjct: 581 SSLSPPINQ 589
>NP_001017969
          Length = 2103

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    ASLSPSINQ 9
            +SLSPS++Q
Sbjct: 2066 SSLSPSLSQ 2074
>NP_001446
          Length = 673

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ASLSPSINQ 9
           ASLSPS+++
Sbjct: 352 ASLSPSVSK 360
>NP_963853
          Length = 673

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ASLSPSINQ 9
           ASLSPS+++
Sbjct: 352 ASLSPSVSK 360
>XP_006716793
          Length = 1317

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    ASLSPSINQ 9
            +SLSPS++Q
Sbjct: 1280 SSLSPSLSQ 1288
>XP_005251442
          Length = 2073

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    ASLSPSINQ 9
            +SLSPS++Q
Sbjct: 2036 SSLSPSLSQ 2044
>XP_005266925
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ASLSPSINQ 9
           ASLSPS+++
Sbjct: 132 ASLSPSVSK 140
>XP_005266924
          Length = 484

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ASLSPSINQ 9
           ASLSPS+++
Sbjct: 163 ASLSPSVSK 171
>NP_068745
          Length = 411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLSPSIN 8
           ASLSP +N
Sbjct: 371 ASLSPGLN 378
>NP_741996
          Length = 1300

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLSPSIN 8
           ASLSP +N
Sbjct: 564 ASLSPGLN 571
>NP_055601
          Length = 2063

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SLSPSINQ 9
          SLSPS+ Q
Sbjct: 77 SLSPSVRQ 84
>NP_061867
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLSPSIN 8
           A LSPS+N
Sbjct: 362 APLSPSLN 369
>NP_065944
          Length = 1701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLSPSINQ 9
           SL+PS+N+
Sbjct: 747 SLNPSLNE 754
>NP_113649
          Length = 500

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASLSPSINQ 9
           ASL PSI Q
Sbjct: 110 ASLLPSIGQ 118
>NP_005392
          Length = 1187

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           ASL PSI++
Sbjct: 802 ASLGPSISE 810
>NP_065744
          Length = 2113

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SLSPSINQ 9
            ++SP+INQ
Sbjct: 999  NISPTINQ 1006
>XP_006710761
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLSPSIN 8
           A LSPS+N
Sbjct: 362 APLSPSLN 369
>NP_443183
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ASLSPSINQ 9
          A L PSIN+
Sbjct: 72 AVLQPSINE 80
>NP_001265444
          Length = 136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLSPSIN 8
           ASL+PSI+
Sbjct: 110 ASLAPSIS 117
>NP_689642
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ASLSPSI 7
          ASLSPS+
Sbjct: 8  ASLSPSL 14
>NP_056041
          Length = 1053

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASLSPSI 7
           ASLSPS+
Sbjct: 977 ASLSPSL 983
>NP_055429
          Length = 1843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLSPSINQ 9
            S +PSINQ
Sbjct: 1110 SKNPSINQ 1117
>NP_597722
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SLSPSIN 8
           +LSPS+N
Sbjct: 356 ALSPSVN 362
>NP_001273967
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SLSPSIN 8
           +LSPS+N
Sbjct: 356 ALSPSVN 362
>NP_001273965
          Length = 744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SLSPSIN 8
           +LSPS+N
Sbjct: 356 ALSPSVN 362
>NP_001269323
          Length = 2297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2177 AQLKPTLNQ 2185
>NP_006639
          Length = 2217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2140 AQLKPTLNQ 2148
>XP_005255271
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASLSPSI 7
           ASLSPS+
Sbjct: 922 ASLSPSL 928
>XP_005255270
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASLSPSI 7
           ASLSPS+
Sbjct: 959 ASLSPSL 965
>XP_005255268
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASLSPSI 7
           ASLSPS+
Sbjct: 961 ASLSPSL 967
>XP_005255267
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASLSPSI 7
           ASLSPS+
Sbjct: 975 ASLSPSL 981
>XP_006717302
          Length = 2148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2028 AQLKPTLNQ 2036
>XP_005252201
          Length = 2185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2140 AQLKPTLNQ 2148
>XP_005252200
          Length = 2208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2088 AQLKPTLNQ 2096
>XP_006717301
          Length = 2212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2092 AQLKPTLNQ 2100
>XP_005252199
          Length = 2215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2095 AQLKPTLNQ 2103
>XP_005252198
          Length = 2217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2140 AQLKPTLNQ 2148
>XP_005252197
          Length = 2224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2140 AQLKPTLNQ 2148
>XP_006717300
          Length = 2227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2107 AQLKPTLNQ 2115
>XP_005252196
          Length = 2242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2122 AQLKPTLNQ 2130
>XP_005252195
          Length = 2259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2139 AQLKPTLNQ 2147
>XP_005252194
          Length = 2260

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASLSPSINQ 9
            A L P++NQ
Sbjct: 2140 AQLKPTLNQ 2148
>XP_006717041
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SLSPSIN 8
           +LSPS+N
Sbjct: 356 ALSPSVN 362
>XP_006712032
          Length = 1001

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSPSINQ 9
           S +PSINQ
Sbjct: 268 SKNPSINQ 275
>NP_001277912
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>NP_001191315
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>NP_004078
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>NP_001091894
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_006713584
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_005269356
          Length = 853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_005269355
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_005269354
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_006713583
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_005269349
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_005269348
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_005269347
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
>XP_005269346
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASLSPSINQ 9
           +SLSPS+ +
Sbjct: 99  SSLSPSVEK 107
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.108    0.263 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 754,226
Number of extensions: 820
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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