Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000224                                                              18    1482
NP_852111                                                              18    1482
NP_000136                                                              18    1482
NP_000360                                                              18    1482
XP_005268094                                                           18    1482
XP_005264366                                                           18    1482
XP_006712078                                                           18    1482
NP_001264156                                                           15    9605
NP_003658                                                              15    9605
NP_001264155                                                           15    9605
NP_001230526                                                           15    9605
NP_058648                                                              15    9605
XP_005269261                                                           15    9605
XP_005247955                                                           15    9605
XP_005247954                                                           15    9605
XP_005247953                                                           15    9605
XP_005247950                                                           15    9605
XP_005247951                                                           15    9605
XP_005247949                                                           15    9605
XP_005247948                                                           15    9605
NP_150279                                                              15    9605
>NP_000224
          Length = 699

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASELSVY L
Sbjct: 449 ASELSVYTL 457
>NP_852111
          Length = 669

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASELSVY L
Sbjct: 426 ASELSVYTL 434
>NP_000136
          Length = 695

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASELSVY L
Sbjct: 452 ASELSVYTL 460
>NP_000360
          Length = 764

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASELSVY L
Sbjct: 504 ASELSVYTL 512
>XP_005268094
          Length = 764

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASELSVY L
Sbjct: 504 ASELSVYTL 512
>XP_005264366
          Length = 380

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASELSVY L
Sbjct: 130 ASELSVYTL 138
>XP_006712078
          Length = 389

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASELSVY L
Sbjct: 139 ASELSVYTL 147
>NP_001264156
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASE SV++L
Sbjct: 575 ASESSVFLL 583
>NP_003658
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASE SV++L
Sbjct: 647 ASESSVFLL 655
>NP_001264155
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASE SV++L
Sbjct: 623 ASESSVFLL 631
>NP_001230526
          Length = 1287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 732 ASETSVYV 739
>NP_058648
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 732 ASETSVYV 739
>XP_005269261
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASELSVYML 9
           ASE SV++L
Sbjct: 573 ASESSVFLL 581
>XP_005247955
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 439 ASETSVYV 446
>XP_005247954
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 527 ASETSVYV 534
>XP_005247953
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 617 ASETSVYV 624
>XP_005247950
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 618 ASETSVYV 625
>XP_005247951
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 618 ASETSVYV 625
>XP_005247949
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 618 ASETSVYV 625
>XP_005247948
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 618 ASETSVYV 625
>NP_150279
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASELSVYM 8
           ASE SVY+
Sbjct: 617 ASETSVYV 624
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.124    0.293 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 305,195
Number of extensions: 265
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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