Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_110390                                                              18    1935
XP_006724753                                                           18    1935
XP_006724752                                                           18    1935
XP_006724751                                                           18    1935
NP_001274531                                                           17    2528
NP_001020769                                                           17    2528
NP_001274529                                                           17    2528
XP_005245130                                                           17    2528
XP_005245128                                                           17    2528
XP_005245127                                                           17    2528
NP_055370                                                              17    3301
XP_005252939                                                           17    3301
NP_001243199                                                           17    4312
NP_015556                                                              17    4312
NP_001243198                                                           17    4312
NP_005202                                                              16    5631
NP_001073964                                                           16    5631
NP_001275634                                                           16    5631
NP_940880                                                              16    5631
NP_542382                                                              16    5631
NP_001012661                                                           16    5631
NP_001164102                                                           16    5631
XP_003960325                                                           16    5631
XP_006715861                                                           16    5631
XP_006715860                                                           16    5631
XP_003119208                                                           16    5631
XP_005273343                                                           16    5631
XP_003119825                                                           16    5631
NP_872577                                                              16    7355
NP_109591                                                              16    7355
NP_055855                                                              16    7355
NP_001268451                                                           16    7355
NP_001268449                                                           16    7355
NP_877954                                                              16    7355
NP_001268450                                                           16    7355
NP_001177875                                                           16    7355
NP_115874                                                              16    7355
NP_149072                                                              16    7355
NP_001275696                                                           16    7355
NP_001180298                                                           16    7355
NP_003746                                                              16    7355
XP_005260916                                                           16    7355
XP_006715071                                                           16    7355
XP_006714949                                                           16    7355
XP_006714945                                                           16    7355
XP_006714943                                                           16    7355
XP_006714942                                                           16    7355
XP_006714941                                                           16    7355
XP_006714940                                                           16    7355
XP_006714939                                                           16    7355
XP_006714938                                                           16    7355
XP_006712426                                                           16    7355
XP_006712425                                                           16    7355
XP_006712424                                                           16    7355
NP_006436                                                              15    9605
NP_001263239                                                           15    9605
NP_001138295                                                           15    9605
NP_054788                                                              15    9605
NP_056978                                                              15    9605
NP_031382                                                              15    9605
NP_001020368                                                           15    9605
NP_001012975                                                           15    9605
NP_001158012                                                           15    9605
NP_001158010                                                           15    9605
NP_061132                                                              15    9605
NP_001158009                                                           15    9605
NP_001177695                                                           15    9605
XP_006723073                                                           15    9605
XP_005254179                                                           15    9605
XP_006720435                                                           15    9605
XP_005254177                                                           15    9605
XP_006720434                                                           15    9605
XP_005254176                                                           15    9605
XP_005250289                                                           15    9605
NP_003991                                                              15    9605
>NP_110390
          Length = 282

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EDRRETG 9
           EDR+ETG
Sbjct: 200 EDRKETG 206
>XP_006724753
          Length = 272

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EDRRETG 9
           EDR+ETG
Sbjct: 190 EDRKETG 196
>XP_006724752
          Length = 273

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EDRRETG 9
           EDR+ETG
Sbjct: 191 EDRKETG 197
>XP_006724751
          Length = 283

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EDRRETG 9
           EDR+ETG
Sbjct: 201 EDRKETG 207
>NP_001274531
          Length = 924

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           ASEDR E G
Sbjct: 511 ASEDRGEAG 519
>NP_001020769
          Length = 1101

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           ASEDR E G
Sbjct: 688 ASEDRGEAG 696
>NP_001274529
          Length = 953

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           ASEDR E G
Sbjct: 540 ASEDRGEAG 548
>XP_005245130
          Length = 953

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           ASEDR E G
Sbjct: 540 ASEDRGEAG 548
>XP_005245128
          Length = 953

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           ASEDR E G
Sbjct: 540 ASEDRGEAG 548
>XP_005245127
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           ASEDR E G
Sbjct: 631 ASEDRGEAG 639
>NP_055370
          Length = 1165

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SEDRRETG 9
          +EDRRE G
Sbjct: 15 AEDRRELG 22
>XP_005252939
          Length = 1184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SEDRRETG 9
          +EDRRE G
Sbjct: 33 AEDRRELG 40
>NP_001243199
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SEDRRETG 9
           SED R TG
Sbjct: 210 SEDNRRTG 217
>NP_015556
          Length = 665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SEDRRETG 9
           SED R TG
Sbjct: 278 SEDNRRTG 285
>NP_001243198
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SEDRRETG 9
           SED R TG
Sbjct: 210 SEDNRRTG 217
>NP_005202
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ASEDRRE 7
           A EDRRE
Sbjct: 914 AQEDRRE 920
>NP_001073964
          Length = 2968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SEDRRE 7
            SEDRRE
Sbjct: 1510 SEDRRE 1515
>NP_001275634
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ASEDRRE 7
           A EDRRE
Sbjct: 914 AQEDRRE 920
>NP_940880
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EDRRETG 9
           EDR++TG
Sbjct: 675 EDRQQTG 681
>NP_542382
          Length = 178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASEDRRE 7
           ASE+RRE
Sbjct: 135 ASEERRE 141
>NP_001012661
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SEDRRE 7
           SEDRRE
Sbjct: 157 SEDRRE 162
>NP_001164102
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASEDRRE 7
           AS+DRRE
Sbjct: 340 ASKDRRE 346
>XP_003960325
          Length = 207

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EDRRETG 9
           EDR ETG
Sbjct: 107 EDRPETG 113
>XP_006715861
          Length = 2189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SEDRRE 7
            SEDRRE
Sbjct: 1510 SEDRRE 1515
>XP_006715860
          Length = 2968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SEDRRE 7
            SEDRRE
Sbjct: 1510 SEDRRE 1515
>XP_003119208
          Length = 207

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EDRRETG 9
           EDR ETG
Sbjct: 107 EDRPETG 113
>XP_005273343
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASEDRRE 7
           AS+DRRE
Sbjct: 340 ASKDRRE 346
>XP_003119825
          Length = 207

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EDRRETG 9
           EDR ETG
Sbjct: 107 EDRPETG 113
>NP_872577
          Length = 324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           + EDRR+ G
Sbjct: 312 SGEDRRKAG 320
>NP_109591
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASEDRRET 8
           ASED R+T
Sbjct: 124 ASEDARKT 131
>NP_055855
          Length = 2098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ASEDRRET 8
            +SED+R+T
Sbjct: 1033 SSEDKRKT 1040
>NP_001268451
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEDRRETG 9
           S+D+RE G
Sbjct: 298 SDDQREAG 305
>NP_001268449
          Length = 840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEDRRETG 9
           S+D+RE G
Sbjct: 298 SDDQREAG 305
>NP_877954
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEDRRETG 9
           S+D+RE G
Sbjct: 298 SDDQREAG 305
>NP_001268450
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEDRRETG 9
           S+D+RE G
Sbjct: 298 SDDQREAG 305
>NP_001177875
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EDRRETG 9
           ED R+TG
Sbjct: 139 EDERQTG 145
>NP_115874
          Length = 840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEDRRETG 9
           S+D+RE G
Sbjct: 298 SDDQREAG 305
>NP_149072
          Length = 2240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ASEDRR 6
            ASEDRR
Sbjct: 2109 ASEDRR 2114
>NP_001275696
          Length = 1030

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SEDRRETG 9
          +ED R+TG
Sbjct: 47 AEDTRDTG 54
>NP_001180298
          Length = 2240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ASEDRR 6
            ASEDRR
Sbjct: 2109 ASEDRR 2114
>NP_003746
          Length = 320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SEDRRET 8
           SED RET
Sbjct: 247 SEDTRET 253
>XP_005260916
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEDRRETG 9
           S+D+RE G
Sbjct: 298 SDDQREAG 305
>XP_006715071
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASEDRRET 8
           ASED R+T
Sbjct: 124 ASEDARKT 131
>XP_006714949
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EDRRETG 9
           ED R+TG
Sbjct: 139 EDERQTG 145
>XP_006714945
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EDRRETG 9
           ED R+TG
Sbjct: 139 EDERQTG 145
>XP_006714943
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  EDRRETG 9
          ED R+TG
Sbjct: 26 EDERQTG 32
>XP_006714942
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  EDRRETG 9
          ED R+TG
Sbjct: 26 EDERQTG 32
>XP_006714941
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  EDRRETG 9
          ED R+TG
Sbjct: 26 EDERQTG 32
>XP_006714940
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  EDRRETG 9
          ED R+TG
Sbjct: 26 EDERQTG 32
>XP_006714939
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  EDRRETG 9
          ED R+TG
Sbjct: 26 EDERQTG 32
>XP_006714938
          Length = 902

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EDRRETG 9
           ED R+TG
Sbjct: 139 EDERQTG 145
>XP_006712426
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ASEDRRET 8
           +SED+R+T
Sbjct: 339 SSEDKRKT 346
>XP_006712425
          Length = 1349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ASEDRRET 8
           +SED+R+T
Sbjct: 339 SSEDKRKT 346
>XP_006712424
          Length = 1376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ASEDRRET 8
           +SED+R+T
Sbjct: 339 SSEDKRKT 346
>NP_006436
          Length = 2335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ASEDRRETG 9
            +S+D +ETG
Sbjct: 2093 SSDDIKETG 2101
>NP_001263239
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ASEDRRET 8
          A+E+RR+T
Sbjct: 80 AAEERRKT 87
>NP_001138295
          Length = 1906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           A++DR  TG
Sbjct: 936 ATDDRSSTG 944
>NP_054788
          Length = 136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  SEDRRETG 9
          +EDR E G
Sbjct: 32 AEDREEAG 39
>NP_056978
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ASEDRRET 8
          A+E+RR+T
Sbjct: 91 AAEERRKT 98
>NP_031382
          Length = 1761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    EDRRET 8
            ED+RET
Sbjct: 1204 EDKRET 1209
>NP_001020368
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SEDRRETG 9
          S+DR+E G
Sbjct: 27 SQDRQEPG 34
>NP_001012975
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SEDRRET 8
           SED+R+T
Sbjct: 738 SEDKRKT 744
>NP_001158012
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SEDRRET 8
           SED+R+T
Sbjct: 616 SEDKRKT 622
>NP_001158010
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SEDRRET 8
           SED+R+T
Sbjct: 738 SEDKRKT 744
>NP_061132
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SEDRRET 8
           SED+R+T
Sbjct: 738 SEDKRKT 744
>NP_001158009
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SEDRRET 8
           SED+R+T
Sbjct: 770 SEDKRKT 776
>NP_001177695
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ASEDRRET 8
           A+E+RR+T
Sbjct: 175 AAEERRKT 182
>XP_006723073
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           A ED+ +TG
Sbjct: 615 AMEDKEKTG 623
>XP_005254179
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           A++DR  TG
Sbjct: 203 ATDDRSSTG 211
>XP_006720435
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           A++DR  TG
Sbjct: 937 ATDDRSSTG 945
>XP_005254177
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           A++DR  TG
Sbjct: 937 ATDDRSSTG 945
>XP_006720434
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           A++DR  TG
Sbjct: 937 ATDDRSSTG 945
>XP_005254176
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASEDRRETG 9
           A++DR  TG
Sbjct: 937 ATDDRSSTG 945
>XP_005250289
          Length = 1761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    EDRRET 8
            ED+RET
Sbjct: 1204 EDKRET 1209
>NP_003991
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SEDRRETG 9
          S+DR+E G
Sbjct: 37 SQDRQEPG 44
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.116    0.294 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 665,276
Number of extensions: 1246
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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